US4552879A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Benzoheterocyclic compounds and pharmaceutical composition thereof
Assignee: Otsuka Pharmaceutical Co Ltd
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Filing: 1983-05-25
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Granted: 1985-11-12
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Expires: 2003-05-25
Abstract
Abstract A benzoheterocyclic compound of the formula (I) ##STR1## wherein R 1 , R 2 , R 3 and n are as defined, and its pharmaceutically acceptable salts, processes for preparing same and antibacterial composition containing the benzoheterocyclic compound as an active ingredient and a pharmaceutically acceptable carrier are disclosed.
Inventors
- 👤 Hiroshi Ishikawa
- 👤 Testuyuki Uno
- 👤 Masanobu Kano
- 👤 Kazuyuki Nakagawa
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 01:52
CPC Classifications
C; C07; C07D; C07D209/00; C07D209/02; C07D209/44; C07D209/48; A; A61; A61P; A61P31/00; A61P31/04; C07D209/04; C07D209/08; C07D209/30; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/40; C07D211/44; C07D211/46; C07D215/00; C07D215/02; C07D215/16; C07D215/18; C07D215/38; C07D295/00; C07D295/22; C07D295/24; C07D455/00; C07D455/03; C07D455/04; C07D471/00; C07D471/02; C07D471/06
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
82 words
A benzoheterocyclic compound of the formula (I) ##STR15## wherein R 1 represents a hydrogen atom or a lower alkyl group; R 2 represents a hydrogen atom or a halogen atom; R 3 represents a 1-piperazinyl group substituted with an oxo group or a lower haloalkyl group, and n is an integer of 1 or 2; with the proviso that when n is 2, R 3 should not be a 1-piperazinyl group substituted with a lower haloalkyl group; or its pharmaceutically acceptable salt.
Claim 2
Dependent Claim
82 words
A benzoheterocyclic compound of the formula (I) ##STR15## wherein R 1 represents a hydrogen atom or a lower alkyl group; R 2 represents a hydrogen atom or a halogen atom; R 3 represents a 1-piperazinyl group substituted with an oxo group or a lower haloalkyl group, and n is an integer of 1 or 2; with the proviso that when n is 2, R 3 should not be a 1-piperazinyl group substituted with a lower haloalkyl group; or its pharmaceutically acceptable salt.
Claim 3
Dependent Claim
11 words
A compound as claimed in claim 1, wherein n is 2.
Claim 4
Dependent Claim
11 words
A compound as claimed in claim 1, wherein n is 1.
Claim 5
Dependent Claim
14 words
A compound as claimed in claim 2, wherein R 2 represents a halogen atom.
Claim 6
Dependent Claim
14 words
A compound as claimed in claim 2, wherein R 2 represents a hydrogen atom.
Claim 7
Dependent Claim
27 words
A compound as claimed in claim 4, wherein R 2 represents a fluorine atom and the position at which the fluorine atom is attached is the 9-position.
Claim 8
Dependent Claim
27 words
A compound as claimed in claim 4, wherein R 2 represents a chlorine atom and the position at which the chlorine atom is attached is the 9-position.
Claim 9
Dependent Claim
15 words
A compound as claimed in claim 6, wherein R 1 represents a lower alkyl group.
Claim 10
Dependent Claim
14 words
A compound as claimed in claim 8, wherein R 1 represents a methyl group.
Claim 11
Dependent Claim
14 words
A compound as claimed in claim 7, wherein R 1 represents a methyl group.
Claim 12
Dependent Claim
25 words
A compound as claimed in claim 4, wherein R 2 represents a fluorine atom attached to the 9-position and R 1 represents a methyl group.
Claim 13
Dependent Claim
40 words
A compound as claimed in claim 2, wherein R 1 represents a methyl group, R 2 represents a fluorine atom attached to the 9-position and the position at which the group represented by R 3 is attached is the 8-position.
Claim 14
Dependent Claim
19 words
A compound as claimed in claim 3, wherein the position at which R 3 is attached is the 9-position.
Claim 15
Dependent Claim
25 words
A compound as claimed in claim 13, wherein R 1 represents a methyl group and R 2 represents a fluorine atom attached to the 8-position.
Claim 16
Dependent Claim
25 words
A compound as claimed in claim 13, wherein R 1 represents a methyl group and R 2 represents a chlorine atom attached to the 8-position.
Claim 17
Dependent Claim
100 words
An antibacterial composition comprising an antibacterially effective amount of a benzoheterocyclic compound of the formula (I) ##STR16## wherein R 1 represents a hydrogen atom or a lower alkyl group; R 2 represents a hydrogen atom or a halogen atom; R 3 represents a 1-piperazinyl group substituted with an oxo group or a lower haloalkyl group, and n is an integer of 1 or 2; with the proviso that when n is 2, R 3 should not be a 1-piperazinyl group substituted with a lower haloalkyl group; or its pharmaceutically acceptable salt, as an active ingredient and a pharmaceutically, acceptable carrier.
Claim 18
Dependent Claim
100 words
An antibacterial composition comprising an antibacterially effective amount of a benzoheterocyclic compound of the formula (I) ##STR16## wherein R 1 represents a hydrogen atom or a lower alkyl group; R 2 represents a hydrogen atom or a halogen atom; R 3 represents a 1-piperazinyl group substituted with an oxo group or a lower haloalkyl group, and n is an integer of 1 or 2; with the proviso that when n is 2, R 3 should not be a 1-piperazinyl group substituted with a lower haloalkyl group; or its pharmaceutically acceptable salt, as an active ingredient and a pharmaceutically, acceptable carrier.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-11-11 | 1989-05-13 | 1989-11-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-11-11 | 1993-05-13 | 1993-11-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-11-11 | 1997-05-13 | 1997-11-12 | $7700.00 | Window Closed / Lapsed |