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US4585585A Expired / Lapsed US ⏱️ 0.0 years remaining

Decapeptides produced from bioadhesive polyphenolic proteins

Assignee: CONNECTICUT RESEARCH AND DEVELOPMENT CORP A CORP OF CT, University of
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Filing: 1984-03-07
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Granted: 1986-04-29
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Expires: 2004-03-07
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Abstract

Abstract Methods are described for the preparation and isolation of novel decapeptides of the formula: ##STR1## wherein each X is independently selected from the group comprising hydroxyl and hydrogen, wherein each R is independently selected from the group comprising hydrogen and methyl, from bioadhesive polyphenolic proteins which comprise: ##STR2## wherein n is a whole number from about 60 to about 100, wherein each X is independently selected from the group comprising hydroxyl and hydrogen, and wherein each R is independently selected from the group comprising hydrogen and methyl. Such decapeptides may be used to construct large polyphenolic molecules comprising from about 1 to about 1000 decapeptide repeating units and wherein the linking group is selected from the group comprising amino acid, oligopeptide and bifunctional spacer.

Inventors

  • 👤 J. Herbert Waite

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 13:42
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; A; A61; A61K; A61K38/00

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 32 words
Decapeptides of the formula: ##STR10## wherein each X is independently selected from the group comprising hydroxyl and hydrogen and wherein each R is independently selected from the group comprising hydrogen and methyl.
Claim 2
Dependent Claim 32 words
Decapeptides of the formula: ##STR10## wherein each X is independently selected from the group comprising hydroxyl and hydrogen and wherein each R is independently selected from the group comprising hydrogen and methyl.
Claim 3
Dependent Claim 65 words
Polyphenolic molecules which comprise from about 1 to about 1000 repeating units of the formula: ##STR11## wherein each X is independently selected from the group comprising hydroxyl and hydrogen and wherein each R is independently selected from the group comprising hydrogen and methyl, and wherein the repeating units are linked with a linking group selected from the group comprising amino acid, oligopeptide and bifunctional spacer.
Claim 4
Dependent Claim 65 words
Polyphenolic molecules which comprise from about 1 to about 1000 repeating units of the formula: ##STR11## wherein each X is independently selected from the group comprising hydroxyl and hydrogen and wherein each R is independently selected from the group comprising hydrogen and methyl, and wherein the repeating units are linked with a linking group selected from the group comprising amino acid, oligopeptide and bifunctional spacer.
Claim 5
Dependent Claim 13 words
A composition as claimed in claim 2, wherein the linking group is glutaraldehyde.

References Cited (Backward Citations)

US4302386A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-04-28 1989-10-28 1990-04-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-04-28 1993-10-28 1994-04-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-04-28 1997-10-28 1998-04-29 $7700.00 Window Closed / Lapsed

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