US4672031A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of treating the effectiveness of collagen-inhibiting compositions
Assignee: Rutgers Health
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Filing: 1986-07-23
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Granted: 1987-06-09
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Expires: 2006-07-23
Abstract
Abstract There is disclosed the use of a collagen inhibiting composition including in polymeric form select analogs of proline and processes for the manufacture and use of such a collagen-inhibiting composition to reduce scar tissue formation. There is also disclosed a method for testing the effectiveness of collagen-inhibiting compositions.
Inventors
- 👤 Darwin J. Prockop
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 22:49
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/74; A61K31/785
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
65 words
A method of testing the effectiveness of a collagen-inhibiting composition, which comprises: (a) incubating said composition for a predetermined time period in a vessel in the presence of human fibroblasts; and (b) comparing the number of cells which attach to said vessel resulting from step (a) with the number of cells produced by incubating like amounts of human fibroblasts in the absence of said composition.
Claim 2
Independent Claim
65 words
A method of testing the effectiveness of a collagen-inhibiting composition, which comprises: (a) incubating said composition for a predetermined time period in a vessel in the presence of human fibroblasts; and (b) comparing the number of cells which attach to said vessel resulting from step (a) with the number of cells produced by incubating like amounts of human fibroblasts in the absence of said composition.
Claim 3
Dependent Claim
36 words
The method as defined in claim 1 and including the steps of dissolving said composition in a suitable solvent system to form a solution of said composition and air drying said solution prior to step (a).
Claim 4
Dependent Claim
20 words
The method as defined in claim 1 wherein said solution of said composition is air dried on a cover slip.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-06-08 | 1990-12-08 | 1991-06-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-06-08 | 1994-12-08 | 1995-06-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-06-08 | 1998-12-08 | 1999-06-09 | $7700.00 | Window Closed / Lapsed |