US4607163A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for coupling a liquid chromatograph and a mass spectrometer
Assignee: Jeol Ltd
•
Filing: 1984-12-14
•
Granted: 1986-08-19
•
Expires: 2004-12-14
Abstract
Abstract An instrument combining a mass spectrometer with a liquid chromatograph has a low-pressure chamber that is evacuated by an evacuating equipment, an exit nozzle for allowing the effluent from the chromatograph to be ejected as a jet into the low-pressure chamber, and a connecting passage for conveying the jet of the effluent from the nozzle into the ionization chamber of the mass spectrometer, to stably supply the effluent from the chromatograph as the sample for the ion source into the ionization chamber. The instrument is further provided with a means for producing a flow of gas which moves along the inner walls of the low-pressure chamber and the connecting passage in such a way that the jet of the effluent is enveloped in the gas flow.
Inventors
- 👤 Tokuo Mizuno
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 15:23
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/62; G01N30/72; G01N30/7233; G01N30/7273; G01N30/26; G01N30/38
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
124 words
A device for coupling a liquid chromatograph and a mass spectrometer comprising a low-pressure chamber in communication with means for evacuating the chamber, an exit nozzle opening into said chamber for ejecting the effluent from the chromatograph as a jet, a connecting passage opening into said chamber for conveying the jet of the effluent emitted from the nozzle into the ionization chamber of the mass spectrometer, and a means for producing a flow of gas which moves along the inner walls of the low-pressure chamber in the vicinity of the connecting passage and along the walls of the connecting passage in such a way that the jet of the effluent is enveloped in the gas flow and the effluent does not contact the walls.
Claim 2
Independent Claim
124 words
A device for coupling a liquid chromatograph and a mass spectrometer comprising a low-pressure chamber in communication with means for evacuating the chamber, an exit nozzle opening into said chamber for ejecting the effluent from the chromatograph as a jet, a connecting passage opening into said chamber for conveying the jet of the effluent emitted from the nozzle into the ionization chamber of the mass spectrometer, and a means for producing a flow of gas which moves along the inner walls of the low-pressure chamber in the vicinity of the connecting passage and along the walls of the connecting passage in such a way that the jet of the effluent is enveloped in the gas flow and the effluent does not contact the walls.
Claim 3
Dependent Claim
17 words
The device of claim 1 wherein the means for producing the gas flow comprises an annular nozzle.
Claim 4
Dependent Claim
25 words
The device of claim 1 wherein the means for producing the gas flow comprises a nozzle consisting of a plurality of thin pipes arranged annularly.
Claim 5
Dependent Claim
18 words
The device of claim 1 wherein the low-pressure chamber is directly evacuated by a vacuum pump provided independently.
Claim 6
Dependent Claim
35 words
The device of claim 1 wherein the low-pressure chamber is evacuated by the evacuating pump for the ion source of the mass spectrometer and is in communication with this evacuating pump via the connecting passage.
Claim 7
Dependent Claim
28 words
The device of claim 1 wherein the gas of the flow produced by the gas flow producing means is the source of the reactant gas for chemical ionization.
Claim 8
Dependent Claim
18 words
the device of claim 6 wherein the gas is the source of NH 3 or CH 4 .
Claim 9
Dependent Claim
22 words
The device of claim 1 wherein the low-pressure chamber has an inner surface that tapers to the opening of the connecting passage.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-08-18 | 1990-02-17 | 1990-08-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-08-18 | 1994-02-17 | 1994-08-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-08-18 | 1998-02-17 | 1998-08-19 | $7700.00 | Window Closed / Lapsed |