US4673673A
Expired / Lapsed
US
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17α-alkyl-17β-hydroxy-1α-methyl-4-androsten-3-ones, their production and use pharmaceutically
Assignee: Bayer Pharma AG
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Filing: 1985-08-06
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Granted: 1987-06-16
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Expires: 2005-08-06
Abstract
Abstract 17α-Alkyl-17β-hydroxy-1α-methyl-4-androsten-3-ones of the formula ##STR1## wherein R is a straight-chain alkyl residue of 3-8 carbon atoms, i.e., C 3-8 -n-alkyl, are pharmacologically active compounds distinguished by antiandrogenic activity, especially upon topical application.
Inventors
- 👤 Henry Laurent
- 👤 Rudolf Wiechert
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 20:33
CPC Classifications
C; C07; C07J; C07J21/00; C07J21/005; C07J21/006; A; A61; A61P; A61P3/00; A61P3/06; C07J1/00; C07J1/0003; C07J1/0033; C07J1/0037
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
16 words
A 17α-alkyl-17β-hydroxy-1α-methyl-4-androsten-3-one of the formula ##STR4## wherein R is n-alkyl of 7 or 8 carbon atoms.
Claim 2
Dependent Claim
16 words
A 17α-alkyl-17β-hydroxy-1α-methyl-4-androsten-3-one of the formula ##STR4## wherein R is n-alkyl of 7 or 8 carbon atoms.
Claim 3
Dependent Claim
19 words
A pharmaceutical composition comprising an antiandrogenically effective amount of a compound of claim 1 and a pharmaceutically acceptable carrier.
Claim 4
Dependent Claim
14 words
A pharmaceutical composition of claim 2 wherein the carrier is suitable for topical administration.
Claim 5
Dependent Claim
16 words
A pharmaceutical composition of claim 3 wherein the concentration of antiandrogenic compound is 0.5-5.0 wt. %.
Claim 6
Dependent Claim
31 words
A method of achieving an antiandrogenic effect in a patient in need of such treatment comprising topically administering to the patient an antiandrogenically effective amount of a compound of claim 1.
Claim 7
Dependent Claim
16 words
A method of claim 5 where the patient is suffering from acne, seborrhea, alopecia or hirsutism.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-06-15 | 1990-12-15 | 1991-06-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-06-15 | 1994-12-15 | 1995-06-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-06-15 | 1998-12-15 | 1999-06-16 | $7700.00 | Window Closed / Lapsed |