US4575457A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Periodontal toothpaste with wound-healing properties
Assignee: Colgate Palmolive Co
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Filing: 1984-05-24
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Granted: 1986-03-11
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Expires: 2004-05-24
Abstract
Abstract Pharmaceutical composition of skin respiratory factor (SRF), sodium chloride, bicarbonate, fluoride and zinc chloride in a suitable toothpaste vehicle provides effective therapy for gingivitis when brushed on the teeth and gingivae. Pharmaceutical composition of SRF in a viscous composition suitable for application to the gingivae and effective over an extended period of time for healing tissue damaged by gingevitis. A toothpaste tube for packaging a pharmaceutical composition of SRF, sodium chloride, bicarbonate, fluoride and zinc chloride.
Inventors
- 👤 Sanford S. Mazarin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 22:14
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/21; A61K8/27; A61K8/30; A61K8/64; A61K8/66; A61K8/96; A61K8/97; A61K8/9728; A61Q; A61Q11/00; B; B65; B65D; B65D35/00; B65D35/24; B65D35/242
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
83 words
A pharmaceutical composition comprising skin respiratory factor (SRF), sodium chloride, and bicarbonate, fluoride, and zinc ions in a suitable toothpaste vehicle, wherein the range of SRF present is from 2700 to 3300 units per oz., total fluoride is present in the range 900 to 1100 ppm, bicarbonate ion is present in the range 13.05 to 20.00% by weight, sodium chloride is present in the range 4.50 to 10.5% by weight and zinc ion is present in the range 0.108 to 0.132% by weight.
Claim 2
Dependent Claim
83 words
A pharmaceutical composition comprising skin respiratory factor (SRF), sodium chloride, and bicarbonate, fluoride, and zinc ions in a suitable toothpaste vehicle, wherein the range of SRF present is from 2700 to 3300 units per oz., total fluoride is present in the range 900 to 1100 ppm, bicarbonate ion is present in the range 13.05 to 20.00% by weight, sodium chloride is present in the range 4.50 to 10.5% by weight and zinc ion is present in the range 0.108 to 0.132% by weight.
Claim 3
Dependent Claim
35 words
A pharmaceutical composition according to claim 1 wherein the zinc ion is in the form of a salt selected from the group consisting of zinc chloride, zinc citrate, zinc acetate, zinc lactate, and zinc salicylate.
Claim 4
Dependent Claim
38 words
A pharmaceutical composition according to claim 1 comprising about 1.23% by weight SRF, 10% by weight sodium chloride, 15% by weight sodium bicarbonate, 0.22% by weight sodium fluoride, 0.25% by weight zinc chloride in a suitable toothpaste vehicle.
Claim 5
Dependent Claim
42 words
Method of treating gingivitis by administering to the oral cavity of a human suffering from gingivitis, a pharmaceutical composition in accordance with claim 1 comprising skin respiratory factor (SRF), sodium chloride, and bicarbonate, fluoride and zinc ions in a suitable toothpaste vehicle.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-03-10 | 1989-09-09 | 1990-03-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-03-10 | 1993-09-09 | 1994-03-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-03-10 | 1997-09-09 | 1998-03-11 | $7700.00 | Window Closed / Lapsed |