US4645504A
Expired / Lapsed
US
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Implantable infection barrier seal and method
Assignee: University of California
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Filing: 1985-05-24
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Granted: 1987-02-24
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Expires: 2005-05-24
Abstract
Abstract An implantable infection barrier seal for preventing the entry of pathogens into an anatomical body, the body defining an exterior where pathogens reside and an interior where pathogens are not endemic. The body interior includes organic tissues which are not inherently exposed to the exterior. A portion of the tissue is exposed to the exterior. The seal includes an implantable infection barrier member that comprises of an inert, biologically compatible material which is bonded to the exposed tissue portion so as to shield the body interior from the pathogens residing in the exterior.
Inventors
- 👤 Charles L. Byers
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:07
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/56; A61F; A61F11/00; A61F11/04; A61F2/00; A61F2/02; A61L27/02; A61L27/12; A61F2250/00; A61F2250/0001; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293; H; H04; H04R; H04R25/00; H04R25/60; H04R25/604; H04R25/606
Claims Analysis
Total Claims: 35
Claim 1
Independent Claim
127 words
An implantable infection barrier seal for preventing the entry of pathogens into an anatomical body, said body defining an exterior where pathogens reside and an interior where pathogens are not endemic, said body interior including organic tissues, defining an opening, which are not inherently exposed to said exterior, a portion of said tissues being exposed to said exterior, comprising an implantable infection barrier member shaped to fit within said opening and comprising an inert, biologically compatible material that is capable of being bonded directly to said exposed tissue portion so as to shield said body interior from said pathogens residing in said exterior, wherein said implantable infection barrier member comprises a porous ceramic material having a pore size in the range of form 50 to 400 micrometers.
Claim 2
Dependent Claim
127 words
An implantable infection barrier seal for preventing the entry of pathogens into an anatomical body, said body defining an exterior where pathogens reside and an interior where pathogens are not endemic, said body interior including organic tissues, defining an opening, which are not inherently exposed to said exterior, a portion of said tissues being exposed to said exterior, comprising an implantable infection barrier member shaped to fit within said opening and comprising an inert, biologically compatible material that is capable of being bonded directly to said exposed tissue portion so as to shield said body interior from said pathogens residing in said exterior, wherein said implantable infection barrier member comprises a porous ceramic material having a pore size in the range of form 50 to 400 micrometers.
Claim 3
Dependent Claim
21 words
The implantable infection barrier seal as claimed in claim 1, wherein said implantable infection barrier member comprises an osteogenesis compatible material.
Claim 4
Dependent Claim
22 words
The implantable infection barrier seal as claimed in claim 1, wherein said implantable infection barrier member comprises an epithelial neogenesis compatible material.
Claim 5
Dependent Claim
19 words
The implantable infection barrier seal as claimed in claim 1, wherein said implantable infection barrier member comprises calcium hydroxy-apatite.
Claim 6
Dependent Claim
34 words
The implantable infection barrier seal as claimed in claim 1, wherein said tissues are connective tissues comprising bone, and wherein said implantable infection barrier member is bondable to said bone, thereby providing said shield.
Claim 7
Dependent Claim
37 words
The implantable infection barrier seal as claimed in claim 1, wherein said tissues are connective tissues comprise an epithelium layer, and wherein said implantable infection barrier member is bondable to said epithelium layer, thereby providing said shield.
Claim 8
Dependent Claim
23 words
The implantable infection barrier seal as claimed in claim 5 or 6, wherein said implantable infection barrier member comprises an osteogenesis compatible material.
Claim 9
Dependent Claim
19 words
The implantable infection barrier seal as claimed in claim 7, wherein said implantable infection barrier member comprises calcium hydroxy-apatite.
Claim 10
Dependent Claim
24 words
The implantable infection barrier seal as claimed in claim 5 or 6, wherein said implantable infection barrier member comprises an epithelial neogenesis compatible material.
Claim 11
Dependent Claim
20 words
The implantable infection barrier seal as claimed in claim 9, wherein said implantable infection barrier member comprises a ceramic material.
Claim 12
Dependent Claim
19 words
The implantable infection barrier seal as claimed in claim 10, wherein said implantable infection barrier member comprises calcium hydroxy-apatite.
