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US4663316A Expired / Lapsed US ⏱️ 0.0 years remaining

Antibiotic clathrates and pharmaceutical compositions thereof

Assignee: Warner Lambert Co LLC
•
Filing: 1985-06-28
•
Granted: 1987-05-05
•
Expires: 2005-06-28
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Abstract

Abstract Cyclodextrin clathrates of certain unsaturated phosphorous containing antibiotics exhibit enhanced stability in pharmaceutical compositions.

Inventors

  • 👤 Fred C. Ninger
  • 👤 Weichi Liao

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 13:37
CPC Classifications
B; B82; B82Y; B82Y5/00; A; A61; A61K; A61K31/00; A61K31/66; A61K31/665; A61K47/00; A61K47/50; A61K47/69; A61K47/6949; A61K47/6951; A61P; A61P35/00; C; C07; C07F; C07F9/00; C07F9/02; C07F9/547; C07F9/655; C07F9/6552; C08; C08B; C08B37/00; C08B37/0006; C08B37/0009; C08B37/0012; C08B37/0015

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 13 words
Cyclodextrin clathrates of the antibiotic compound of phosphotrienin having the structural formula: ##STR2##
Claim 2
Dependent Claim 13 words
Cyclodextrin clathrates of the antibiotic compound of phosphotrienin having the structural formula: ##STR2##
Claim 3
Dependent Claim 9 words
The alpha-cyclodextrin clathrate of the compound of claim 1.
Claim 4
Dependent Claim 9 words
The beta-cyclodextrin clathrate of the compound of claim 1.
Claim 5
Dependent Claim 9 words
The gamma-cyclodextrin clathrate of the compound of claim 1.
Claim 6
Dependent Claim 9 words
The delta-cyclodextrin clathrate of the compound of claim 1.
Claim 7
Dependent Claim 18 words
A pharmaceutical composition containing one or more of the clathrates of claim 1 and a pharmaceutically acceptable carrier.
Claim 8
Dependent Claim 14 words
A pharmaceutical composition containing the clathrate of claim 2 and a pharmaceutically acceptable carrier.
Claim 9
Dependent Claim 14 words
A pharmaceutical composition containing the clathrate of claim 3 and a pharmaceutically acceptable carrier.
Claim 10
Dependent Claim 14 words
A pharmaceutical composition containing the clathrate of claim 4 and a pharmaceutically acceptable carrier.
Claim 11
Dependent Claim 14 words
A pharmaceutical composition containing the clathrate of claim 5 and a pharmaceutically acceptable carrier.

References Cited (Backward Citations)

US4578383A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-05-04 1990-11-03 1991-05-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-05-04 1994-11-03 1995-05-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-05-04 1998-11-03 1999-05-05 $7700.00 Window Closed / Lapsed

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