US4579854A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bronchodilating 8-hydroxy-5-{(1R)-1-hydroxy-2-[N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)-amino]ethyl} carbostyril
Assignee: Tanabe Pharma Corp
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Filing: 1984-12-21
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Granted: 1986-04-01
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Expires: 2004-12-21
Abstract
Abstract A novel carbostyril derivative of the formula: <IMAGE> (I) or a pharmaceutically acceptable acid addition salt thereof, and a process for preparing same. The compound (I) shows potent bronchodilating activity and is useful as a bronchodilator.
Inventors
- 👤 Takeo Iwakuma
- 👤 Akira Tsunashima
- 👤 Katsuo Ikezawa
- 👤 Osasi Takaiti
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 03:50
CPC Classifications
C; C07; C07D; C07D215/00; C07D215/02; C07D215/16; C07D215/20; C07D215/24; C07D215/26; A; A61; A61P; A61P11/00; A61P11/08; A61P25/00; A61P25/02; C07D207/00; C07D207/46; C07D207/48; C07D215/58; C07D215/60; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
15 words
A carbostyril compound of the formula: ##STR15## or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
15 words
A carbostyril compound of the formula: ##STR15## or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
21 words
The compound of claim 1 which is a mixture of 8-hydroxy-5-{(1R)-1-hydroxy-2-[N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)amino]ethyl}carbostyril and 8-hydroxy-5-{(1S)-1-hydroxy-2-[N-((1S)-2-(p-methoxyphenyl)-1-methylethyl)amino]ethyl}carbostyril, or a pharmaceutically acceptable acid addition salt thereof.
Claim 4
Dependent Claim
16 words
The compound of claim 1 which is 8-hydroxy-5-{(1R)-1-hydroxy-2-[N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)amino]ethyl}carbostyril or a pharmaceutically acceptable acid addition salt thereof.
Claim 5
Dependent Claim
31 words
A pharmaceutical composition which comprises a therapeutically effective amount of a bronchodilating compound of the formula: ##STR16## or a pharmaceutically acceptable acid addition salt thereof, and a pharmaceutically acceptable carrier therefor.
Claim 6
Dependent Claim
31 words
A pharmaceutical composition which comprises a therapeutically effective amount of a bronchodilating compound of the formula: ##STR16## or a pharmaceutically acceptable acid addition salt thereof, and a pharmaceutically acceptable carrier therefor.
Claim 7
Independent Claim
35 words
A method of producing a bronchodilating effect on a warm-blooded animal comprising administering to said warm-blooded animal an effective amount of a compound of the formula: ##STR17## or a pharmaceutically acceptable acid addition salt thereof.
Claim 8
Independent Claim
35 words
A method of producing a bronchodilating effect on a warm-blooded animal comprising administering to said warm-blooded animal an effective amount of a compound of the formula: ##STR17## or a pharmaceutically acceptable acid addition salt thereof.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-03-31 | 1989-09-30 | 1990-04-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-03-31 | 1993-09-30 | 1994-04-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-03-31 | 1997-09-30 | 1998-04-01 | $7700.00 | Window Closed / Lapsed |