US4686207A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Erythromycin A 11,12-carbonates and method of use
Assignee: Abbott Laboratories
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Filing: 1985-11-12
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Granted: 1987-08-11
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Expires: 2005-11-12
Abstract
Abstract Disclosed herein are erythromycin derivatives of the formula ##STR1## wherein R 1 is lower alkyl, aryl, alkene, aryl halide, alkylamino, hydroxyalkyl and furanyl, and pharmaceutically acceptable salts thereof. These compounds have improved oral absorption, reduced effects on gastrointestinal motility, increased acid stability and longer serum half-lives.
Inventors
- 👤 Leslie A. Freiberg
- 👤 David J. Bacino
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 13:13
CPC Classifications
C; C07; C07H; C07H17/00; C07H17/04; C07H17/08
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
23 words
A compound of the formula: ##STR4## wherein R is lower alkyl, aryl, alkene, aryl halide, alkylamino and furanyl or pharmaceutically acceptable salts thereof.
Claim 2
Dependent Claim
23 words
A compound of the formula: ##STR4## wherein R is lower alkyl, aryl, alkene, aryl halide, alkylamino and furanyl or pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim
19 words
A pharmaceutical composition comprising a therapeutically effective amount of a compound of claim 1 and a pharmaceutically acceptable carrier.
Claim 4
Dependent Claim
37 words
A method of treating and preventing bacterial infections in humans and lower animals in need of such treatment, comprising administering to the human or lower animal a therapeutically effective amount of a compound according to claim 1.
References Cited (Backward Citations)
US3842068A
Cited
US4476298A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-08-10 | 1991-02-09 | 1991-08-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-08-10 | 1995-02-09 | 1995-08-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-08-10 | 1999-02-09 | 1999-08-11 | $7700.00 | Window Closed / Lapsed |