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US4608252A Expired / Lapsed US ⏱️ 0.0 years remaining

Chloramphenicol derivatives antigens and antibodies

Assignee: Siemens Healthcare Diagnostics GmbH Germany
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Filing: 1985-09-27
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Granted: 1986-08-26
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Expires: 2005-09-27
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Abstract

Abstract Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxo-carbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and find particular use in competitive protein binding assays.

Inventors

  • 👤 Pyare Khanna
  • 👤 Evan S. Snyder
  • 👤 Prithipal Singh

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-29 11:42
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/94; G01N33/9446; Y; Y10; Y10S; Y10S435/00; Y10S435/961

Claims Analysis

Total Claims: 2
Claim 1
Independent Claim 60 words
Antibodies prepared in response to an antigen of the formula: ##STR4## wherein: R is a saturated aliphatic linking group of from 2 to 6 carbon atoms having from 0 to 1 oxo-carboxyl groups at its terminus bonded to nitrogen; Y 1 is a poly(amino acid); and n 1 is one to the molecular weight of Y 1 divided by 2000.
Claim 2
Dependent Claim 60 words
Antibodies prepared in response to an antigen of the formula: ##STR4## wherein: R is a saturated aliphatic linking group of from 2 to 6 carbon atoms having from 0 to 1 oxo-carboxyl groups at its terminus bonded to nitrogen; Y 1 is a poly(amino acid); and n 1 is one to the molecular weight of Y 1 divided by 2000.

References Cited (Backward Citations)

US2483884A Cited
US2483885A Cited
US2538764A Cited
US2686788A Cited
US3592949A Cited
US3817837A Cited
US4214001A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-08-25 1990-02-24 1990-08-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-08-25 1994-02-24 1994-08-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-08-25 1998-02-24 1998-08-26 $7700.00 Window Closed / Lapsed

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