US4668704A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for protecting and healing gastro-duodenal mucosa and the liver of mammals
Assignee: University of California, San Diego
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Filing: 1985-03-06
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Granted: 1987-05-26
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Expires: 2005-03-06
Abstract
Abstract A pharmaceutical composition comprising a fatty acid selected from the groups consisting of arachidonic and linoleic acid and a fatty acid aqueous solubilizing effective amount of a pharmaceutically acceptable water solubilizing surface active agent for said fatty acid is disclosed for protecting or healing injuries of the mammalian liver cause by heptatotoxic substances.
Inventors
- 👤 Daniel Hollander
- 👤 Andrzej S. Tarnawski
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 20:48
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/20; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K9/00; A61K9/0087; A61K9/0095
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
59 words
A method for protecting or healing injuries of the mammalian liver caused by heptatotoxic substances, which comprises: orally administrating to said mammals a liver protective effective amount of an aqueous soluble composition consisting essentially of a fatty acid selected from the group consisting of arachidonic acid and linoleic acid and a pharmaceutically acceptable water solubilizing surface active agent therefor.
Claim 2
Independent Claim
59 words
A method for protecting or healing injuries of the mammalian liver caused by heptatotoxic substances, which comprises: orally administrating to said mammals a liver protective effective amount of an aqueous soluble composition consisting essentially of a fatty acid selected from the group consisting of arachidonic acid and linoleic acid and a pharmaceutically acceptable water solubilizing surface active agent therefor.
Claim 3
Dependent Claim
13 words
A method according to claim 1 wherein the fatty acid is arachidonic acid.
Claim 4
Dependent Claim
13 words
A method according to claim 1 wherein the fatty acid is linoleic acid.
Claim 5
Dependent Claim
17 words
A method according to claim 1 wherein the surface active agent is a non-ionic surface active agent.
Claim 6
Dependent Claim
19 words
A method according to claim 4 wherein the non-ionic surface active agent is a polyethenoxy non-ionic surface active agent.
Claim 7
Dependent Claim
12 words
A method according to claim 1 wherein said heptatotoxic substance is ethanol.
Claim 8
Dependent Claim
66 words
An orally administratable pharmaceutical composition for protecting or healing the liver of a mammal or the gastro-duodenal mucosa of a mammal, said composition consisting essentially of a protective effective amount of a fatty acid selected from the group consisting of arachidonic acid and linoleic acid and a fatty acid aqueous solubilizing effective amount of a pharmaceutically acceptable water solubilizing surface active agent for said fatty acid.
Claim 9
Dependent Claim
66 words
An orally administratable pharmaceutical composition for protecting or healing the liver of a mammal or the gastro-duodenal mucosa of a mammal, said composition consisting essentially of a protective effective amount of a fatty acid selected from the group consisting of arachidonic acid and linoleic acid and a fatty acid aqueous solubilizing effective amount of a pharmaceutically acceptable water solubilizing surface active agent for said fatty acid.
Claim 10
Dependent Claim
13 words
A composition according to claim 7 wherein said fatty acid is arachidonic acid.
Claim 11
Dependent Claim
13 words
A composition according to claim 7 wherein said fatty acid is linoleic acid.
Claim 12
Dependent Claim
17 words
A composition according to claim 7 wherein the surface active agent is a non-ionic surface active agent.
Claim 13
Dependent Claim
19 words
A composition according to claim 10 wherein the non-ionic surface active agent is a polyethenoxy non-ionic surface active agent.
References Cited (Backward Citations)
US4388324A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-05-25 | 1990-11-24 | 1991-05-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-05-25 | 1994-11-24 | 1995-05-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-05-25 | 1998-11-24 | 1999-05-26 | $7700.00 | Window Closed / Lapsed |