Abstract A novel compound, and stable compositions thereof for the effective, nonirritating treatment of microbial colonization are disclosed. The compound is used for the topical treatment of affected areas as well as for control of certain diarrheas. The compound is the ozonide of the liquid wax jojoba oil. The ozonide material of the present invention has the ability to release nascent oxygen directly to locales to at least inhibit the microorganisms without the characteristic dryness and skin irritation associated with previous benzoyl peroxide treatments. The compositions are stable, in contrast to the limited shelf-stability of the previously used benzoyl peroxide formulation. This ozonide and products containing same have no tendency to become rancid, which is a problem with other ozonides.
Inventors
👤 Richard L. De Villez
Bibliographic Details
Application Number—
JurisdictionUS
Data Sourcegoogle_patents
Last Synchronized2026-11-03 17:21
CPC Classifications
C; C07; C07D; C07D323/00; C07D323/02
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
9 words
Jojoba ozonide of refractive index n 46 ° =1.4540.
Claim 2
Dependent Claim
9 words
Jojoba ozonide of refractive index n 46 ° =1.4540.
Claim 3
Dependent Claim
20 words
The jojoba ozonide according to claim 1 dissolved in anhydrous jojoba oil, its anhydrous isomers and/or hydrogenates or mixtures thereof.
Claim 4
Dependent Claim
24 words
Composition for the control of microbial infections which comprise an effective amount of the jojoba ozonide according to claim 1 in an anhydrous vehicle.
Claim 5
Dependent Claim
13 words
Composition according to claim 3 containing at least 0.1% of the jojoba ozonide.
Claim 6
Dependent Claim
32 words
Composition according to claim 3 for the control of topical conditions caused by microbial colonization which comprises control-effective amounts of jojoba ozonide in the range 0.5% to 11.8wt.% O 3 (by iodometry).
Claim 7
Dependent Claim
35 words
The composition according to claim 4 wherein said vehicle includes an anhydrous diluent for said jojoba ozonide selected from the group consisting of jojoba oil, transisomerized jojoba oil, hydrogenated jojoba oil and isomorphous mixtures thereof.
Claim 8
Dependent Claim
22 words
The composition according to claim 5 wherein the concentration of said jojoba ozonide is in the range 2-10 wt.% O 3 .
Claim 9
Dependent Claim
28 words
The method for treating topical microbial infections which comprises the step of applying topically to an affected area an effective amount of a composition according to claim 3.