← Back to Patent Explorer
US4629703A Expired / Lapsed US ⏱️ 0.0 years remaining

Automated analytical system

Assignee: Bayer Corp
•
Filing: 1983-01-14
•
Granted: 1986-12-16
•
Expires: 2003-01-14
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract A discrete-type analytical system comprising a cuvette tray which is adapted for bidirectional rotation, so as to ensure accurate repositioning of individual reaction cuvettes at one or more treatment stations.

Inventors

  • 👤 Kenneth F. Uffenheimer

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 14:00
CPC Classifications
G; G01; G01N; G01N35/00; G01N35/02; G01N35/025; Y; Y10; Y10T; Y10T436/00; Y10T436/11; Y10T436/111666; Y10T436/113332

Claims Analysis

Total Claims: 20
Claim 1
Independent Claim 222 words
A method for effecting multiple colorimetric measurements of a liquid sample contained in a selected cuvette carried on a bidirectionally rotatable cuvette tray supporting a plurality of cuvettes, each cuvette being provided with opposing transparent walls to define a sight passageway for the reading of liquid sample contained therein at a read-out station, which method comprises: (1) locating a selected cuvette in a liquid dispensing station and dispensing liquid therein; (2) rotating said cuvette tray in a first direction and stopping the rotation of the tray to locate said selected cuvette at a read-out station; (3) colorimetrically measuring said liquid in said selected cuvette at said read-out station to generate a first signal; (4) rotating said cuvette tray in a second and opposite direction; (5) repositioning said selected cuvette at said read-out station by rotating said cuvette tray in said first direction and stopping the rotation to locate said cuvette at said read-out station, wherein by using the same section of the drive system said cuvette is thereby accurately repositioned at said read-out station in order that the same portion of said opposing transparent walls define said sight passageway; (6) colorimetrically measuring the liquid in said selected cuvette following the repositioning of said selected cuvette at said read-out station to generate a second signal; and (7) storing said first and second signals.
Claim 2
Independent Claim 222 words
A method for effecting multiple colorimetric measurements of a liquid sample contained in a selected cuvette carried on a bidirectionally rotatable cuvette tray supporting a plurality of cuvettes, each cuvette being provided with opposing transparent walls to define a sight passageway for the reading of liquid sample contained therein at a read-out station, which method comprises: (1) locating a selected cuvette in a liquid dispensing station and dispensing liquid therein; (2) rotating said cuvette tray in a first direction and stopping the rotation of the tray to locate said selected cuvette at a read-out station; (3) colorimetrically measuring said liquid in said selected cuvette at said read-out station to generate a first signal; (4) rotating said cuvette tray in a second and opposite direction; (5) repositioning said selected cuvette at said read-out station by rotating said cuvette tray in said first direction and stopping the rotation to locate said cuvette at said read-out station, wherein by using the same section of the drive system said cuvette is thereby accurately repositioned at said read-out station in order that the same portion of said opposing transparent walls define said sight passageway; (6) colorimetrically measuring the liquid in said selected cuvette following the repositioning of said selected cuvette at said read-out station to generate a second signal; and (7) storing said first and second signals.
Claim 3
Dependent Claim 29 words
The method of claim 1 wherein rotating said cuvette tray in said second and opposite direction comprises positioning one of said plurality of cuvettes at a liquid dispensing station.
Claim 4
Dependent Claim 51 words
The method of claim 2 wherein rotating said cuvette tray in said first direction of step 2 comprises rotating said cuvette tray through N angular positions in said first direction and rotating said cuvette tray in said second and opposite direction comprises rotating said cuvette tray less than N angular positions.
Claim 5
Dependent Claim 21 words
The method of claim 1 which further comprises mixing the contents of said selected cuvette prior to colorimetrically measuring said liquid.
Claim 6
Dependent Claim 28 words
The method of claim 4 wherein said mixing comprises advancing said cuvette tray in said first direction in incremental steps with a momentary abrupt stop after each step.
Claim 7
Independent Claim 244 words
A method for effecting multiple colorimetric measurements of liquid samples contained in a plurality of cuvettes supported on a bidirectionally rotatable cuvette tray, each cuvette being provided with opposing transparent walls to define a sight passageway for measuring the liquid sample contained therein, wherein at least one treatment station and at least one read-out station are positioned with respect to said cuvette tray, which method comprises: (1) introducing reagent into successive cuvettes positioned, in turn, at a first treatment station; (2) introducing sample to be reacted into said reagent-containing successive cuvettes positioned, in turn, at a second treatment station and reacting said sample; (3) rotating said cuvette tray subsequent to the positioning of selected cuvettes at said treatment stations to mix the contents thereof by advancing said cuvette tray in incremental steps with a momentary abrupt stop after each step; (4) rotating said cuvette tray in a first direction subsequent to the mixing of the contents of said selected cuvettes to pass a number of said mixed cuvettes through a read-out station; and (5) subsequently rotating said cuvette tray in a second and opposite direction and stopping the rotation of said tray to position each of said mixed cuvettes which has been passed through said read-out station, in turn, at said read-out station by using the same section of the drive system such that the same portions of said opposing transparent walls define said sight passageway, in order to colorimetrically measure the contents thereof.
Claim 8
Independent Claim 244 words
