US4621085A
Expired / Lapsed
US
⏱️ 0.0 years remaining
2,4,7-triamino-6-phenylpteridine
Assignee: Roehm GmbH Darmstadt
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Filing: 1985-04-03
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Granted: 1986-11-04
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Expires: 2005-04-03
Abstract
Abstract The present invention relates to pharmaceutical preparations with cardiac, particularly anti-arrhythmic activity. These preparations comprise, as an active principle, at least one compound of formula I: ##STR1## where R represents a lipophilic radical. The pharmaceutical compositions may comprise this compound in the presence of other pharmaceutical excipients and adjuvants.
Inventors
- 👤 Ulrich Borchard
- 👤 Ernst Mutschler
- 👤 Werner Moehrke
- 👤 Karl-Dieter Voelger
- 👤 Erwin Wolf
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 16:38
CPC Classifications
C; C07; C07D; C07D475/00; C07D475/06; C07D475/08; A; A61; A61P; A61P9/00; A61P9/06
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
38 words
A pharmaceutical composition comprising an anti-arryhythmic effective amount of a compound of the formula: ##STR6## wherein R is a radical selected from the group consisting of, sec-butyl, tert-butyl, neopentyl, cyclohexyl, and benzyl, said composition having anti-arrhythmic cardiac activity.
Claim 2
Dependent Claim
38 words
A pharmaceutical composition comprising an anti-arryhythmic effective amount of a compound of the formula: ##STR6## wherein R is a radical selected from the group consisting of, sec-butyl, tert-butyl, neopentyl, cyclohexyl, and benzyl, said composition having anti-arrhythmic cardiac activity.
Claim 3
Dependent Claim
24 words
The pharmaceutical composition of claim 1, wherein the active ingredient is present in an amount of from 1 to 100 mg per dose unit.
Claim 4
Dependent Claim
21 words
The pharmaceutical composition of claim 1, said composition further comprising mannitol, lactrose, an organic calcium salt or an inorganic calcium salt.
Claim 5
Dependent Claim
18 words
The pharmaceutical composition of claim 1, said composition further comprising polyvinyl pyrrolidone, a gelatin or a cellulose derivative.
Claim 6
Independent Claim
48 words
A method for the treatment of cardiac arrhythmias, which comprises administering an anti-arrhythmic effective amount of a compound of the formula: ##STR7## wherein R is a C 3 to C 6 alkyl group which is saturated or unsaturated, a benzyl group, a trifluoromethyl group, or a nitro group.
Claim 7
Independent Claim
48 words
A method for the treatment of cardiac arrhythmias, which comprises administering an anti-arrhythmic effective amount of a compound of the formula: ##STR7## wherein R is a C 3 to C 6 alkyl group which is saturated or unsaturated, a benzyl group, a trifluoromethyl group, or a nitro group.
Claim 8
Independent Claim
53 words
A method for the treatment of cardiac arrhythmias, which comprises administering an anti-arrhythmic effective amount of compound of the formula: ##STR8## wherein R is a fluorine atom, a chlorine atom, a C 3 to C 6 alkyl group which is branched or cyclic, a benzyl group, a trifluoromethyl group, or a nitro group.
Claim 9
Independent Claim
53 words
A method for the treatment of cardiac arrhythmias, which comprises administering an anti-arrhythmic effective amount of compound of the formula: ##STR8## wherein R is a fluorine atom, a chlorine atom, a C 3 to C 6 alkyl group which is branched or cyclic, a benzyl group, a trifluoromethyl group, or a nitro group.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-11-03 | 1990-05-05 | 1990-11-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-11-03 | 1994-05-05 | 1994-11-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-11-03 | 1998-05-05 | 1998-11-04 | $7700.00 | Window Closed / Lapsed |