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US4653010A Expired / Lapsed US ⏱️ 0.0 years remaining

Compounding system

Assignee: Baxter International Inc
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Filing: 1984-10-26
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Granted: 1987-03-24
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Expires: 2004-10-26
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Abstract

Abstract The present invention provides a fast, efficient and precise method and apparatus for compounding a large number of solutions for use in hyperalimentation therapy. The apparatus includes a host computer which maintains a data base of prescriptions to be compounded, and a high speed compounding apparatus connected to the host computer for compounding mixtures of base solutions in response to information supplied by the host computer from the prescription data base. Information can be entered concerning patients or prescriptions through a video display tube into the host computer data base. The host computer also includes provisions for a library of prestored standard prescriptions which can be recalled and associated with a given patient. A group of prescriptions to be compounded is first sorted in accordance with the types of specified base solutions and optionally sorted again based on the concentration of base solutions. The prescription information is transmitted to the compounding apparatus in sorted order thereby minimizing the required number of containers of base solution.

Inventors

  • 👤 Alan A. Figler
  • 👤 Aleandro DiGianfilippo

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 08:36
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/168; A61M5/16804; A61M5/16827; A61J; A61J3/00; A61J3/002; B; B01; B01F; B01F23/00; B01F23/40; B01F23/49; G; G05; G05D; G05D11/00; G05D11/02; G05D11/13; G05D11/131; G05D11/132

