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US4659714A Expired / Lapsed US ⏱️ 0.0 years remaining

Anesthetic methods for mammals

Assignee: Dentsply Ltd
•
Filing: 1984-03-27
•
Granted: 1987-04-21
•
Expires: 2004-03-27
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Abstract

Abstract Improved methods of anesthesia for mammals, especially humans, are provided wherein the prolonging effect upon local anesthesia which is exhibited by co-administration of vasoconstrictors, especially vasoconstrictors believed to act upon alpha adrenoreceptor sites on blood vessel walls, are provided. In accordance with a preferred embodiment, alpha adrenoreceptor blocking agents are aministered subsequent to the performance of surgery or dentistry under local anesthesia accomplished through co-administration of anesthesia and vasoconstrictor to cause reduction of prolonged anesthetic effect. Seriatim procedures are facilitated under local anesthesia through employment of the present invention. Improved patient aesthetics, diminution of self-inflicted trauma, and increased sensory feedback from patients are among the benefits conferred by the present invention.

Inventors

  • 👤 Stephen R. Watt-Smith

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 10:44
CPC Classifications
A; A61; A61K; A61K45/00; A61K45/06; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/415

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 78 words
The method of anesthetizing the mouth of a mammal comprising the steps of: applying an anesthetic agent to at least a portion of the mouth of the mammal; the improvement comprising co-applying to said mouth portion an amount of a vasoconstrictor sufficient to prolong the anesthetic effect of the anesthetic agent upon the mouth portion; and subsequent to said applications administering an alpha adrenoreceptor blocking agent to said mouth portion in an amount sufficient to reduce the prolongation.
Claim 2
Independent Claim 78 words
The method of anesthetizing the mouth of a mammal comprising the steps of: applying an anesthetic agent to at least a portion of the mouth of the mammal; the improvement comprising co-applying to said mouth portion an amount of a vasoconstrictor sufficient to prolong the anesthetic effect of the anesthetic agent upon the mouth portion; and subsequent to said applications administering an alpha adrenoreceptor blocking agent to said mouth portion in an amount sufficient to reduce the prolongation.
Claim 3
Dependent Claim 13 words
The method of claim 1 wherein said co-application is simultaneous with said application.
Claim 4
Dependent Claim 18 words
The method of claim 1 wherein each of said applying, co-applying and administering steps is accomplished through injection.
Claim 5
Dependent Claim 15 words
The method of claim 3 wherein said anesthetic effect is accomplished through infiltration or blocking.
Claim 6
Dependent Claim 15 words
The method of claim 1 wherein the anesthetic agent comprises a local or topical anesthetic.
Claim 7
Dependent Claim 26 words
The method of claim 1 wherein the anesthetic agent is selected from the group consisting of lignocaine, xylocaine, novacaine, carbocaine, procaine, prilocaine, bupivacaine, cinchocaine and mepivacaine.
Claim 8
Dependent Claim 14 words
The method of claim 1 wherein the vasoconstrictor comprises a catchecolamine or catchecolamine derivative.
Claim 9
Dependent Claim 18 words
The method of claim 1 wherein the vasoconstrictor is selected from the group consisting of epinephrine and norepinephrine.
Claim 10
Dependent Claim 28 words
The method of claim 1 wherein the blocking agent is selected from the group consisting of phentolamine, phentolamine hydrochloride, phentolamine mesylate, tolazoline, yohimbine, rauwolscine, doxazosin, labetolol and prazosin.

References Cited (Backward Citations)

US3605744A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-04-20 1990-10-20 1991-04-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-04-20 1994-10-20 1995-04-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-04-20 1998-10-20 1999-04-21 $7700.00 Window Closed / Lapsed

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