Continuous alcohol manufacturing process using immobilized microorganism

Claim 2

A continuous alcohol manufacturing process wherein, in a fermentation system, a fermenter is packed with an alcohol-producing microorganism immobilized on a carrier; comprising the steps of continuously supplying a sugar-containing liquid to said fermenter so as to effect alcohol fermentation; continuously removing from the fermenter a portion of said fermentation liquid which has contacted said immobilized microorganism; heating said removed liquid to a temperature of from 50° to 80° C. in a heater; introducing said heated liquid into a flash tank held under reduced pressure of from 60 to 300 mm Hg absolute thereby to divide said heated liquid into an alcohol-containing vapor and a separated liquid; condensing said alcohol-containing vapor and removing it from the fermentation system; cooling said separated liquid to a temperature equal to or below the temperature within the fermenter; continuously recycling at least part of said separated liquid back to the fermenter, the flow rate at which said separated liquid is recycled into said fermenter being from 1 to 10 times the flow rate at which said sugar-containing liquid that is fed into said fermenter; and discharging a residue from the fermentation system.

Claim 3

A process according to claim 1 wherein said sugar-containing liquid has a sugar concentration of 250 to 400 g/l.

Claim 4

A process according to claim 1 wherein said immobilized microorganism is immobilized on and inside the carrier and said carrier is at least one member selected from the group consisting of agar, alginate, Kappa-carrageenan, gelatin, collagen, polyacrylamide and photocrosslinked resins.

Claim 5

A process according to claim 1 wherein said alcohol fermentation is effected under a pressure ranging from 0 to 2 Kg/cm 2 G.

Claim 6

A process according to claim 1 wherein said alcohol-containing vapor contains 20 to 60 wt.% of ethanol.

Claim 7

A process according to claim 1 wherein said separated liquid in the flash tank is cooled to a temperature of 20° to 35° C. and is recycled to the fermenter.

Claim 8

A process according to claim 1 in which said flash tank is maintained under said reduced pressure by an ejector.

Claim 9

A process according to claim 1 wherein in the fermentation system, a number n of fermenters are arranged in series, the sugar-containing liquid is continuously supplied to the first fermenter from the outside of the system, the fermentation liquid taken out of said first fermenter is then heated and introduced into a first flash tank for dividing it into a first alcohol-containing vapor and a first separated liquid; the first separated liquid is cooled and part of it is recycled to the first fermenter and the balance is introduced into the second fermenter; the fermentation liquid taken out of the second fermenter is then heated and introduced into a second flash tank for separating it into a second alcohol-containing vapor and a second separated liquid; the second separated liquid is cooled and part of it is recycled to the second fermenter; the same procedure being repeated in the same manner for each fermenter, except for the final fermenter in the series, so that a liquid separated in a given flash tank is cooled and part of it is recycled to the fermenter associated with said given flash tank and the balance is introduced into the next following fermenter to provide the fermentation liquid for the next following fermenter, and wherein in each heating step the portion of the fermentation liquid that is removed from the preceding fermenter is heated to 50° to 80° C., and each flash tank is held under a reduced pressure of 60 to 300 mg Hg absolute.

Claim 10

A process according to claim 8 wherein n is a number from 2 to 5.

Claim 11

A process according to claim 8 wherein said sugar-containing feed liquid has a sugar concentration of 250 to 400 g/l.

Claim 12

A process according to claim 8 wherein said immobilized microorganism is immobilized on and inside the carrier and said carrier is at least one member selected from the group consisting of agar, alginate, Kappa-carrageenan, gelatin, collagen, polyacrylamide and photocrosslinked resins.

Claim 13

A process according to claim 8 wherein said alcohol fermentation is effected under a pressure ranging from 0 to 2 Kg/cm 2 G.

Claim 14

A process according to claim 8 wherein said alcohol-containing vapor contains 20 to 60 wt.% of ethanol.

Claim 15

A process according to claim 8 wherein said separated liquid in the flash tank is cooled to a temperature of 20° to 35° C. and is recycled to the fermenter.

Claim 16

A process according to claim 8 in which said flash tank is maintained under said reduced pressure by an ejector.