Claims Analysis

Total Claims: 105
Claim 1
Independent Claim 128 words
A method of optimizing the compounding of a plurality of mixtures to produce individual doses of mixtures, comprising the steps of: providing a plurality of sets of parameters of mixtures to be compounded from a selected group of base solutions, one set for each dose, each of said base solutions being contained in separate containers, each container having a discreet amount of a particular base solution; sorting the sets of parameters in accordance with the particular base solutions included in each set and amount of each base solution included in each set to minimize the needed quantity of containers of base solution to produce said doses; and compounding the mixtures in said sorted order thereby minimizing the needed quantity of containers of base solution to produce said doses.
Claim 2
Independent Claim 128 words
A method of optimizing the compounding of a plurality of mixtures to produce individual doses of mixtures, comprising the steps of: providing a plurality of sets of parameters of mixtures to be compounded from a selected group of base solutions, one set for each dose, each of said base solutions being contained in separate containers, each container having a discreet amount of a particular base solution; sorting the sets of parameters in accordance with the particular base solutions included in each set and amount of each base solution included in each set to minimize the needed quantity of containers of base solution to produce said doses; and compounding the mixtures in said sorted order thereby minimizing the needed quantity of containers of base solution to produce said doses.
Claim 3
Dependent Claim 23 words
A method as defined in claim 1 including: specifying parameters in a selected set as volumes to be added to the final mixture.
Claim 4
Dependent Claim 23 words
A method as defined in claim 2 including: specifying parameters in a selected set alternately as a percent of the final mixture volume.
Claim 5
Dependent Claim 23 words
A method as defined in claim 3 including: specifying parameters in a selected set alternately as a nutritional contribution to the final mixture.
Claim 6
Dependent Claim 49 words
A method as defined in claim 4 wherein: the volumes, the percentages of the mixture volume and the nutritional contributions are three forms of a set of base solution parameters for a mixture and an unspecified form of base solution parameters may be determined from a specified form thereof.
Claim 7
Dependent Claim 31 words
A method as defined in claim 4 wherein: changing one form of a set of base solution parameters produces a corresponding change in the alternate forms of said set of parameters.
Claim 8
Dependent Claim 34 words
A method as defined in claim 4 including: transmitting volume parameters of base solutions corresponding to an authorized set of parameters from a storage location to a compounding location to form the selected mixture.
Claim 9
Dependent Claim 25 words
A method as defined in claim 4 including printing an ordered sequence of labels corresponding to the sorted sequence of parameters in a selected group.
Claim 10
Dependent Claim 34 words
A method as defined in claim 8 including: forming the sorted sets of parameters into a queue having a corresponding sorted order; and forming a print queue for labels having a corresponding sorted order.
Claim 11
Dependent Claim 27 words
A method as defined in claim 4 including the steps of: forming groups of parameters; and compounding each corresponding group of mixtures in a predetermined time internal.
Claim 12
Dependent Claim 16 words
A method as defined in claim 10 including forming each group of parameters as a queue.
Claim 13
Dependent Claim 32 words
A method as defined in claim 10 including: providing an authorizing indicia for each group of parameters; and checking each indicia to determine if compounding of said corresponding mixture has been authorized.
Claim 14
Dependent Claim 16 words
A method as defined in claim 12 including: logging selected operations to form an audit trail.
Claim 15
Dependent Claim 37 words
A method as defined in claim 4 including; forming a plurality of queues wherein sets of parameters are stored as members of a selected queue; and performing said sorting step on the members of a selected queue.
Claim 16
Dependent Claim 39 words
A method as defined in claim 14 including: providing an operator settable authorization indicia for each member of a queue; and performing said sorting step on only queue members which have said authorization indicia set to a selected condition.
Claim 17
Dependent Claim 31 words
A method as defined in claim 15 including a second sorting step wherein authorized members of a queue are further sorted in accordance with the specified concentrations of corresponding base solutions.
Claim 18
Dependent Claim 56 words
A method as defined in claim 2 including: prestoring standard combinations of base solution parameters for later use; determining when at least a part of a selected mixture includes a prestored standard combination of parameters; and providing the corresponding prestored combination of parameters as said part of the set of parameters for the corresponding selected mixture.
Claim 19
Dependent Claim 36 words
A method as defined in claim 1 including: authorizing selected sets of parameters for compounding; and providing an indication for each set of authorized parameters and performing said sorting step on only authorized sets of parameters.
Claim 20
Independent Claim 112 words
A system for optimizing the compounding of a plurality of mixtures to produce individual doses of mixtures comprising: means for storing a plurality of sets of parameters of mixtures to be compounded from a selected group of base solutions, said base solutions being contained in containers, each container having a discreet amount of base solution; means for sorting said sets of parameters in accordance with the particular base solutions included in each set to minimize the required quantity of containers of base solution to produce said doses; and means for mixing the base solutions in said sorted order thereby minimizing the required quantity of containers of base solution to produce said doses.
Claim 21
Independent Claim 112 words
A system for optimizing the compounding of a plurality of mixtures to produce individual doses of mixtures comprising: means for storing a plurality of sets of parameters of mixtures to be compounded from a selected group of base solutions, said base solutions being contained in containers, each container having a discreet amount of base solution; means for sorting said sets of parameters in accordance with the particular base solutions included in each set to minimize the required quantity of containers of base solution to produce said doses; and means for mixing the base solutions in said sorted order thereby minimizing the required quantity of containers of base solution to produce said doses.
