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US4605629A Expired / Lapsed US ⏱️ 0.0 years remaining

Method of eluting reagent from reagent strips for chemical analyses and reagent strip therefor

Assignee: Roche Diagnostics GmbH
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Filing: 1984-07-27
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Granted: 1986-08-12
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Expires: 2004-07-27
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Abstract

Abstract The present invention provides a method of improving reagent elution from a reagent strip comprising a handle on one end which is affixed an absorbent carrier impregnated with a reagent. The absorbent carrier is pressed against the handle by a thin mesh which is stuck or sealed on to the handle on opposite sides of the carrier. Another mesh is between the carrier and the handle. When the carrier is immersed in a liquid, the meshes improve the elution of the reagent into the liquid.

Inventors

  • 👤 Hans Lange
  • 👤 Edda Geisler
  • 👤 Wolfgang Werner

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 00:06
CPC Classifications
G; G01; G01N; G01N31/00; G01N31/22; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/525; Y; Y10; Y10S; Y10S435/00; Y10S435/805

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 103 words
A method of reagent elution from a reagent strip having an elongated handle and a dry, absorbent carrier impregnated with a reagent on one end of the handle, the method comprising: providing a thin mesh stuck onto the handle at opposite sides of the absorbent carrier, substantially covering the absorbent carrier, and pressing the absorbent carrier toward the handle and another mesh between the handle and the absorbent carrier for improving the quantitative elution and the rate of elution of the reagent into a liquid when the absorbent carrier is immersed therein; and immersing the absorbent carrier in the liquid for the elution.
Claim 2
Independent Claim 103 words
A method of reagent elution from a reagent strip having an elongated handle and a dry, absorbent carrier impregnated with a reagent on one end of the handle, the method comprising: providing a thin mesh stuck onto the handle at opposite sides of the absorbent carrier, substantially covering the absorbent carrier, and pressing the absorbent carrier toward the handle and another mesh between the handle and the absorbent carrier for improving the quantitative elution and the rate of elution of the reagent into a liquid when the absorbent carrier is immersed therein; and immersing the absorbent carrier in the liquid for the elution.
Claim 3
Dependent Claim 43 words
The method of claim 1, and further comprising: making the handle and the mesh of synthetic resin and the absorbent carrier of fleece or paper of at least one material selected from the group consisting of cotton, cellulose, regenerated cellulose, polyamide, and polyester.
Claim 4
Dependent Claim 15 words
The method of claim 1, wherein the liquid comprises only an appropriate solvent or diluent.
Claim 5
Dependent Claim 60 words
The method of claim 1 for the analysis of a test material, comprising: after immersing the absorbent carrier in the liquid into which the reagent therein elutes, combining at least part of each of the liquid and test material; and detecting any physio-chemical change in the combined liquid and test material thereby effected for the analysis of the test material.
Claim 6
Dependent Claim 32 words
The method of claim 1 wherein the liquid is a test liquid, and further comprising: detecting any physio-chemical change in the test liquid thereby effected for the analysis of the test liquid.
Claim 7
Dependent Claim 40 words
The method of claim 1, wherein providing the other mesh comprises providing the same with a mesh size in the range of from about 80μ to about 250μ and a mesh filament thickness of from about 10μ to about 50μ.
Claim 8
Dependent Claim 28 words
The method of claim 6, wherein providing the other mesh comprises providing the same with a mesh size in the range of from about 100μ to about 200μ.
Claim 9
Dependent Claim 27 words
The method of claim 1, and additionally comprising: providing at least one more such absorbent carrier and meshes on the handle spaced side-by-side with the first-mentioned one.
Claim 10
Dependent Claim 31 words
The method of claim 1, and additionally comprising: providing at least one more absorbent carrier under the thin mesh in sandwich-like fashion with the first-mentioned absorbent carrier, one overlying the other.
Claim 11
Dependent Claim 18 words
The method of claim 8 or 9, and further comprising: providing the absorbent carriers respectively with different reagents.
Claim 12
Dependent Claim 17 words
The method of claim 9, and additionally comprising: providing an intermediate mesh between the overlying absorbent carriers.
Claim 13
Dependent Claim 36 words
The method of claim 11, and further comprising: providing the intermediate mesh with a mesh size in the range of from 80μ to about 250μ and a mesh filament thickness of from 10μ to about 50μ.
Claim 14
Dependent Claim 26 words
The method of claim 12, and further comprising: providing the other mesh with a mesh size in the range of from about 100μ to about 200μ.
Claim 15
Dependent Claim 88 words
In a reagent strip having an elongated handle and a dry, absorbent carrier impregnated with a reagent on one end of the handle, the improvement comprising: means comprising a thin mesh stuck onto the handle at opposite sides of the absorbent carrier, substantially covering the absorbent carrier, and pressing the absorbent carrier toward the handle; and means comprising another mesh between the handle and the absorbent carrier for improving the quantitative elution and the rate of the elution into the liquid when the absorbent carrier is immersed therein.
Claim 16
Dependent Claim 88 words
In a reagent strip having an elongated handle and a dry, absorbent carrier impregnated with a reagent on one end of the handle, the improvement comprising: means comprising a thin mesh stuck onto the handle at opposite sides of the absorbent carrier, substantially covering the absorbent carrier, and pressing the absorbent carrier toward the handle; and means comprising another mesh between the handle and the absorbent carrier for improving the quantitative elution and the rate of the elution into the liquid when the absorbent carrier is immersed therein.

References Cited (Backward Citations)

US3802842A Cited
GB1349623A Cited
US3912655A Cited
US4061468A Cited
US4233089A Cited
US4219334A Cited
US4193766A Cited
US4234316A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-08-11 1990-02-10 1990-08-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-08-11 1994-02-10 1994-08-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-08-11 1998-02-10 1998-08-12 $7700.00 Window Closed / Lapsed

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