US4554355A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Heterocyclic compounds as antiallergic agents
Assignee: Wyeth LLC
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Filing: 1984-07-19
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Granted: 1985-11-19
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Expires: 2004-07-19
Abstract
Abstract There are disclosed compounds of the formula ##STR1## wherein X is --O--, --S-- or ##STR2## Y is --CH 2 O--, --OCH 2 --, --CH 2 S--, --SCH 2 --, ##STR3## m is 1-3; A is O or NR 2 ; B is OR 2 ; SR 2 or N(R 2 ) 2 ; R 1 is hydrogen, loweralkyl, loweralkoxy or halo; R 2 is hydrogen or loweralkyl; and the pharmaceutically acceptable salts thereof, and their use in the treatment of leukotriene-mediated naso-bronchial obstructive airpassageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like.
Inventors
- 👤 John H. Musser
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 11:57
CPC Classifications
C; C07; C07D; C07D403/00; C07D403/02; C07D403/12; C07D413/00; C07D413/02; C07D413/12; C07D417/00; C07D417/02; C07D417/12
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
71 words
A compound having the formula ##STR20## wherein X is --O--, --S-- or ##STR21## Y is --CH 2 O--, --OCH 2 --, --CH 2 S--, --SCH 2 --, ##STR22## m is 1-3; A is O or NR 2 ; B is OR 2 , SR 2 or N(R 2 ) 2 ; R 1 is hydrogen, loweralkyl, loweralkoxy or halo; R 2 is hydrogen or loweralkyl; and the pharmaceutically acceptable salts thereof.
Claim 2
Dependent Claim
71 words
A compound having the formula ##STR20## wherein X is --O--, --S-- or ##STR21## Y is --CH 2 O--, --OCH 2 --, --CH 2 S--, --SCH 2 --, ##STR22## m is 1-3; A is O or NR 2 ; B is OR 2 , SR 2 or N(R 2 ) 2 ; R 1 is hydrogen, loweralkyl, loweralkoxy or halo; R 2 is hydrogen or loweralkyl; and the pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim
11 words
The compound of claim 1, which is N-[3-[(2-benzthiazolyl)methoxy]phenyl]pyrrolidin-2-on-4-carboxylic acid, methyl ester.
Claim 4
Dependent Claim
11 words
The compound of claim 1, which is N-[3-[(1-methyl-2-benzimidazolyl)methoxy]phenyl]pyrrolidin-2-on-4-carboxylic acid, methyl ester.
Claim 5
Dependent Claim
11 words
The compound of claim 1, which is N-[3-[(2-benzoxazolyl)methoxy]phenyl]pyrrolidin-2-on-4-carboxylic acid, methyl ester.
References Cited (Backward Citations)
US4296120A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-11-18 | 1989-05-20 | 1989-11-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-11-18 | 1993-05-20 | 1993-11-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-11-18 | 1997-05-20 | 1997-11-19 | $7700.00 | Window Closed / Lapsed |