US4666716A
Expired / Lapsed
US
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Antidiarrheal compositions and use thereof
Assignee: Richardson Vicks Inc
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Filing: 1984-09-04
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Granted: 1987-05-19
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Expires: 2004-09-04
Abstract
Abstract Antidiarrheal compositions showing enhanced antidiarrheal activity comprise a non-steroidal anti-inflammatory drug compound and a polymeric hydroabsorptive agent. A patient in need of remedial or preventive treatment of diarrhea symptoms is administered an antidiarrheally effective amount of said antidiarrheal compositions.
Inventors
- 👤 Bhogilal B. Sheth
- 👤 Sheri A. Gilbert
- 👤 Jane F. Kinsel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 15:10
CPC Classifications
A; A61; A61K; A61K45/00; A61K45/06; A61K31/00; A61K31/70; A61K31/715; A61K36/00; A61K36/18; A61K36/185; A61K36/68; A61P; A61P1/00; A61P1/12
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
68 words
An antidiarrheal composition comprising an antidiarrheal effective amount of a non-steroidal antiinflammatory propionic acid derivative selected from the group consisting of ibuprofen, naproxen, fenoprofen calcium, flurbiprofen, fenbufen and ketoprofen, and a nonionic polymeric hydroabsorptive agent selected from the group consisting of psyllium and glucomannan wherein the weight ratio of said propionic acid derivative to said hydroabsorptive agent is in the range of from about 1:30 to about 1:600.
Claim 2
Dependent Claim
68 words
An antidiarrheal composition comprising an antidiarrheal effective amount of a non-steroidal antiinflammatory propionic acid derivative selected from the group consisting of ibuprofen, naproxen, fenoprofen calcium, flurbiprofen, fenbufen and ketoprofen, and a nonionic polymeric hydroabsorptive agent selected from the group consisting of psyllium and glucomannan wherein the weight ratio of said propionic acid derivative to said hydroabsorptive agent is in the range of from about 1:30 to about 1:600.
Claim 3
Dependent Claim
47 words
An antidiarrheal composition comprising an antidiarrheal effective amount of ibuprofen and a nonionic polymeric hydroabsorptive agent selected from the group consisting of psyllium and glucomannan wherein the weight ratio of said ibuprofen to said hydroabsorptive agent is in the range of from about 1:30 to about 1:600.
Claim 4
Dependent Claim
47 words
An antidiarrheal composition comprising an antidiarrheal effective amount of ibuprofen and a nonionic polymeric hydroabsorptive agent selected from the group consisting of psyllium and glucomannan wherein the weight ratio of said ibuprofen to said hydroabsorptive agent is in the range of from about 1:30 to about 1:600.
Claim 5
Dependent Claim
11 words
A composition of claim 2 wherein the hydroabsorptive agent is psyllium.
Claim 6
Dependent Claim
19 words
A composition of claim 3 wherein the weight ratio of ibuprofen to psyllium is about 1:75 to about 1:400.
Claim 7
Dependent Claim
11 words
A composition of claim 2 wherein the hydroabsorptive agent is glucomannan.
Claim 8
Dependent Claim
19 words
A composition of claim 5 wherein the weight ratio of ibuprofen to glucomannan is about 1:75 to about 1:400.
Claim 9
Independent Claim
84 words
A method for the remedial or preventive treatment of diarrheal symptoms comprising concurrently administering to a host in need thereof an antidiarrheal effective amount of a non-steroidal antiinflammatory propionic acid derivative selected from the group consisting of ibuprofen, naproxen, fenprofen calcium, flurbiprofen, fenbufen and ketoprofen, and a nonionic polymeric hydroabsorptive agent selected from the group consisting of psyllium and glucomannan wherein the weight ratio of said propionic acid derivative to said hydroabsorptive agent is in the range of from about 1:30 to about 1:600.
Claim 10
Independent Claim
84 words
A method for the remedial or preventive treatment of diarrheal symptoms comprising concurrently administering to a host in need thereof an antidiarrheal effective amount of a non-steroidal antiinflammatory propionic acid derivative selected from the group consisting of ibuprofen, naproxen, fenprofen calcium, flurbiprofen, fenbufen and ketoprofen, and a nonionic polymeric hydroabsorptive agent selected from the group consisting of psyllium and glucomannan wherein the weight ratio of said propionic acid derivative to said hydroabsorptive agent is in the range of from about 1:30 to about 1:600.
Claim 11
Independent Claim
63 words
A method for the remedial or preventive treatment of diarrhea symptoms comprising concurrently administering to a host in need thereof an antidiarrheal effective amount of ibuprofen and a nonionic polymeric hydroabsorptive agent selected from the group consisting of psyllium and glucomannan wherein the weight ratio of said ibuprofen to said hydroabsorptive agent is in the range of from about 1:30 to about 1:600.
Claim 12
Independent Claim
63 words
A method for the remedial or preventive treatment of diarrhea symptoms comprising concurrently administering to a host in need thereof an antidiarrheal effective amount of ibuprofen and a nonionic polymeric hydroabsorptive agent selected from the group consisting of psyllium and glucomannan wherein the weight ratio of said ibuprofen to said hydroabsorptive agent is in the range of from about 1:30 to about 1:600.
Claim 13
Dependent Claim
28 words
A method for remedial or preventive treatment of diarrhea symptoms comprising administering to a host in need thereof an antidiarrheal effective amount of a composition of claim 3.
Claim 14
Dependent Claim
28 words
A method for remedial or preventive treatment of diarrhea symptoms comprising administering to a host in need thereof an antidiarrheal effective amount of a composition of claim 5.
Claim 15
Dependent Claim
28 words
A method for remedial or preventive treatment of diarrhea symptoms comprising administering to a host in need thereof an antidiarrheal effective amount of a composition of claim 4.
Claim 16
Dependent Claim
28 words
A method for remedial or preventive treatment of diarrhea symptoms comprising administering to a host in need thereof an antidiarrheal effective amount of a composition of claim 6.
References Cited (Backward Citations)
US4588589A
Cited
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1990-05-18 | 1990-11-17 | 1991-05-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-05-18 | 1994-11-17 | 1995-05-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-05-18 | 1998-11-17 | 1999-05-19 | $7700.00 | Window Closed / Lapsed |