Claim 13
Dependent Claim
128 words
An implantable infection barrier seal for preventing the entry of pathogens into an anatomical body, said body defining an exterior where pathogens reside and an interior where pathogens are not endemic, said body interior including a cochlea that has an orifice, said orifice having a bone portion, and an elongated intracochlear implant having one end adapted to be positioned inside said cochlea and another end exposed to said exterior, comprising an implantable infection barrier member shaped to fit within said orifice and comprising an inert, biologically compatible material, said barrier member being bonded to said implant and capable of being bonded to said bone portion so as to form a shield between said cochlea and said body exterior, thereby preventing the entry of said pathogens into said cochlea.
Claim 14
Dependent Claim
128 words
An implantable infection barrier seal for preventing the entry of pathogens into an anatomical body, said body defining an exterior where pathogens reside and an interior where pathogens are not endemic, said body interior including a cochlea that has an orifice, said orifice having a bone portion, and an elongated intracochlear implant having one end adapted to be positioned inside said cochlea and another end exposed to said exterior, comprising an implantable infection barrier member shaped to fit within said orifice and comprising an inert, biologically compatible material, said barrier member being bonded to said implant and capable of being bonded to said bone portion so as to form a shield between said cochlea and said body exterior, thereby preventing the entry of said pathogens into said cochlea.
Claim 15
Dependent Claim
46 words
The implantable infection barrier seal as claimed in claim 12, wherein said cochlear orifice further includes an epithelium layer that is positioned adjacent said portion, and wherein said implantable infection barrier member is bondable to said epithelium layer, thereby providing an additional barrier to said pathogens.
Claim 16
Dependent Claim
48 words
The implantable infection barrier seal as claimed in claim 12 or 13, wherein said implantable infection barrier member is generally annular and has an inner perimeter that is bonded to said implant and an outer perimeter that is bondable to both said bone portion and said epithelium layer.
Claim 17
Dependent Claim
21 words
The implantable infection barrier seal as claimed in claim 14, wherein said implantable infection barrier member comprises an osteogenesis compatible material.
Claim 18
Dependent Claim
22 words
The implantable infection barrier seal as claimed in claim 15, wherein said implantable infection barrier member comprises an epithelial neogenesis compatible material.
Claim 19
Dependent Claim
34 words
The implantable infection barrier seal as claimed in claim 16, wherein said implantable infection barrier member comprises a porous ceramic material having a pore size in the range of from 50 to 400 micrometers.
Claim 20
Dependent Claim
19 words
The implantable infection barrier seal as claimed in claim 17, wherein said implantable infection barrier member comprises calcium hydroxy-apatite.
Claim 21
Dependent Claim
37 words
The implantable infection barrier seal as claimed in claim 18, further comprising means comprising a paste-like composition of chips of said bone portion for enhancing said bonding of said implantable infection barrier member to said bone portion.
Claim 22
Independent Claim
171 words
A method of creating an implantable infection barrier seal to prevent the entry of pathogens into an anatomical body, said body defining an exterior where pathogens reside and an interior where pathogens are not endemic, said body interior including organic tissues which are not inherently exposed to said exterior, comprising exposing a portion of said tissues to said exterior, preparing said tissue portion with an opening shaped to receive said implantable infection barrier seal, forming said implantable infection barrier seal to include an implantable infection barrier member that comprises an inert, biologically compatible material which is capable of fitting within said opening and bonding to said exposed tissue portion directly, wherein said implantable infection barrier member comprises a porous ceramic material having a pore size in the range of from 50 to 400 micrometers and positioning said implantable infection barrier member adjacent to said exposed tissue portion so as to bond said member to said exposed tissue portion directly, thereby shielding said body interior from said pathogens residing in said exterior.
Claim 23
Independent Claim
171 words
A method of creating an implantable infection barrier seal to prevent the entry of pathogens into an anatomical body, said body defining an exterior where pathogens reside and an interior where pathogens are not endemic, said body interior including organic tissues which are not inherently exposed to said exterior, comprising exposing a portion of said tissues to said exterior, preparing said tissue portion with an opening shaped to receive said implantable infection barrier seal, forming said implantable infection barrier seal to include an implantable infection barrier member that comprises an inert, biologically compatible material which is capable of fitting within said opening and bonding to said exposed tissue portion directly, wherein said implantable infection barrier member comprises a porous ceramic material having a pore size in the range of from 50 to 400 micrometers and positioning said implantable infection barrier member adjacent to said exposed tissue portion so as to bond said member to said exposed tissue portion directly, thereby shielding said body interior from said pathogens residing in said exterior.