Claim 22
Dependent Claim 29 words
A system as defined in claim 19 including control means for storing parameters of a selected mixture in the form of a volume to be added to said mixture.
Claim 23
Dependent Claim 30 words
A system as defined in claim 20 wherein said control means include means for storing the parameters of a selected mixture alternately as a percent of the final mixture volume.
Claim 24
Dependent Claim 30 words
A system as defined in claim 21 wherein said control means include means for storing the parameters of a selected mixture alternately as a nutritional contribution to the final mixture.
Claim 25
Dependent Claim 31 words
A system as defined in claim 22 wherein said control means include means for determining unspecified volumes, percentages of the mixture volume or the nutritional contributions from a specified form thereof.
Claim 26
Dependent Claim 39 words
A system as defined in claim 23 wherein said control means include means for changing a selected form of a set of parameters and means for making a corresponding change in the alternate forms of said set of parameters.
Claim 27
Dependent Claim 37 words
A system as defined in claim 24 including: means for forming a plurality of queues wherein sets of parameters are stored as members of a selected queue; and means for sorting said members of said selected queue.
Claim 28
Dependent Claim 41 words
A system as defined in claim 20 including: means for prestoring standard combinations of parameters; means for identifying a said prestored standard combination to be included in a selected set; and means for including said prestored combination parameters in said set.
Claim 29
Dependent Claim 38 words
A system as defined in claim 19 including: means for authorizing selected sets of parameters for compounding; means for providing an indication for each said authorized set of parameters; and means for sorting only authorized sets of parameters.
Claim 30
Dependent Claim 35 words
A system as defined in claim 27 including: means for forming groups of sets of parameters of mixtures; and means for compounding each authorized member of a corresponding selected group in a predetermined time internal.
Claim 31
Dependent Claim 23 words
A system as defined in claim 28 wherein said means for forming groups include queuing means for forming each group as a queue.
Claim 32
Dependent Claim 14 words
A system as defined in claim 29 including means for sorting selected queue members.
Claim 33
Dependent Claim 27 words
A system as defined in claim 30 including means for printing an ordered sequence of labels corresponding to the sorted sequence of members in a selected queue.
Claim 34
Dependent Claim 14 words
A system as defined in claim 31 including: audit means for recording selected operations.
Claim 35
Dependent Claim 50 words
A system as defined in claim 30 including library means for prestoring a plurality of standard combinations of parameters, means for associating a respective name therewith, means for retrieving a named prestored, standard combination of parameters and for associating said named, prestored combination of parameters with a named queue member.
Claim 36
Dependent Claim 13 words
A system as defined in claim 33 including means for modifying queue members.
Claim 37
Dependent Claim 18 words
A system as defined in claim 29 including: means for authorizing selected members of a selected queue; and
Claim 38
Dependent Claim 7 words
means for sorting only authorized queue members.
Claim 39
Dependent Claim 7 words
means for sorting only authorized queue members.
Claim 40
Dependent Claim 22 words
A system as defined in claim 35 including further means for sorting in accordance with the specified concentrations of corresponding base solutions.
Claim 41
Dependent Claim 36 words
A system as defined in claim 27 including: means for transmitting volume parameters of base solutions corresponding to an authorized set of parameters from said storage means to said compounding means to form the selected mixture.
Claim 42
Dependent Claim 38 words
A system as defined in claim 27 including means for forming a queue of sets of authorized parameters having a corresponding sorted order; and including means for forming a print queue for labels having a corresponding sorted order.
Claim 43
Dependent Claim 44 words
A system as defined in claim 38 including: means for setting an authorizing indicia for each member in a selected queue to a predetermined state; and means for checking each said indicia to determine if said corresponding indicia has been set to said state.
Claim 44
Independent Claim 84 words
A system for compounding a plurality of selected mixtures to produce individual doses of mixture comprising: means for receiving sets of parameters for a plurality of mixtures to be compounded from a group of base solutions, one set for each dose; means for storing said sets and for selecting a set of parameters to be compounded; means for compounding a selected mixture corresponding to a selected set of parameters to produce individual doses; and means for coupling said storing means to said compounding means.
Claim 45
Independent Claim 84 words
A system for compounding a plurality of selected mixtures to produce individual doses of mixture comprising: means for receiving sets of parameters for a plurality of mixtures to be compounded from a group of base solutions, one set for each dose; means for storing said sets and for selecting a set of parameters to be compounded; means for compounding a selected mixture corresponding to a selected set of parameters to produce individual doses; and means for coupling said storing means to said compounding means.
Claim 46
Dependent Claim 23 words
A system as defined in claim 40 wherein: said means for coupling include status means for sensing the status of said compounding means.
Claim 47
Dependent Claim 20 words
A system as defined in claim 40 wherein said storing means include: means for forming said sets as a queue.
Claim 48
Dependent Claim 27 words
A system as defined in claim 42 including: means for controlling the transfer of information from selected queue members in said storage means to said compounding means.
Claim 49
Dependent Claim 29 words
A system as defined in claim 43 wherein: said receiving means includes manually operable means for entering a selected set of parameters in a first form into said queue.
Claim 50
Dependent Claim 25 words
A system as defined in claim 44 including: means for converting said set of parameters from said first form to at least a second form.
Claim 51
Dependent Claim 25 words
A system as defined in claim 45 including: means for converting said first or second forms of a set of parameters to a third form.
