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US4621029A Expired / Lapsed US ⏱️ 0.0 years remaining

Medical sealant for skin

Assignee: Fuji Systems Corp
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Filing: 1985-01-11
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Granted: 1986-11-04
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Expires: 2005-01-11
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Abstract

Abstract This invention relates to a medical sealant comprising polyorganosiloxane gel for sealing a junction part between living skin and a medical instrument penetrating through the skin, said polyorganosiloxane gel having a partially cross-linked three dimentional structure expressed by the basis general formula of R.sub.n SiO.sub.(4-n)/2 (wherein R represents hydrogen or monovalent hydrocarbonyl group and n represents an integer of 1 to 3), characterized in that said gel self-supports its figure at room temperature and has a hardness expressed by a loading weight of 1 g to 250 g by which a disc of a diameter of 10 mm sinks to 1.0 mm on the gel.

Inventors

  • 👤 Nobuhisa Kawaguchi

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 17:26
CPC Classifications
A; A61; A61L; A61L24/00; A61L24/04; A61L24/046; Y; Y10; Y10S; Y10S528/00; Y10S528/901; Y10T; Y10T428/00; Y10T428/14; Y10T428/1438; Y10T428/19; Y10T428/192; Y10T428/195; Y10T428/31504; Y10T428/31652; Y10T428/31663

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 133 words
A medical sealant having a thickness of at least 2 mm comprising polyorganosiloxane gel for sealing a junction part between living skin and a medical instrument penetrating through the skin, said polyorganosiloxane having a three dimensional structure expressed by the general formula R.sub.n SiO.sub.(4-n/2) wherein R represents hydrogen or monovalent hydrocarbon group having not more than 6 carbon atoms and n represents an integer of 1 to 3, characterized in that said gel contains an effective amount of a silicone oil, not exceeding 500 parts by weight of silicone oil per 100 parts by weight of said polyorganosiloxane gel so that the sealant has a hardness expressed by a loading weight of 1 g to 250 g by which a disc of a diameter of 10 mm sinks to 1.0 on the gel.
Claim 2
Dependent Claim 133 words
A medical sealant having a thickness of at least 2 mm comprising polyorganosiloxane gel for sealing a junction part between living skin and a medical instrument penetrating through the skin, said polyorganosiloxane having a three dimensional structure expressed by the general formula R.sub.n SiO.sub.(4-n/2) wherein R represents hydrogen or monovalent hydrocarbon group having not more than 6 carbon atoms and n represents an integer of 1 to 3, characterized in that said gel contains an effective amount of a silicone oil, not exceeding 500 parts by weight of silicone oil per 100 parts by weight of said polyorganosiloxane gel so that the sealant has a hardness expressed by a loading weight of 1 g to 250 g by which a disc of a diameter of 10 mm sinks to 1.0 on the gel.
Claim 3
Dependent Claim 15 words
The sealant according to claim 1 further comprising a backing sheet supporting said polyorganosiloxane gel.
Claim 4
Dependent Claim 13 words
The sealant according to claim 1 further comprising a medicine for external application.
Claim 5
Dependent Claim 10 words
The sealant according to claim 1 further comprising a sterilant.
Claim 6
Dependent Claim 10 words
The sealant according to claim 1 further comprising zinc oxide.
Claim 7
Dependent Claim 31 words
The medical sealant according to claim 1, wherein an amount of said silicone oil added is 100 to 300 parts by weight per 100 parts by weight of said polyorganosiloxane gel.
Claim 8
Dependent Claim 21 words
The medical sealant according to claim 1, wherein said silicone oil is polydimethylsiloxane having a viscosity of 20 to 50,000 cs.
Claim 9
Dependent Claim 18 words
The medical sealant according to claim 7, where said polydimethylsiloxane has a viscosity of 20 to 1,000 cs.
Claim 10
Dependent Claim 222 words
A self-supporting, human skin adherable, medical sealant member having a thickness of at least 2 mm for interposition between living skin and a medical instrument penetrating through said skin to seal a juncture between said skin and said medical instrument penetrating through said skin, said medical sealant member comprising a polyorganosiloxane gel having a three dimensional structure expressed by the formula R.sub.n SiO.sub.(4-n/2) wherein R represents hydrogen or monovalent hydrocarbon group and n represents an integer of 1 to 3 consisting essentially of a linear polyorganosiloxane having the formula ##STR6## wherein R 1 , R 2 , R 3 and R 4 , which may be the same or different, represent hydrogen, monovalent hydrocarbon, alkoxy, acyl or hydroxyl, and m and o are numbers chosen so that the viscosity of the linear polyorganosiloxane is in the range of from 1,000 cs to 1,000,000 cs at 25° C., cross-linked in the presence of a polydimethylsiloxane having a viscosity in the range of 20 cs to 50,000 cs, said polydimethylsiloxane being present in an amount, not exceeding 500 parts by weight per 100 parts by weight of linear polyorganosiloxane, effective to produce a gel having a hardness such that the weight necessary to sink a disc of 10 mm diameter 1 mm into the gel lies within the range 1 g to 250 g.
Claim 11
Dependent Claim 222 words
A self-supporting, human skin adherable, medical sealant member having a thickness of at least 2 mm for interposition between living skin and a medical instrument penetrating through said skin to seal a juncture between said skin and said medical instrument penetrating through said skin, said medical sealant member comprising a polyorganosiloxane gel having a three dimensional structure expressed by the formula R.sub.n SiO.sub.(4-n/2) wherein R represents hydrogen or monovalent hydrocarbon group and n represents an integer of 1 to 3 consisting essentially of a linear polyorganosiloxane having the formula ##STR6## wherein R 1 , R 2 , R 3 and R 4 , which may be the same or different, represent hydrogen, monovalent hydrocarbon, alkoxy, acyl or hydroxyl, and m and o are numbers chosen so that the viscosity of the linear polyorganosiloxane is in the range of from 1,000 cs to 1,000,000 cs at 25° C., cross-linked in the presence of a polydimethylsiloxane having a viscosity in the range of 20 cs to 50,000 cs, said polydimethylsiloxane being present in an amount, not exceeding 500 parts by weight per 100 parts by weight of linear polyorganosiloxane, effective to produce a gel having a hardness such that the weight necessary to sink a disc of 10 mm diameter 1 mm into the gel lies within the range 1 g to 250 g.
Claim 12
Dependent Claim 31 words
The medical sealant member according to claim 9, wherein said polydimethylsiloxane is present in an amount of 100 to 300 parts by weight per 100 parts by weight of linear polyorganosiloxane.
Claim 13
Dependent Claim 23 words
The medical sealant member according to claim 9, wherein said polydimethylsiloxane has a viscosity in the range of 20 cs to 1,000 cs.

References Cited (Backward Citations)

US4316941A Cited
US4322320A Cited
US4460371A Cited
US4526922A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-11-03 1990-05-05 1990-11-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-11-03 1994-05-05 1994-11-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-11-03 1998-05-05 1998-11-04 $7700.00 Window Closed / Lapsed

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