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US4697148A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for the excitation of a sample for NMR tomography

Assignee: Bruker Biospin MRI GmbH
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Filing: 1985-04-16
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Granted: 1987-09-29
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Expires: 2005-04-16
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Abstract

Abstract The use of longer 180° pulse sequences for the generation of spin echos is made possible according to the invention during NMR tomography using the 2d-Fourier transformation process in that the phase coding gradient between each pair of 180° pulses is switched on in such a manner that the dephasing caused between each pair of 180° pulses by the phase coding gradient is twice as great as the dephasing caused before the beginning of the first 180° pulse by the phase coding gradient. The mirror images which appear otherwise when using the known 180° pulse sequences, e.g. the Carr-Purcell-Gill-Meiboom pulse sequence, are avoided by this measure.

Inventors

  • 👤 Bernhard Strobel
  • 👤 Dieter Ratzel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 22:47
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/54; G01R33/56; G01R33/561; G01R33/5615; G01R33/5617

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 182 words
In a process for the excitation of a samples for NMR tomography, in which the sample is exposed to a homogenous magnetic field and in addition to a selection gradient and is excited by means of a 90° selection pulse, whereafter the selection gradient is replaced by a phase coding gradient of limited time duration and a read gradient, the selection gradient, the phase coding gradient and the read gradient being mutually perpendicular to each other, and wherein finally the sample, after the ending of the phase coding gradient and with prevailing read gradient, is irradiated with a sequence of 180° pulses, whereby a plurality of core induction signals is generated in the form of so-called spin echos, the improvement comprising the step of subjecting the sample to the influence of the phase coding gradient in such a manner that the dephasing caused by the influences of the phase coding gradient and of the read gradient between each pair of 180° pulses is twice as great as the dephasing effected by the influences of these two gradients before the first 180° pulse.
Claim 2
Dependent Claim 182 words
In a process for the excitation of a samples for NMR tomography, in which the sample is exposed to a homogenous magnetic field and in addition to a selection gradient and is excited by means of a 90° selection pulse, whereafter the selection gradient is replaced by a phase coding gradient of limited time duration and a read gradient, the selection gradient, the phase coding gradient and the read gradient being mutually perpendicular to each other, and wherein finally the sample, after the ending of the phase coding gradient and with prevailing read gradient, is irradiated with a sequence of 180° pulses, whereby a plurality of core induction signals is generated in the form of so-called spin echos, the improvement comprising the step of subjecting the sample to the influence of the phase coding gradient in such a manner that the dephasing caused by the influences of the phase coding gradient and of the read gradient between each pair of 180° pulses is twice as great as the dephasing effected by the influences of these two gradients before the first 180° pulse.
Claim 3
Dependent Claim 40 words
Process according to claim 1, wherein said step of subjecting includes subjecting the sample to the influence of teh phase coding gradient during the period between the end of each signal gnereation and the beginning of the subsequent 180° pulse.
Claim 4
Dependent Claim 40 words
Process according to claim 1, wherein said step of subjecting includes subjecting the sample to the influence of the phase coding gradient during the period between the end of each 180° pulse and the beginning of the subsequent signal generation.
Claim 5
Dependent Claim 45 words
Process according to claim 2 or claim 3, wherein between each pair of 180° pulses the phase coding gradient to which the sample is subjected is effective with the same strength, but for twice the duration as before the beginning of the first 180° pulse.
Claim 6
Dependent Claim 60 words
Process according to claim 2 or claim 3, wherein said step of subjecting includes subjecting the sample to the influence of the phase coding gradient in such a manner that between each pair of 180° pulses the phase coding gradient is effective for the same duration but with twice the strength as before the begininning of the first 180° pulse.
Claim 7
Dependent Claim 208 words
In a process for the excitation of a sample for NMR tomography in which the sample is exposed to a homogenous magnetic field and in addition to a selection gradient and is excited by means of a 90° selection pulse, whereafter the selection gradient is replaced by a phase coding gradient of limited time duration and a read gradient, the selection gradient, the phase coding gradient and the read gradient being mutually perpendicular to each other, and wherein finally the sample, with prevailing read gradient, is irradiated with a sequence of 180° pulses, as a result of which a plurality of core induction signals is generated in the form of so-called spin echos, the improvement comprising the steps of switching on the phase coding gradient for the first time after the first 180° pulse and thereafter periodically applying the phase coding gradient in such a manner that it is switched on once between each pair of 180° pulses for a certain period before said core induction signals are generated, and then again for another period after the end of the generation of said signals but before the beginning of the subsequent 180° pulse, so that the dephasings caused during the two switch on periods cancel out each other.
Claim 8
Dependent Claim 208 words
In a process for the excitation of a sample for NMR tomography in which the sample is exposed to a homogenous magnetic field and in addition to a selection gradient and is excited by means of a 90° selection pulse, whereafter the selection gradient is replaced by a phase coding gradient of limited time duration and a read gradient, the selection gradient, the phase coding gradient and the read gradient being mutually perpendicular to each other, and wherein finally the sample, with prevailing read gradient, is irradiated with a sequence of 180° pulses, as a result of which a plurality of core induction signals is generated in the form of so-called spin echos, the improvement comprising the steps of switching on the phase coding gradient for the first time after the first 180° pulse and thereafter periodically applying the phase coding gradient in such a manner that it is switched on once between each pair of 180° pulses for a certain period before said core induction signals are generated, and then again for another period after the end of the generation of said signals but before the beginning of the subsequent 180° pulse, so that the dephasings caused during the two switch on periods cancel out each other.
Claim 9
Dependent Claim 27 words
Process according to claim 6, wherein before and after the signal generation the phase coding gradient is effective with identical duration and strength, but with different signs.

References Cited (Backward Citations)

DE2928551A1 Cited
US4451788A Cited
DE3135335A1 Cited
EP0098426A2 Cited
EP0132975A2 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-09-28 1991-03-30 1991-09-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-09-28 1995-03-30 1995-09-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-09-28 1999-03-30 1999-09-29 $7700.00 Window Closed / Lapsed

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