Claim 24
Dependent Claim
18 words
The method as claimed in claim 20, wherein said implantable infection barrier member comprises an osteogenesis compatible material.
Claim 25
Dependent Claim
19 words
The method as claimed in claim 20, wherein said implantable infection barrier member comprises an epithelial neogenesis compatible material.
Claim 26
Independent Claim
15 words
The method as claimed in 20, wherein said implantable infection barrier member comprises calcium hydroxy-apatite.
Claim 27
Independent Claim
182 words
A method of creating an implantable infection barrier seal to prevent the entry of pathogens into an anatomical body, said body defining an exterior where pathogens reside and an interior where pathogens are not endemic, said body interior including a cochlea that has an orifice, said orifice having a bone portion, said orifice being adapted to receive an elongated intracochlear implant one end of which is positioned inside said cochlea and another end which is exposed to said exterior, comprising exposing a portion of said orifice to said exterior, preparing said exposed orifice portion to receive said implantable infection barrier seal, providing said implantable infection barrier seal, said seal including an implantable infection barrier member that comprises of an inert, biologically compatible material which is capable of bonding to said exposed orifice portion, to provide a shield between said cochlea and said body exterior, and positioning said implantable infection barrier member adjacent to said exposed orifice portion so as to enhance said bonding of said member with said exposed orifice portion, thereby shielding said cochlea from said pathogens residing in said exterior.
Claim 28
Independent Claim
182 words
A method of creating an implantable infection barrier seal to prevent the entry of pathogens into an anatomical body, said body defining an exterior where pathogens reside and an interior where pathogens are not endemic, said body interior including a cochlea that has an orifice, said orifice having a bone portion, said orifice being adapted to receive an elongated intracochlear implant one end of which is positioned inside said cochlea and another end which is exposed to said exterior, comprising exposing a portion of said orifice to said exterior, preparing said exposed orifice portion to receive said implantable infection barrier seal, providing said implantable infection barrier seal, said seal including an implantable infection barrier member that comprises of an inert, biologically compatible material which is capable of bonding to said exposed orifice portion, to provide a shield between said cochlea and said body exterior, and positioning said implantable infection barrier member adjacent to said exposed orifice portion so as to enhance said bonding of said member with said exposed orifice portion, thereby shielding said cochlea from said pathogens residing in said exterior.
Claim 29
Dependent Claim
44 words
The method as claimed in claim 24, wherein said cochlear orifice further includes an epithelium layer that is positioned adjacent said bone portion, and wherein said implantable infection barrier member is bonded to said epithelium layer, thereby providing an additional barrier to said pathogens.
Claim 30
Dependent Claim
47 words
The method as claimed in claim 24 or 25, wherein said implantable infection barrier member is a generally annular device having an inner perimeter that is bonded to said elogated implant and an outer perimeter that is bonded to both said bone portion and said epithelium layer.
Claim 31
Dependent Claim
18 words
The method as claimed in claim 26, wherein said implantable infection barrier member comprises an osteogenesis compatible material.
Claim 32
Dependent Claim
19 words
The method as claimed in claim 27, wherein said implantable infection barrier member comprises an epithelial neogenesis compatible material.
Claim 33
Dependent Claim
17 words
The method as claimed in claim 28, wherein said implantable infection barrier member comprises a ceramic material.
Claim 34
Dependent Claim
16 words
The method as claimed in claim 29, wherein said implantable infection barrier member comprises calcium hydroxy-apatite.
Claim 35
Dependent Claim
47 words
The method as claimed in claim 30, further comprising providing a paste-like composition of chips of said bone portion to enhance said bonding of said implantable infection barrier member with said bone portion, and positioning said composition contiguous with said member to as to enhance said bonding.
References Cited (Backward Citations)
US3663965A
Cited
EP0002068A2
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-02-23 | 1990-08-25 | 1991-02-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-02-23 | 1994-08-25 | 1995-02-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-02-23 | 1998-08-25 | 1999-02-24 | $7700.00 | Window Closed / Lapsed |