US4608248A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for time-controlled release of active ingredients
Assignee: Warner Lambert Co LLC
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Filing: 1986-02-24
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Granted: 1986-08-26
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Expires: 2006-02-24
Abstract
Abstract The present invention provides a process for the timed control of the liberation of active material from a retarded active material-containing composition by the addition of a hydrophilic polymer, wherein the rate of liberation is adjusted by means of the viscosity of the added hydrophilic polymer, the rate of liberation increasing with increasing viscosity.
Inventors
- 👤 Adolf Knecht
- 👤 Helmut Augart
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 16:53
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2013; A61K9/2022; A61K9/205; A61K9/2054
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
60 words
In a process for controlling the timed release of active material from a retarded active material composition containing polysoluble adjuvant materials which is melt granulated, pressed and tableted, wherein the improvement comprises increasing the rate of release of active material by homogeneously admixing therewith prior to melt-granulating methylcellulose or carboxymethylcellulose at an increasing viscosity of from 0.02 to 40 pa.s.
Claim 2
Dependent Claim
60 words
In a process for controlling the timed release of active material from a retarded active material composition containing polysoluble adjuvant materials which is melt granulated, pressed and tableted, wherein the improvement comprises increasing the rate of release of active material by homogeneously admixing therewith prior to melt-granulating methylcellulose or carboxymethylcellulose at an increasing viscosity of from 0.02 to 40 pa.s.
Claim 3
Dependent Claim
66 words
In a process for controlling the timed release of active material from a retarded active material composition containing castor oil, stearic acid and lactose which is melt granulated, pressed and tableted, wherein the improvement comprises adjusting the rate of release of active material by homogeneously admixing therewith prior to melt granulating carboxy methylcellulose at viscosity stages of 0.05, 0.3, 0.6, 3, 6, 20 or 40 Pa.s.
Claim 4
Dependent Claim
66 words
In a process for controlling the timed release of active material from a retarded active material composition containing castor oil, stearic acid and lactose which is melt granulated, pressed and tableted, wherein the improvement comprises adjusting the rate of release of active material by homogeneously admixing therewith prior to melt granulating carboxy methylcellulose at viscosity stages of 0.05, 0.3, 0.6, 3, 6, 20 or 40 Pa.s.
References Cited (Backward Citations)
US2805977A
Cited
US2875130A
Cited
US3402240A
Cited
US3062720A
Cited
US3065143A
Cited
US3108046A
Cited
US3133863A
Cited
US3279998A
Cited
US3147187A
Cited
US3577514A
Cited
US3689674A
Cited
US4167558A
Cited
EP0068446A2
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-08-25 | 1990-02-24 | 1990-08-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-08-25 | 1994-02-24 | 1994-08-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-08-25 | 1998-02-24 | 1998-08-26 | $7700.00 | Window Closed / Lapsed |