US4692434A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Difluoro antivirals and intermediate therefor
Assignee: Eli Lilly and Co
•
Filing: 1984-12-04
•
Granted: 1987-09-08
•
Expires: 2004-12-04
Abstract
Abstract A 2,2-difluoro-2-desoxycarbohydrate is used to prepare antiviral nucleosides.
Inventors
- 👤 Larry W. Hertel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 01:27
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/06; C07D; C07D307/00; C07D307/02; C07D307/26; C07D307/30; C07D307/32; C07D307/33; A; A61; A61P; A61P31/00; A61P31/12; C07D317/00; C07D317/08; C07D317/10; C07D317/14; C07D317/30; C07H11/00; C07H19/16; C07H5/00; C07H5/02; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
28 words
A nucleoside of the formula ##STR11## wherein R is a base of the formula ##STR12## wherein R 2 is amino; R 3 is hydrogen, bromo, chloro or iodo.
Claim 2
Dependent Claim
28 words
A nucleoside of the formula ##STR11## wherein R is a base of the formula ##STR12## wherein R 2 is amino; R 3 is hydrogen, bromo, chloro or iodo.
Claim 3
Dependent Claim
14 words
A nucleoside of claim 1 wherein the carbohydrate moiety is in the ribose form.
Claim 4
Dependent Claim
30 words
A method of treating Herpes viral infections in mammals comprising administering to a mammal in need of such treatment an anti-Herpes viral effective amount of a compound of claim 1.
Claim 5
Dependent Claim
29 words
A pharmaceutical composition useful for treating Herpes viral infections comprising an anti-Herpes viral effective amount of a compound of claim 1 and a pharmaceutically-acceptable carrier, diluent or excipient therefor.
References Cited (Backward Citations)
US3282921A
Cited
US3870700A
Cited
US4211773A
Cited
US4352795A
Cited
GB2136425A
Cited
EP0122707A1
Cited
EP0145978A2
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-09-07 | 1991-03-09 | 1991-09-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-09-07 | 1995-03-09 | 1995-09-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-09-07 | 1999-03-09 | 1999-09-08 | $7700.00 | Window Closed / Lapsed |