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US4681588A Expired / Lapsed US ⏱️ 0.0 years remaining

Biomaterial

Assignee: WILKRACHT PTY Ltd
•
Filing: 1984-10-17
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Granted: 1987-07-21
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Expires: 2004-10-17
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Abstract

Abstract Material for use in a biological environment is produced by subjecting a sheet of parietal pleura to glutaraldehyde tanning. The pleura is stretched and cleansed of excessive tissue to result in a membrane of substantially uniform thickness prior to tanning. The material produced by the invention may be used as a surgical graft material, in which case the visceral surface of the pleura may provide a blood contacting surface. The material may also be used as a surgical dressing. The pleura may be obtained from various animal species but will commonly be bovine pleura.

Inventors

  • 👤 Vettivetpillai Ketharanathan

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:58
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3683; A61L27/3687; A61K; A61K35/00; A61K35/12; A61K35/42; A61L15/00; A61L15/16; A61L15/40; A61L27/3604; A61L27/50; A61L27/60; A61L2430/00; A61L2430/40

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 16 words
A biomaterial comprising a sheet of animal parietal pleura which has been subjected to glutaraldehyde tanning.
Claim 2
Dependent Claim 16 words
A biomaterial comprising a sheet of animal parietal pleura which has been subjected to glutaraldehyde tanning.
Claim 3
Dependent Claim 13 words
A material as claimed in claim 1 wherein the pleura is bovine pleura.
Claim 4
Dependent Claim 33 words
A method of producing the biomaterial of claim 1 comprising subjecting a sheet of animal parietal pleura to glutaraldehyde and tanning said sheet to provide a sheet of glutaraldehyde tanned animal parietal pleura.
Claim 5
Dependent Claim 13 words
A method as claimed in claim 3 wherein the pleura is bovine pleura.
Claim 6
Dependent Claim 29 words
A method as claimed in claim 3 wherein the pleura is stretched and cleansed of excessive tissue to result in a membrane of substantially uniform thickness prior to tanning.
Claim 7
Dependent Claim 46 words
A method as claimed in claim 3 wherein the pleura is tanned in a solution of buffered glutaraldehyde of between 2-8 pH having a concentration of 0.5%-5% by weight and is immersed in the solution for a period within the range 15 minutes to 72 hours.
Claim 8
Dependent Claim 37 words
A method of treating a living human patient comprising applying a sheet of animal parietal pleura of claim 1 which has been subjected to glutaraldehyde tanning as a surgical graft or as a dressing to the patient.
Claim 9
Dependent Claim 31 words
A method of treating a living human patient comprising applying to the patient the biomaterial produced by the method claimed in claim 3 as a surgical graft or as a dressing.
Claim 10
Dependent Claim 21 words
A method as claimed in claim 7, comprising positioning the visceral surface of the pleura to provide a blood contacting surface.
Claim 11
Dependent Claim 19 words
The biomaterial as claimed in claim 1 wherein the visceral surface of the pleura provides a blood contacting surface.
Claim 12
Dependent Claim 24 words
A shelf storable surgical graft for a living human patient adapted to support epithelial or endothelial growth composed of the biomaterial of claim 1.
Claim 13
Dependent Claim 24 words
A shelf storable surgical dressing for a living human patient adapted to support epithelial or endothelial growth composed of the biomaterial of claim 1.

References Cited (Backward Citations)

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US3988782A Cited
US4120649A Cited
GB2063675A Cited
US4275469A Cited
WO1982000091A1 Cited
US4466139A Cited
EP0052288A2 Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-07-20 1991-01-19 1991-07-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-07-20 1995-01-19 1995-07-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-07-20 1999-01-19 1999-07-21 $7700.00 Window Closed / Lapsed

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