US4559177A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Quinone derivatives
Assignee: Takeda Pharmaceutical Co Ltd
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Filing: 1980-06-30
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Granted: 1985-12-17
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Expires: 2000-06-30
Abstract
Abstract A compound of the formula: ##STR1## wherein m is an integer of 11 to 22; R 1 is alkyl having 1 to 4 carbon atoms; R 2 is hydrogen, alkyl having 1 to 4 carbon atoms or carboxylic acyl having 1 to 8 carbon atoms. Such compounds have pharmaceutical activities such as hypotensive, tissue metabolism stimulating, immuno-regulatory and lysosomal membrane stabilizing activity, and inhibit SRS-A production, and are useful as a heart failure remedy, cerebral circulation disturbance remedy, immuno-regulator, and antiallergic drug.
Inventors
- 👤 Tetsuya Okutani
- 👤 Giichi Goto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 09:57
CPC Classifications
C; C07; C07C; C07C66/00; C07C41/00; C07C41/01; C07C41/18; C07C41/26; C07C45/00; C07C45/61; C07C45/67; C07C45/673; C07C46/00; C07C46/02; C07C46/06; C07C46/08; C07C50/00; C07C50/26; C07C50/28; C07C59/00; C07C59/40; C07C59/58; C07C59/64; C07C59/76; C07C59/90
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
46 words
A compound of the formula: ##STR14## wherein m is an integer of 11 to 22; R 1 is alkyl having 1 to 4 carbon atoms; and R 2 is hydrogen, alkyl having 1 to 4 carbon atoms or carboxylic acyl having 1 to 8 carbon atoms.
Claim 2
Dependent Claim
46 words
A compound of the formula: ##STR14## wherein m is an integer of 11 to 22; R 1 is alkyl having 1 to 4 carbon atoms; and R 2 is hydrogen, alkyl having 1 to 4 carbon atoms or carboxylic acyl having 1 to 8 carbon atoms.
Claim 3
Dependent Claim
12 words
A compound as claimed in claim 1, wherein R 2 is hydrogen.
Claim 4
Dependent Claim
19 words
A compound as claimed in claim 1, wherein R 2 is carboxylic acyl having 1 to 8 carbon atoms.
Claim 5
Dependent Claim
12 words
A compound as claimed in claim 1, wherein R 1 is methyl.
Claim 6
Dependent Claim
16 words
A compound as claimed in claim 1, wherein m is an integer of 11 to 13.
Claim 7
Dependent Claim
12 words
A compound as claimed in claim 1, wherein the compound is 6-(13-hydroxytridecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone.
Claim 8
Dependent Claim
12 words
A compound as claimed in claim 1, wherein the compound is 6-(22-hydroxydocosyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone.
Claim 9
Dependent Claim
12 words
A compound as claimed in claim 1, wherein the compound is 6-(12-hydroxydodecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone.
Claim 10
Dependent Claim
12 words
A compound as claimed in claim 1, wherein the compound is 6-(11-hydroxyundecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone.
Claim 11
Dependent Claim
12 words
A compound as claimed in claim 1, wherein the compound is 6-(20-hydroxyeicosyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone.
Claim 12
Dependent Claim
12 words
A compound as claimed in claim 1, wherein the compound is 6-(12-acetoxydodecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone.
Claim 13
Dependent Claim
12 words
A compound as claimed in claim 1, wherein the compound is 6-(11-acetoxyundecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone.
Claim 14
Dependent Claim
12 words
A compound as claimed in claim 1, wherein the compound is 6-(18-hydroxyoctadecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone.
References Cited (Backward Citations)
US3658852A
Cited
US3966776A
Cited
US3859317A
Cited
FR2272068A1
Cited
FR2268778A1
Cited
FR2269333A1
Cited
FR2293194A1
Cited
US4139545A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-12-16 | 1989-06-17 | 1989-12-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-12-16 | 1993-06-17 | 1993-12-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-12-16 | 1997-06-17 | 1997-12-17 | $7700.00 | Window Closed / Lapsed |