A method for effecting multiple colorimetric measurements of liquid samples contained in a plurality of cuvettes supported on a bidirectionally rotatable cuvette tray, each cuvette being provided with opposing transparent walls to define a sight passageway for measuring the liquid sample contained therein, wherein at least one treatment station and at least one read-out station are positioned with respect to said cuvette tray, which method comprises: (1) introducing reagent into successive cuvettes positioned, in turn, at a first treatment station; (2) introducing sample to be reacted into said reagent-containing successive cuvettes positioned, in turn, at a second treatment station and reacting said sample; (3) rotating said cuvette tray subsequent to the positioning of selected cuvettes at said treatment stations to mix the contents thereof by advancing said cuvette tray in incremental steps with a momentary abrupt stop after each step; (4) rotating said cuvette tray in a first direction subsequent to the mixing of the contents of said selected cuvettes to pass a number of said mixed cuvettes through a read-out station; and (5) subsequently rotating said cuvette tray in a second and opposite direction and stopping the rotation of said tray to position each of said mixed cuvettes which has been passed through said read-out station, in turn, at said read-out station by using the same section of the drive system such that the same portions of said opposing transparent walls define said sight passageway, in order to colorimetrically measure the contents thereof.
Claim 9
Dependent Claim 33 words
The method of claim 6 comprising the further step of positioning a next successive cuvette at said treatment station during rotation of said cuvette tray in said second direction, as in step (5).
Claim 10
Dependent Claim 43 words
The method of claim 6 wherein step (4) comprises rotating said cuvette tray a number N of angular positions in said first direction and step (5) comprises rotating said cuvette tray a number of angular positions less than N in said second direction.
Claim 11
Dependent Claim 24 words
The method of claim 8 wherein at least a portion of step (5) is effected at a same or faster rate than step (4).
Claim 12
Dependent Claim 34 words
The method of claim 9 comprising the further step of normalizing said cuvette tray by rotating in said second direction, as in step (5), to position a next successive cuvette at said treatment station.
Claim 13
Dependent Claim 25 words
The method of claim 8 wherein step (5) comprises rotating said cuvette tray a number of angular positions equal to N-1 in said second direction.
Claim 14
Independent Claim 240 words
A method for effecting multiple colorimetric measurements of liquid samples contained in a plurality of cuvettes supported on a bidirectionally rotatable cuvette tray, each cuvette being provided with opposing transparent walls to define a sight passageway for measuring the liquid sample contained therein, wherein at least one treatment station and at least one read-out station are positioned with respect to said cuvette tray, which method comprises: (1) introducing sample to be reacted into successive cuvettes positioned, in turn, at a first treatment station. (2) introducing reagent into said sample-containing successive cuvettes positioned, in turn, at a second treatment station, and reacting said sample; (3) rotating said cuvette tray subsequent to the positioning of selected cuvettes at said treatment stations to mix the contents thereof by advancing said cuvette tray in incremental step with a momentary abrupt stop after each step; (4) rotating said cuvette tray subsequent to the mixing of the contents of said selected cuvettes to pass a number of said mixed cuvettes through a read-out station; and (5) subsequently rotating said cuvette tray in a second and opposite direction and stopping the rotation of said tray to position each of said mixed cuvettes which has been passed through said read-out station, in turn, at said read-out station by using the same section of the drive system such that the same portions of said opposing transparent walls define said sight passageway, in order to colorimetrically measure the contents thereof.
Claim 15
Independent Claim 240 words
A method for effecting multiple colorimetric measurements of liquid samples contained in a plurality of cuvettes supported on a bidirectionally rotatable cuvette tray, each cuvette being provided with opposing transparent walls to define a sight passageway for measuring the liquid sample contained therein, wherein at least one treatment station and at least one read-out station are positioned with respect to said cuvette tray, which method comprises: (1) introducing sample to be reacted into successive cuvettes positioned, in turn, at a first treatment station. (2) introducing reagent into said sample-containing successive cuvettes positioned, in turn, at a second treatment station, and reacting said sample; (3) rotating said cuvette tray subsequent to the positioning of selected cuvettes at said treatment stations to mix the contents thereof by advancing said cuvette tray in incremental step with a momentary abrupt stop after each step; (4) rotating said cuvette tray subsequent to the mixing of the contents of said selected cuvettes to pass a number of said mixed cuvettes through a read-out station; and (5) subsequently rotating said cuvette tray in a second and opposite direction and stopping the rotation of said tray to position each of said mixed cuvettes which has been passed through said read-out station, in turn, at said read-out station by using the same section of the drive system such that the same portions of said opposing transparent walls define said sight passageway, in order to colorimetrically measure the contents thereof.
Claim 16
Dependent Claim 33 words
The method of claim 12 comprising the further step of positioning a next successive cuvette at said treatment station during rotation of said cuvette tray in said second direction, as in step (5).
Claim 17
Dependent Claim 43 words
The method of claim 12 wherein step (4) comprises rotating said cuvette tray a number N of angular positions in said first direction and step (5) comprises rotating said cuvette tray a number of angular positions less than N in said second direction.
Claim 18
Dependent Claim 24 words
The method of claim 14 wherein at least a portion of step (5) is effected at a same or faster rate than step (4).
Claim 19
Dependent Claim 34 words
The method of claim 15 comprising the further step of normalizing said cuvette tray by rotating in said second direction, as in step (5), to position a next successive cuvette at said treatment station.
Claim 20
Dependent Claim 25 words
The method of claim 14 wherein step (5) comprises rotating said cuvette tray a number of angular positions equal to N-1 in said second direction.

References Cited (Backward Citations)

US3615222A Cited
US3718439A Cited
US3829223A Cited
JPS5240189A Cited
US4058367A Cited
US4135883A Cited
US4225558A Cited
US4325910A Cited
US4313735A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-12-15 1990-06-16 1990-12-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-12-15 1994-06-16 1994-12-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-12-15 1998-06-16 1998-12-16 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag