Whole blood clotting timer

Claim 1

A method for determining the clotting time for a whole blood sample comprising inserting the whole blood sample into a first, radially inner compartment of a disposable cuvette in a centrifuge, inserting a blood clotting activator into a second, radially outer compartment of that cuvette which is separated from the first compartment by a ridge in the floor of the cuvette, actuating the centrifuge to cause the whole blood sample to flow radially outwardly over the ridge and to mix with the blood clotting activator in a second compartment and simultaneously starting timing means running, continuing the operation of the centrifuge to sediment the blood cells against a radially outer wall of the second compartment, periodically measuring the optical density of a part of the mixture in the second compartment radially inwardly of said wall thereof which part of the mixture is freed from blood cells, stopping the timing means when the optical density or the time rate of change of the optical density of the mixture reaches a predetermined level, thereafter stopping the centrifuge and indicating the time interval between the starting and stopping of the timing means.

Claim 2

A method for determining the clotting time for a whole blood sample comprising inserting the whole blood sample into a first, radially inner compartment of a disposable cuvette in a centrifuge, inserting a blood clotting activator into a second, radially outer compartment of that cuvette which is separated from the first compartment by a ridge in the floor of the cuvette, actuating the centrifuge to cause the whole blood sample to flow radially outwardly over the ridge and to mix with the blood clotting activator in a second compartment and simultaneously starting timing means running, continuing the operation of the centrifuge to sediment the blood cells against a radially outer wall of the second compartment, periodically measuring the optical density of a part of the mixture in the second compartment radially inwardly of said wall thereof which part of the mixture is freed from blood cells, stopping the timing means when the optical density or the time rate of change of the optical density of the mixture reaches a predetermined level, thereafter stopping the centrifuge and indicating the time interval between the starting and stopping of the timing means.