Claim 17

A continuous alcohol manufacturing process which comprises: continuously mixing together a fermentable sugar-containing, feed liquid and a fermentable recycle liquid to form a fermentation liquid and feeding said fermentation liquid into a fermenter that is packed with an alcohol-producing microorganism which is immobilized on a solid carrier; fermenting said fermentation liquid in said fermenter at a temperature of from 25° to 35° C. and at a pressure of from 0 to 2 Kg/cm 2 G to produce alcohol; continuously removing from the fermenter a stream consisting of a portion of the fermentation liquid, heating said stream to a temperature of from 50° to 80° C. and then feeding said heated stream into a flash tank which is maintained at a reduced pressure of from 60 to 300 mm Hg absolute whereby to form in said flask tank an alcohol-containing vapor and said recycle liquid; removing said vapor from said flash tank and then condensing said vapor to obtain an alcohol-containing liquid; recovering said alcohol-containing liquid; removing said recycle liquid from said flash tank, cooling at least part of said recycle liquid to a temperature of from 20° to 35° C. and then feeding it into said fermenter as said fermentable recycle liquid, the flow rate at which said recycle liquid is recycled into said fermenter being from 1 to 10 times the flow rate at which said fermentable feed liquid is fed into said fermenter; and discharging a residue from the process.

Claim 18

A continuous alcohol manufacturing process which comprises: continuously mixing together a fermentable sugar-containing, feed liquid and a fermentable recycle liquid to form a fermentation liquid and feeding said fermentation liquid into a fermenter that is packed with an alcohol-producing microorganism which is immobilized on a solid carrier; fermenting said fermentation liquid in said fermenter at a temperature of from 25° to 35° C. and at a pressure of from 0 to 2 Kg/cm 2 G to produce alcohol; continuously removing from the fermenter a stream consisting of a portion of the fermentation liquid, heating said stream to a temperature of from 50° to 80° C. and then feeding said heated stream into a flash tank which is maintained at a reduced pressure of from 60 to 300 mm Hg absolute whereby to form in said flask tank an alcohol-containing vapor and said recycle liquid; removing said vapor from said flash tank and then condensing said vapor to obtain an alcohol-containing liquid; recovering said alcohol-containing liquid; removing said recycle liquid from said flash tank, cooling at least part of said recycle liquid to a temperature of from 20° to 35° C. and then feeding it into said fermenter as said fermentable recycle liquid, the flow rate at which said recycle liquid is recycled into said fermenter being from 1 to 10 times the flow rate at which said fermentable feed liquid is fed into said fermenter; and discharging a residue from the process.

Claim 19

A process according to claim 16 wherein said sugar-containing feed liquid has a sugar concentration of 250 to 400 g/l.

Claim 20

A process according to claim 16 wherein said immobilized microorganism is immobilized on and inside the carrier and said carrier is at least one member selected from the group consisting of agar, alginate, Kappa-carrageenan, gelatin, collagen, polyacrylamide and photocrosslinked resins.

Claim 21

A process according to claim 16 wherein said alcohol-containing vapor contains 20 to 60 wt.% of ethanol.

Claim 22

A process according to claim 16 in which said flash tank is maintained under said reduced pressure by an ejector.

Claim 23

A continuous alcohol manufacturing process, which comprises: continuously mixing together a fermentable, sugar-containing, feed liquid and a first fermentable recycle liquid to form a first fermentation liquid and feeding said first fermentation liquid into a first fermenter that is packed with an alcohol-producing microorganism which is immobilized on a solid carrier; fermenting said fermentation liquid in said first fermenter to produce alcohol; continuously removing from said first fermenter a first stream consisting of a portion of the first fermentation liquid, heating said first stream to a temperature of from 50° to 80° C. and then feeding said heated first stream into a first flash tank which is maintained at a reduced pressure of from 60 to 300 mm Hg absolute whereby to form in said first flash tank a first alcohol-containing vapor and a first separated liquid; removing said first vapor from said flash tank and then condensing said first vapor to obtain a first alcohol-containing liquid; removing said first separated liquid from said first flash tank, cooling part of said first separated liquid to a temperature of from 20° to 35° C. and then continuously feeding it into said first fermenter as said first fermentable recycle liquid, the flow rate of said first recycle liquid that is recycled into said first fermenter being from 1 to 10 times the flow rate of said fermentable feed liquid that is fed into said first fermenter; continuously mixing the balance of said first separated liquid and a second fermentable recycle liquid to form a second fermentation liquid and feeding said second fermentation liquid into a second fermenter that is packed with an alcohol-producing microorganism which is immobilized on a solid carrier; fermenting said second fermentation liquid in said second fermenter to produce alcohol; continuously removing from said second fermenter a second stream consisting of a portion of the second fermentation liquid, heating said second stream to a temperature of from 50° to 80° C. and then feeding said heated second stream into a second flash tank which is maintained at a reduced pressure of from 60 to 300 mm Hg absolute whereby to form in said second flash tank a second alcohol-containing vapor and a second separated liquid; removing said second vapor from said second flash tank and then condensing said second vapor to obtain a second alcohol-containing liquid; removing said second separated liquid from said second flash tank, cooling part of said second separated liquid to a temperature of from 20° to 35° C. and then feeding it into said second fermenter as said second fermentable recycle liquid, the flow rate of said second recycle liquid that is recycled into said second fermenter being from 1 to 10 times the flow rate of the balance of said first separated liquid that is fed into said second fermenter; and removing said first and second alcohol-containing liquids for recovery and discharging a residue of said second separated liquid.

