US4604472A
Expired / Lapsed
US
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Octahydronaphthalene derivatives and their preparation
Assignee: Sankyo Co Ltd
•
Filing: 1985-07-09
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Granted: 1986-08-05
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Expires: 2005-07-09
Abstract
Abstract Compounds of formula (I): ##STR1## [wherein X represents a hydrogen atom or a 2-methylbutyryl group, Y represents a hydrogen atom or a methyl group and R 1 and R 2 are the same or different and each represents an oxygen atom or a group of formula ═N--OR 3 (wherein R 3 represents a hydrogen atom or an alkyl group)], the free hydroxy-carboxylic acids corresponding thereto and salts and esters of said acids may be prepared by oxidizing and, if necessary, oximating a corresponding ML-236A, ML-236B, MB-530A or MB-530B compound, and these compounds have valuable antihypercholesteraemic activity.
Inventors
- 👤 Junya Ide
- 👤 Shigeki Muramatsu
- 👤 Yoshio Tsujita
- 👤 Masao Kuroda
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 03:05
CPC Classifications
C; C07; C07C; C07C65/00; C07C65/01; C07C59/00; C07C59/40; C07C59/76; C07C59/90; A; A61; A61P; A61P3/00; A61P3/06; C07D; C07D309/00; C07D309/16; C07D309/28; C07D309/30; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/18; C07F7/1804; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55
Claims Analysis
Total Claims: 32
Claim 1
Independent Claim
40 words
The compounds of the formula: ##STR17## wherein: X is a hydrogen atom or a 2-methylbutyryl group; Y is a hydrogen atom or a methyl group; and R 3 is a hydrogen atom or an alkyl group having 1-6 carbon atoms.
Claim 2
Dependent Claim
40 words
The compounds of the formula: ##STR17## wherein: X is a hydrogen atom or a 2-methylbutyryl group; Y is a hydrogen atom or a methyl group; and R 3 is a hydrogen atom or an alkyl group having 1-6 carbon atoms.
Claim 3
Dependent Claim
9 words
The compounds of claim 1 wherein Y is hydrogen.
Claim 4
Dependent Claim
10 words
The compounds of claim 1 wherein Y is methyl group.
Claim 5
Dependent Claim
9 words
The compounds of claim 2 wherein X is hydrogen.
Claim 6
Dependent Claim
11 words
The compounds of claim 2 wherein X is a 2-methylbutyryl group.
Claim 7
Dependent Claim
9 words
The compounds of claim 3 wherein X is hydrogen.
Claim 8
Dependent Claim
11 words
The compounds of claim 3 wherein X is a 2-methylbutyryl group.
Claim 9
Dependent Claim
10 words
The compounds of claim 2 wherein R 3 is hydrogen.
Claim 10
Dependent Claim
10 words
The compounds of claim 3 wherein R 3 is hydrogen.
Claim 11
Dependent Claim
10 words
The compounds of claim 4 wherein R 3 is hydrogen.
Claim 12
Dependent Claim
10 words
The compounds of claim 5 wherein R 3 is hydrogen.
Claim 13
Dependent Claim
10 words
The compounds of claim 6 wherein R 3 is hydrogen.
Claim 14
Dependent Claim
10 words
The compounds of claim 7 wherein R 3 is hydrogen.
Claim 15
Dependent Claim
17 words
The compounds of claim 2 wherein R 3 is a lower alkyl group having 1-6 carbon atoms.
Claim 16
Dependent Claim
17 words
The compounds of claim 3 wherein R 3 is a lower alkyl group having 1-4 carbon atoms.
Claim 17
Dependent Claim
17 words
The compounds of claim 4 wherein R 3 is a lower alkyl group having 1-4 carbon atoms.
Claim 18
Dependent Claim
17 words
The compounds of claim 5 wherein R 3 is a lower alkyl group having 1-4 carbon atoms.
Claim 19
Dependent Claim
17 words
The compounds of claim 6 wherein R 3 is a lower alkyl group having 1-4 carbon atoms.
Claim 20
Dependent Claim
17 words
The compounds of claim 7 wherein R 3 is a lower alkyl group having 1-4 carbon atoms.
Claim 21
Dependent Claim
12 words
The compounds of claim 2 wherin R 3 is a methyl group.
Claim 22
Dependent Claim
12 words
The compounds of claim 3 wherein R 3 is a methyl group.
Claim 23
Dependent Claim
12 words
The compounds of claim 4 wherein R 3 is a methyl group.
Claim 24
Dependent Claim
12 words
The compounds of claim 5 wherein R 3 is a methyl group.
Claim 25
Dependent Claim
12 words
The compounds of claim 6 wherein R 3 is a methyl group.
Claim 26
Dependent Claim
12 words
The compounds of claim 7 wherein R 3 is a methyl group.
Claim 27
Dependent Claim
12 words
The compounds of claim 2 wherein R 3 is an ethyl group.
Claim 28
Dependent Claim
12 words
The compounds of claim 3 wherein R 3 is an ethyl group.
Claim 29
Dependent Claim
12 words
The compounds of claim 4 wherein R 3 is an ethyl group.
Claim 30
Dependent Claim
12 words
The compounds of claim 5 wherein R 3 is an ethyl group.
Claim 31
Dependent Claim
12 words
The compounds of claim 6 wherein R 3 is an ethyl group.
Claim 32
Dependent Claim
12 words
The compounds of claim 7 wherein R 3 is an ethyl group.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-08-04 | 1990-02-03 | 1990-08-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-08-04 | 1994-02-03 | 1994-08-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-08-04 | 1998-02-03 | 1998-08-05 | $7700.00 | Window Closed / Lapsed |