Claim 52
Dependent Claim 23 words
A system as defined in claim 45 including means for displaying a selected form of a set of parameters for a selected mixture.
Claim 53
Dependent Claim 19 words
A system as defined in claim 47 including: library means for storing standard combinations of parameters for standard mixtures.
Claim 54
Dependent Claim 19 words
A system as defined in claim 48 including means for naming a stored combination of parameters in said library.
Claim 55
Dependent Claim 22 words
A system as defined in claim 49 wherein: each said set of named library parameters is a member of a library queue.
Claim 56
Dependent Claim 25 words
A system as defined in claim 50 including means for manually entering a name and means for recalling a respective member of said library queue.
Claim 57
Dependent Claim 22 words
A system as defined in claim 40 wherein: said compounding means include manually operable means for entering information into said compounding means.
Claim 58
Dependent Claim 22 words
A system as defined in claim 52 wherein: said compounding means include a communications port for electrical connection to said coupling means.
Claim 59
Dependent Claim 22 words
A system as defined in claim 53 wherein said coupling means provide two-way communication between said storage means and said compounding means.
Claim 60
Dependent Claim 30 words
A system as defined in claim 54 wherein said manually operable means include means for requesting base solution information from a selected queue member for a mixture to be compounded.
Claim 61
Dependent Claim 33 words
A system as defined in claim 55 wherein: said control means include request sensing means and means for sending base solution information from a said selected queue member to said means for compounding.
Claim 62
Dependent Claim 28 words
A system as defined in claim 56 wherein: said compounding means include manually operable means for requesting base solution information from a selected queue member for immediate compounding.
Claim 63
Dependent Claim 40 words
A system as defined in claim 60 wherein: said control means include means for sending base solution information for an ordered sequence of queue members to said means for compounding in the same order as said sequence of preprinted labels.
Claim 64
Dependent Claim 35 words
A system as defined in claim 58 wherein: said control means include means for recording base solutions previously used by said compounding means, and means for transmitting a solution change command to said compounding means.
Claim 65
Dependent Claim 27 words
A system as defined in claim 59 wherein: said control means include means for detecting a change in base solution to be sent to said compounding means.
Claim 66
Dependent Claim 18 words
A system as defined in claim 45 including: means for authorizing compounding of a selected set of parameters.
Claim 67
Dependent Claim 12 words
A system in claim 61 including: means for sorting authorized parameter sets.
Claim 68
Dependent Claim 37 words
A system as defined in claim 51 wherein: said sorting means include means for sensing previously authorized parameter sets and said sorting means including means for arranging said parameter sets by base solutions used in each set.
Claim 69
Dependent Claim 21 words
A system as defined in claim 63 including concentration sensing means for arranging said parameter sets by concentration of base solution.
Claim 70
Dependent Claim 21 words
A system as defined in claim 63 including: means for printing an ordered plurality of labels corresponding to authorized parameter sets.
Claim 71
Dependent Claim 29 words
A system in claim 65 wherein: said means for coupling include means for transferring information for each said authorized parameter set from said storage means to said compounding means.
Claim 72
Independent Claim 128 words
A method for compounding a plurality of selected mixtures to produce individual doses of mixtures comprising: means for maintaining a plurality of base solutions, each base solution being contained in individual containers having a discreet amount of base solution; providing a plurality of sets of parameters of mixtures to be compounded from a selected group of base solutions, one set of parameters for each dose to be produced; storing said sets of parameters at a storing site and selecting a set to be compounded based on the particular base solution and amount required by a set to minimize the quantity of containers of base solution required; transmitting said selected set of parameters from the storing site to a compounding site; and compounding said selected mixture in response thereto.
Claim 73
Independent Claim 128 words
A method for compounding a plurality of selected mixtures to produce individual doses of mixtures comprising: means for maintaining a plurality of base solutions, each base solution being contained in individual containers having a discreet amount of base solution; providing a plurality of sets of parameters of mixtures to be compounded from a selected group of base solutions, one set of parameters for each dose to be produced; storing said sets of parameters at a storing site and selecting a set to be compounded based on the particular base solution and amount required by a set to minimize the quantity of containers of base solution required; transmitting said selected set of parameters from the storing site to a compounding site; and compounding said selected mixture in response thereto.
Claim 74
Dependent Claim 22 words
A method as defined in claim 67 wherein storing includes: forming a queue with each said parameter set being a member thereof.
Claim 75
Dependent Claim 37 words
A method as defined in claim 68 further including: sensing a selected set of parameters for a mixture entered in a first form; and inserting said entered set of parameters into said queue as a member thereof.
Claim 76
Dependent Claim 24 words
A method as defined in claim 69 including: converting said entered set of parameters from said first form to at least a second form.
Claim 77
Dependent Claim 23 words
A method as defined in claim 70 including: converting said first or second forms of a set of parameters to a third form.
Claim 78
Dependent Claim 17 words
A method as defined in claim 70 including displaying a selected form of a set of parameters.
Claim 79
Dependent Claim 17 words
A method as defined in claim 70 including: forming a library of prestored standard combinations of parameters.
Claim 80
Dependent Claim 18 words
A method as defined in claim 73 including associating a unique name with each member of said library.
Claim 81
Dependent Claim 18 words
A method as defined in claim 74 including: inserting into a selected queue member a prestored library member.
Claim 82
Dependent Claim 17 words
