US4560555A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Reactive polymers for dermal and transdermal therapy
Assignee: Sogimi Srl
•
Filing: 1983-12-12
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Granted: 1985-12-24
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Expires: 2003-12-12
Abstract
Abstract Reactive polymer coatings for the treatment of skin disorders, constituted of cross-linkable polyurethanes, that have film properties, and are suitable to be applied to the skin in need of treatment are generally constituted of two components to be mixed at the usemoment, so that the cross-linkage mostly happens through interaction with the proteic components of the treated skin-parts. These formulations are also good carriers for transdermal action drugs.
Inventors
- 👤 Bruno Snider
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 01:05
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/74; C; C08; C08G; C08G18/00; C08G18/06; C08G18/28; C08G18/40; C08G18/42; C08G18/4288; A61K9/00; A61K9/70; A61K9/7007; A61K9/7023; A61L; A61L26/00; A61L26/0009; A61L26/0019; A61P; A61P17/00; C08G18/30; C08G18/36
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
78 words
A method of treating the human or animal skin comprising forming in situ a polymer film chemically bound to said skin, said film being obtained by coating the skin with a dressing selected from liquid isocyanate prepolymers alone or mixed with prepolymers having free hydroxy, amino or amido groups, together with additives, adjuvants, solvents and transcutaneously acting drugs which are not adversely affected by said liquid isocyanate prepolymers and said prepolymers having free hydroxy, amino or amido groups.
Claim 2
Independent Claim
78 words
A method of treating the human or animal skin comprising forming in situ a polymer film chemically bound to said skin, said film being obtained by coating the skin with a dressing selected from liquid isocyanate prepolymers alone or mixed with prepolymers having free hydroxy, amino or amido groups, together with additives, adjuvants, solvents and transcutaneously acting drugs which are not adversely affected by said liquid isocyanate prepolymers and said prepolymers having free hydroxy, amino or amido groups.
Claim 3
Independent Claim
57 words
A method of providing a protective covering on skin of a human or animal in need of said therapy, comprising; applying to said skin a film-forming polymer composition prepared by mixing immediately prior to application to the skin, a liquid oligomer having reactive hydroxyl, amide or amine groups, and a cross-linkable liquid oligomer having reactive isocyanate groups.
Claim 4
Independent Claim
57 words
A method of providing a protective covering on skin of a human or animal in need of said therapy, comprising; applying to said skin a film-forming polymer composition prepared by mixing immediately prior to application to the skin, a liquid oligomer having reactive hydroxyl, amide or amine groups, and a cross-linkable liquid oligomer having reactive isocyanate groups.
Claim 5
Dependent Claim
28 words
A method according to claim 2 characterized in that said isocyanate prepolymer has a content of free isocyanate (--NCO) groups preferably ranging from about 12% to about 24%.
Claim 6
Dependent Claim
33 words
A method according to claim 2 characterized in that said oligomer having free hydroxy, amino or amido groups is selected from the group consisting of polyesters, polyethers, polyamides hydroxylated polyurethanes, and amino resins.
Claim 7
Dependent Claim
42 words
A method according to claim 4 characterized in that said oligomer having free hydroxy, amino or amido groups has an acidity index from 0.5 to 1, a hydroxy number between about 75 and 140 and a molecular weight between 500 and 2000.
Claim 8
Dependent Claim
31 words
A method according to claim 2, characterized in that the weight ratio between said oligomer having free hydroxy, amino or amido groups and said isocyanate oligomer is from 1:1 and 5:1.
Claim 9
Independent Claim
75 words
A method of treating internal body diseases by coating some skin areas with film-forming polymer compositions, characterized in that cross-linkable liquid isocyanate prepolymers having free isocyanate groups are mixed just before the application with prepolymers having free hydroxy, amino or amido groups and containing effective amounts of transcutaneously-acting systemic drugs which are inert with respect to and not adversely affected by said isocyanate groups, or by said prepolymers having free hydroxy, amino or amido groups.
Claim 10
Independent Claim
75 words
A method of treating internal body diseases by coating some skin areas with film-forming polymer compositions, characterized in that cross-linkable liquid isocyanate prepolymers having free isocyanate groups are mixed just before the application with prepolymers having free hydroxy, amino or amido groups and containing effective amounts of transcutaneously-acting systemic drugs which are inert with respect to and not adversely affected by said isocyanate groups, or by said prepolymers having free hydroxy, amino or amido groups.
References Cited (Backward Citations)
US4250267A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-12-23 | 1989-06-24 | 1989-12-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-12-23 | 1993-06-24 | 1993-12-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-12-23 | 1997-06-24 | 1997-12-24 | $7700.00 | Window Closed / Lapsed |