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US4586190A Expired / Lapsed US ⏱️ 0.0 years remaining

Blood cell discriminator and counter utilizing transmitted and scattered light

Assignee: Shimadzu Corp
•
Filing: 1983-11-14
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Granted: 1986-04-29
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Expires: 2003-11-14
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Abstract

Abstract A blood counter comprising a sheathed flow cell; a light source including what has the wavelengths causing absorption of light by hemoglobin in the blood; means for receiving transmitted light; means for receiving the scattered light; a decision assembly for judging, based on the output signals detected by means for receiving the transmitted light and scattered light, (i) the flowing cells therein to be a red blood cell if the degree of absorption is larger than the preselected level and (ii) the other to be a blood platelet if the intensity of the scattered light is larger than a certain level and if the degree of absorption is smaller than said preselected level; and a counter assembly for counting out the red blood cells and blood platelets.

Inventors

  • 👤 Fumio Tsuji

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 22:11
CPC Classifications
G; G01; G01N; G01N15/00; G01N15/10; G01N15/14; G01N15/1456; G01N15/1459; G01N33/00; G01N33/48; G01N15/01; G01N2015/012

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 207 words
A blood counter comprising a sheathed flow cell in which each particle of the cells of blood is flowed separately and succesively; a light source for radiating light on said sheathed flow cell, the light including light having the wavelengths for causing absorption of light by hemoglobin in the blood; a portion of said light being transmitted across said sheathed flow cell; a portion of said light being scattered from the sheathed flow cell, means for receiving transmitted light to detect the degree of absorption by hemoglobin from the light transmitted across said sheathed flow cell; means for receiving the scattered light to detect the intensity of the light scattered from the sheathed flow cell; a decision assembly for judging, based on the output signals detected by means for receiving the transmitted light and scattered light, (1) the flowing cells therein to be a red blood cell if the degree of absorption is larger than the preselected level and (11) the other material to be a blood platelet if the intensity of the scattered light is larger than a certain level and if the degree of absorption is smaller than said preselected level; and a counter assembly for counting out the red blood cells and blood platelets.
Claim 2
Dependent Claim 207 words
A blood counter comprising a sheathed flow cell in which each particle of the cells of blood is flowed separately and succesively; a light source for radiating light on said sheathed flow cell, the light including light having the wavelengths for causing absorption of light by hemoglobin in the blood; a portion of said light being transmitted across said sheathed flow cell; a portion of said light being scattered from the sheathed flow cell, means for receiving transmitted light to detect the degree of absorption by hemoglobin from the light transmitted across said sheathed flow cell; means for receiving the scattered light to detect the intensity of the light scattered from the sheathed flow cell; a decision assembly for judging, based on the output signals detected by means for receiving the transmitted light and scattered light, (1) the flowing cells therein to be a red blood cell if the degree of absorption is larger than the preselected level and (11) the other material to be a blood platelet if the intensity of the scattered light is larger than a certain level and if the degree of absorption is smaller than said preselected level; and a counter assembly for counting out the red blood cells and blood platelets.
Claim 3
Dependent Claim 32 words
A blood counter as claimed in claim 1, wherein said light source radiates light including what has a wavelength of 415 nm as the light causing hemoglobin in blood to absorb it.
Claim 4
Dependent Claim 16 words
A blood counter as claimed in claim 1, wherein said light source is a white one.
Claim 5
Dependent Claim 24 words
A blood counter as claimed in claim 1, wherein said means for receiving the transmitted light comprises an interference filter and a photomultiplier tube.
Claim 6
Dependent Claim 32 words
A blood counter as claimed in claim 1, wherein said means for receiving the scattered light comprises a doughnut mirror and a photomultiplier tube receiving the scattered light reflected by said mirror.
Claim 7
Dependent Claim 18 words
A blood counter as claimed in claim 1, wherein said decision and counter assemblies comprise a microcomputer system.

References Cited (Backward Citations)

US2875666A Cited
US3827805A Cited
US4027973A Cited
EP0009307A1 Cited
JPS58131542A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-04-28 1989-10-28 1990-04-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-04-28 1993-10-28 1994-04-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-04-28 1997-10-28 1998-04-29 $7700.00 Window Closed / Lapsed

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