Claim 24

A continuous alcohol manufacturing process, which comprises: continuously mixing together a fermentable, sugar-containing, feed liquid and a first fermentable recycle liquid to form a first fermentation liquid and feeding said first fermentation liquid into a first fermenter that is packed with an alcohol-producing microorganism which is immobilized on a solid carrier; fermenting said fermentation liquid in said first fermenter to produce alcohol; continuously removing from said first fermenter a first stream consisting of a portion of the first fermentation liquid, heating said first stream to a temperature of from 50° to 80° C. and then feeding said heated first stream into a first flash tank which is maintained at a reduced pressure of from 60 to 300 mm Hg absolute whereby to form in said first flash tank a first alcohol-containing vapor and a first separated liquid; removing said first vapor from said flash tank and then condensing said first vapor to obtain a first alcohol-containing liquid; removing said first separated liquid from said first flash tank, cooling part of said first separated liquid to a temperature of from 20° to 35° C. and then continuously feeding it into said first fermenter as said first fermentable recycle liquid, the flow rate of said first recycle liquid that is recycled into said first fermenter being from 1 to 10 times the flow rate of said fermentable feed liquid that is fed into said first fermenter; continuously mixing the balance of said first separated liquid and a second fermentable recycle liquid to form a second fermentation liquid and feeding said second fermentation liquid into a second fermenter that is packed with an alcohol-producing microorganism which is immobilized on a solid carrier; fermenting said second fermentation liquid in said second fermenter to produce alcohol; continuously removing from said second fermenter a second stream consisting of a portion of the second fermentation liquid, heating said second stream to a temperature of from 50° to 80° C. and then feeding said heated second stream into a second flash tank which is maintained at a reduced pressure of from 60 to 300 mm Hg absolute whereby to form in said second flash tank a second alcohol-containing vapor and a second separated liquid; removing said second vapor from said second flash tank and then condensing said second vapor to obtain a second alcohol-containing liquid; removing said second separated liquid from said second flash tank, cooling part of said second separated liquid to a temperature of from 20° to 35° C. and then feeding it into said second fermenter as said second fermentable recycle liquid, the flow rate of said second recycle liquid that is recycled into said second fermenter being from 1 to 10 times the flow rate of the balance of said first separated liquid that is fed into said second fermenter; and removing said first and second alcohol-containing liquids for recovery and discharging a residue of said second separated liquid.

Claim 25

A process according to claim 21 wherein said sugar-containing feed liquid has a sugar concentration of 250 to 400 g/l.

Claim 26

A process according to claim 21 wherein said immobilized microorganism is immobilized on and inside the carrier and said carrier is at least one member selected from the group consisting of agar, alginate, Kappa-carrageenan, gelatin, collagen, polyacrylamide and photocrosslinked resins.

Claim 27

A process according to claim 21 wherein said alcohol fermentation is effected under a pressure ranging from 0 to 2 Kg/cm 2 G.

Claim 28

A process according to claim 21 wherein said alcohol-containing vapor contains 20 to 60 wt.% of ethanol.

Claim 29

A process according to claim 21 in which first and second flash tanks are maintained under said reduced pressure by an ejector.