A method as defined in claim 75 including: modifying parameters of a selected member of said queue.
Claim 83
Dependent Claim 15 words
A method as defined in claim 76 including authorizing compounding of a selected queue member.
Claim 84
Dependent Claim 12 words
A method as defined in claim 77 including sorting authorized queue members.
Claim 85
Dependent Claim 18 words
A method as defined in claim 78 wherein: authorized queue members are sorted by type of base solution.
Claim 86
Dependent Claim 17 words
A method as defined in claim 79 including: sorting authorized queue members by concentration of base solution.
Claim 87
Dependent Claim 25 words
A method as defined in claim 80 including: transferring base solution information for an authorized queue member from a storing location to a compounding location.
Claim 88
Dependent Claim 30 words
A method as defined in claim 81 including: transferring base solution information for an ordered plurality of queue members in an order corresponding to the order of said printed labels.
Claim 89
Dependent Claim 26 words
A method as defined in claim 82 including: forming a plurality of mixtures of base solutions in the same order as said sequence of preprinted labels.
Claim 90
Dependent Claim 21 words
A method as defined in claim 79 including: printing an ordered plurality of labels corresponding to authorized and stored queue members.
Claim 91
Dependent Claim 16 words
A method as defined in claim 84 including: recording selected operations to form an audit trail.
Claim 92
Dependent Claim 13 words
A method as defined in claim 85 including: printing said recorded audit trail.
Claim 93
Independent Claim 117 words
A method of optimizing the compounding of a plurality of mixtures comprising the steps of: providing a plurality of sets of parameters of mixtures to be compounded from a group of base solutions in which each base solution is contained in a container having a discreet amount of base solution and each dose to be produced having a set of parameters associated therewith; and sorting the sets of parameters in accordance with the particular base solutions included in each of said sets; and the amount of each particular solution included in each set to minimize the quantity of containers of base solutions necessary to produce said mixtures; and printing a list of the sorted sets of parameters.
Claim 94
Independent Claim 117 words
A method of optimizing the compounding of a plurality of mixtures comprising the steps of: providing a plurality of sets of parameters of mixtures to be compounded from a group of base solutions in which each base solution is contained in a container having a discreet amount of base solution and each dose to be produced having a set of parameters associated therewith; and sorting the sets of parameters in accordance with the particular base solutions included in each of said sets; and the amount of each particular solution included in each set to minimize the quantity of containers of base solutions necessary to produce said mixtures; and printing a list of the sorted sets of parameters.
Claim 95
Dependent Claim 23 words
A method as defined in claim 87 including: specifying parameters in a selected set as volumes to be added to the final mixture.
Claim 96
Dependent Claim 23 words
A method as defined in claim 88 including: specifying parameters in a selected set alternately as a percent of the final mixture volume.
Claim 97
Dependent Claim 23 words
A method as defined in claim 89 including: specifying parameters in a selected set alternately as a nutritional contribution to the final mixture.
Claim 98
Dependent Claim 31 words
A method as defined in claim 90 wherein: changing one form of a set of base solution parameters produces a corresponding change in the alternate forms of said set of parameters.
Claim 99
Dependent Claim 27 words
A method as defined in claim 87 wherein the step of printing comprises printing an ordered list corresponding to the sorted order of the sets of parameters.
Claim 100
Independent Claim 130 words
A system for optimizing the compounding of a plurality of mixtures to produce individual doses comprising: means for receiving from a user of said system a plurality of sets of parameters for producing said doses using a plurality of base solutions, each base solution being contained in containers having discreet amounts of base solution therein; means for storing said plurality of sets of parameters of mixtures to be compounded from said group of base solutions; means for sorting said sets of parameters in accordance with the particular base solutions included in each said set and the amount of each base solution used to minimize the quantity of containers of base solutions needed to produce said doses; and means for printing an ordered list corresponding to the sorted sets of parameters.
Claim 101
Independent Claim 130 words
A system for optimizing the compounding of a plurality of mixtures to produce individual doses comprising: means for receiving from a user of said system a plurality of sets of parameters for producing said doses using a plurality of base solutions, each base solution being contained in containers having discreet amounts of base solution therein; means for storing said plurality of sets of parameters of mixtures to be compounded from said group of base solutions; means for sorting said sets of parameters in accordance with the particular base solutions included in each said set and the amount of each base solution used to minimize the quantity of containers of base solutions needed to produce said doses; and means for printing an ordered list corresponding to the sorted sets of parameters.
Claim 102
Dependent Claim 29 words
A system as defined in claim 93 including control means for storing parameters of a each mixture in the form of a volume to be added to said mixture.
Claim 103
Dependent Claim 29 words
A system as defined in claim 94 wherein said control means include means for storing the parameters of each mixture alternately as a percent of the final mixture volume.
Claim 104
Dependent Claim 29 words
A system as defined in claim 95 wherein said control means include means for storing the parameters of each mixture alternately as a nutritional contribution to the final mixture.
Claim 105
Dependent Claim 37 words
A system as defined in claim 96 wherein said control means include means for determining any unspecified volumes, percentages of the mixture volume or the nutritional contributions from a specified form of said sets of parameters thereof.

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3.5 Years (Year 4) 1990-03-23 1990-09-22 1991-03-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-03-23 1994-09-22 1995-03-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-03-23 1998-09-22 1999-03-24 $7700.00 Window Closed / Lapsed

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