US4599232A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical composition with metabolic and energetic activity for the use in cardiac and vascular therapy
Assignee: Sigma Tau Industrie Farmaceutiche Riunite SpA
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Filing: 1984-02-09
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Granted: 1986-07-08
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Expires: 2004-02-09
Abstract
Abstract The invention relates to a pharmaceutical composition containing carnitine or acetylcarnitine and Coenzyme Q 10 in ratios from 100:1 to 2:1, together with pharmaceutically acceptable eccipients. The pharmaceutical composition described is suitable for the treatment of tissue energetic and metabolic disorders, and especially of heart and blood vessels, occurring in atherosclerosis, in myocardial or coronaric insufficiency, in hypertension, in cerebral ischaemia and, in general, tissue anoxia.
Inventors
- 👤 Alberto Bertelli
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 02:08
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/205; A61P; A61P43/00; A61P9/00; A61P9/10; A61P9/12
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
52 words
A pharmaceutical composition having metabolic antianoxic activity containing as the principal active ingredient an antianoxic effective amount of a combination comprising the components Coenzyme Q 10 and a quaternary ammonium compound selected from carnitine and acetylcarnitine in admixture with a pharmaceutically acceptable carrier, said components being in a synergistic antianoxic active ratio.
Claim 2
Dependent Claim
52 words
A pharmaceutical composition having metabolic antianoxic activity containing as the principal active ingredient an antianoxic effective amount of a combination comprising the components Coenzyme Q 10 and a quaternary ammonium compound selected from carnitine and acetylcarnitine in admixture with a pharmaceutically acceptable carrier, said components being in a synergistic antianoxic active ratio.
Claim 3
Dependent Claim
30 words
A pharmaceutical composition according to claim 1 in which the Coenzyme Q 10 and the quaternary ammonium compound are in a ratio of from 1:100 to 1:2 parts by weight.
Claim 4
Dependent Claim
17 words
A pharmaceutical composition according to claim 2 in which the quaternary ammonium compound is carnitine in L-form.
Claim 5
Dependent Claim
15 words
A pharmaceutical composition according to claim 2 in which the quaternary ammonium compound is acetyl-L-carnitine.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-07-07 | 1990-01-06 | 1990-07-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-07-07 | 1994-01-06 | 1994-07-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-07-07 | 1998-01-06 | 1998-07-08 | $7700.00 | Window Closed / Lapsed |