US4658019A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Complement-fixing monoclonal antibody to human T cells
Assignee: Ortho Pharmaceutical Corp
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Filing: 1984-08-10
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Granted: 1987-04-14
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Expires: 2004-08-10
Abstract
Abstract Hybrid cell line for production of monoclonal antibody to an antigen found on all normal human T cells and cutaneous T lymphoma cells. The hybrid is formed by fusing splenocytes from immunized CAF1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
Inventors
- 👤 Patrick C. Kung
- 👤 Gideon Goldstein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 05:31
CPC Classifications
C; C07; C07K; C07K16/00; C07K16/18; C07K16/28; C07K16/2803; C07K16/2809; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/569; G01N33/56966; G01N33/56972; G01N33/575; G01N33/57505; A; A61; A61K; A61K38/00
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
14 words
Complement-fixing mouse monoclonal anitbody which reacts with essentially all normal human peripheral T cells.
Claim 2
Dependent Claim
14 words
Complement-fixing mouse monoclonal anitbody which reacts with essentially all normal human peripheral T cells.
Claim 3
Dependent Claim
41 words
A complement-fixing monoclonal anitbody produced by a hydridoma formed by fusion of cells from a mouse myeloma line and spleen cells from a mouse previously immunized with normal human T cells which reacts with essentially all normal human peripheral T cells.
Claim 4
Dependent Claim
41 words
A complement-fixing monoclonal anitbody produced by a hydridoma formed by fusion of cells from a mouse myeloma line and spleen cells from a mouse previously immunized with normal human T cells which reacts with essentially all normal human peripheral T cells.
Claim 5
Dependent Claim
15 words
Mouse monoclonal anitibody having the identifying characteristics of that produced by hybridoma ATCC CRL 8001.
Claim 6
Dependent Claim
15 words
Mouse monoclonal anitibody having the identifying characteristics of that produced by hybridoma ATCC CRL 8001.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-04-13 | 1990-10-13 | 1991-04-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-04-13 | 1994-10-13 | 1995-04-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-04-13 | 1998-10-13 | 1999-04-14 | $7700.00 | Window Closed / Lapsed |