Patent US2707166A successfully refreshed from Google Patents.
US4632902A
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US
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Method for detecting biological activity in a body fluid
Assignee: Becton Dickinson and Co
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Filing: 1985-01-03
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Granted: 1986-12-30
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Expires: 2005-01-03
Abstract
Abstract A method of detections biological activity is disclosed. A nutrient growth medium which isolates antibiotics and other microbial growth inhibitors during culturing of a microorganism. The growth medium includes an aqueous dispersion of nutrient materials and an effective amount of an isolating substance or substances capable of isolating antimicrobial materials during culturing of a microorganism. The isolating substances are selected from ion exchange resins and non-functional adsorbent resins.
Inventors
- 👤 John R. Waters
- 👤 Rodney Broman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 20:50
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/02; C12Q1/04; C12Q1/16; Y; Y10; Y10S; Y10S435/00; Y10S435/803
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
102 words
A method for detecting biological activity in a body fluid sample which may contain antimicrobial material wherein: (a) a growth medium is inoculated with a body fluid sample (b) the inoculated growth is cultured under conditions conducive to the occurrence of normal metabolic processes for a period of time sufficient to cause production of metabolic byproducts, and (c) the metabolic byproducts are monitored to detect biological activity, (d) the improvement comprising incorporating into said growth medium an effective amount of a resin capable of isolating any antimicrobial material present in said body fluid sample without hindering biological activity during said culturing period.
Claim 2
Independent Claim
102 words
A method for detecting biological activity in a body fluid sample which may contain antimicrobial material wherein: (a) a growth medium is inoculated with a body fluid sample (b) the inoculated growth is cultured under conditions conducive to the occurrence of normal metabolic processes for a period of time sufficient to cause production of metabolic byproducts, and (c) the metabolic byproducts are monitored to detect biological activity, (d) the improvement comprising incorporating into said growth medium an effective amount of a resin capable of isolating any antimicrobial material present in said body fluid sample without hindering biological activity during said culturing period.
Claim 3
Dependent Claim
13 words
The method of claim 1 wherein said resin is an ion exchange resin.
Claim 4
Dependent Claim
13 words
The method of claim 1 wherein said resin is a non-functional resin adsorbent.
Claim 5
Dependent Claim
20 words
The method of claim 1 wherein said resin is a non-functional resin adsorbent in combination with an ion exchange resin.
Claim 6
Dependent Claim
17 words
The method of claim 2 or 4 wherein said ion exchange resin is a cationic exchange resin.
Claim 7
Dependent Claim
15 words
The method of claim 5 wherein the cationic exchange resin is in the sodium form.
Claim 8
Dependent Claim
39 words
The method of claim 1 wherein the resin is selected from the group consisting of a non-functional copolymer of divinyl benzene and styrene, an ion exchange resin which is a copolymer of divinyl benzene and styrene and combinations thereof.
Claim 9
Dependent Claim
12 words
The method of claim 1 wherein the body fluid sample is blood.
Claim 10
Dependent Claim
12 words
The method of claim 1 wherein the body fluid sample is urine.
Claim 11
Dependent Claim
13 words
The method of claim 1 wherein the body fluid sample is spinal fluid.
Claim 12
Dependent Claim
13 words
The method of claim 1 wherein the body fluid sample is peritoneal fluid.
Claim 13
Dependent Claim
11 words
The method of claim 1 wherein said resin is detergent coated.
References Cited (Backward Citations)
US4174277A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-12-29 | 1990-06-30 | 1990-12-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-12-29 | 1994-06-30 | 1994-12-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-12-29 | 1998-06-30 | 1998-12-30 | $7700.00 | Window Closed / Lapsed |