US4563275A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Chromatography column and end plug assembly
Assignee: Bio Rad Laboratories Inc
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Filing: 1984-08-01
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Granted: 1986-01-07
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Expires: 2004-08-01
Abstract
Abstract A novel column cartridge for a chromatography apparatus, particularly HPLC, is comprised of a hollow metal tube, open at both ends and having internal shoulders facing each open end, and a pair of end plugs each having a frusto-conical shape at its outer end. The end plugs are sealed into place by rolling the tube end to compress it against the frustum surface, leaving a short length of plug extending beyond the tube end for compression sealing against a conventional holder or mounting device.
Inventors
- 👤 Dan L. McEachern
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 06:04
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/60; G01N30/6091; B; B01; B01D; B01D15/00; B01D15/08; B01D15/10; B01D15/22; G01N30/50; G01N30/56; G01N30/6004; G01N30/6026; G01N30/6034
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
94 words
A chromatographic column cartridge comprising: a cylindrical tube of formable metal having open ends and a pair of shoulders extending around the internal circumference thereof, one shoulder facing each said end; and a pair of resilient seal plugs shaped to fit inside said tube ends and to rest on said shoulders, each said plug containing a longitudinal passage communicating the exposed end surface thereof with the interior of said tube, the outer terminal portion of each said plug having the form of a frustum tapering outward, extending across and terminating beyond said tube end.
Claim 2
Dependent Claim
94 words
A chromatographic column cartridge comprising: a cylindrical tube of formable metal having open ends and a pair of shoulders extending around the internal circumference thereof, one shoulder facing each said end; and a pair of resilient seal plugs shaped to fit inside said tube ends and to rest on said shoulders, each said plug containing a longitudinal passage communicating the exposed end surface thereof with the interior of said tube, the outer terminal portion of each said plug having the form of a frustum tapering outward, extending across and terminating beyond said tube end.
Claim 3
Dependent Claim
35 words
A cartridge according to claim 1 in which the inner end of said longitudinal passage is widened to accommodate a filter capable of passing a mobile phase while retaining chromatographic packing material in said tube.
Claim 4
Dependent Claim
24 words
A cartridge according to claim 1 in which said plugs are formed of a fluorocarbon polymer and said tube is formed of stainless steel.
Claim 5
Dependent Claim
112 words
A chromatographic column cartridge comprising: a rigid cylindrical tube having open ends and a pair of shoulders extending around the internal circumference thereof, one shoulder facing each said end, and each said end curving inward whereby the diameter of the opening at each end is less than the internal diameter of the portion of said tube between said shoulder and said end; and a pair of resilient seal plugs, one said plug retained at each end of said tube in the space between said shoulder and said opening, each said plug fitting snugly within said space and terminating at its outer end in a frustum tapering outward and protruding through said opening.
Claim 6
Dependent Claim
112 words
A chromatographic column cartridge comprising: a rigid cylindrical tube having open ends and a pair of shoulders extending around the internal circumference thereof, one shoulder facing each said end, and each said end curving inward whereby the diameter of the opening at each end is less than the internal diameter of the portion of said tube between said shoulder and said end; and a pair of resilient seal plugs, one said plug retained at each end of said tube in the space between said shoulder and said opening, each said plug fitting snugly within said space and terminating at its outer end in a frustum tapering outward and protruding through said opening.
Claim 7
Dependent Claim
35 words
A cartridge according to claim 4 in which the inner end of said longitudinal passage is widened to accommodate a filter capable of passing a mobile phase while retaining chromatographic packing material in said tube.
Claim 8
Dependent Claim
24 words
A cartridge according to claim 4 in which said plugs are formed of a fluorocarbon polymer and said tube is formed of stainless steel.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-01-06 | 1989-07-08 | 1990-01-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-01-06 | 1993-07-08 | 1994-01-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-01-06 | 1997-07-08 | 1998-01-07 | $7700.00 | Window Closed / Lapsed |