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US4551490A Expired / Lapsed US ⏱️ 0.0 years remaining

Adhesive composition resistant to biological fluids

Assignee: ER Squibb and Sons LLC
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Filing: 1983-12-30
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Granted: 1985-11-05
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Expires: 2003-12-30
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Abstract

Abstract Medical grade pressure sensitive adhesive compositions comprising a homogeneous mixture of one or more polyisobutylenes or blends of one or more polyisobutylenes and butyl rubber, one or more styrene radial or block type copolymers, mineral oil, one or more water soluble hydrocolloid gums, and a tackifier. One or more water swellable cohesive strengthening agents, an antioxidant, and various other optional ingredients may be included within the adhesive composition.

Inventors

  • 👤 Arthur Doyle
  • 👤 Frank M. Freeman

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 19:53
CPC Classifications
C; C07; C07D; C07D501/00; A; A61; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/58; A61L15/585; A61L24/00; A61L24/04; A61L24/043; C07D519/00; A61L2400/00; A61L2400/14; Y; Y10; Y10T; Y10T428/00; Y10T428/28; Y10T428/2852; Y10T428/2865; Y10T428/2878; Y10T428/2883

Claims Analysis

Total Claims: 30
Claim 1
Independent Claim 147 words
A pressure sensitive adhesive composition suitable for medical purposes consisting essentially of a substantially homogeneous mixture on a percent weight basis of from about 5% to about 30% by weight of one or more polyisobutylenes or a blend of one or more polyisobutylenes and butyl rubber, from about 3.0% to about 20% by weight of one or more styrene radial or block type copolymers, from about 8.0% to about 40% by weight of mineral oil, from about 15% to about 65% by weight of one or more water soluble hydrocolloid gums, up to about 15% by weight of one or more water swellable cohesive strengthening agents provided that said water soluble hydrocolloid gums and said water swellable cohesive strengthening agents together are present at from about 15% to about 65% by weight of said composition, and from about 7.5% to about 15% by weight of a tackifier.
Claim 2
Dependent Claim 147 words
A pressure sensitive adhesive composition suitable for medical purposes consisting essentially of a substantially homogeneous mixture on a percent weight basis of from about 5% to about 30% by weight of one or more polyisobutylenes or a blend of one or more polyisobutylenes and butyl rubber, from about 3.0% to about 20% by weight of one or more styrene radial or block type copolymers, from about 8.0% to about 40% by weight of mineral oil, from about 15% to about 65% by weight of one or more water soluble hydrocolloid gums, up to about 15% by weight of one or more water swellable cohesive strengthening agents provided that said water soluble hydrocolloid gums and said water swellable cohesive strengthening agents together are present at from about 15% to about 65% by weight of said composition, and from about 7.5% to about 15% by weight of a tackifier.
Claim 3
Dependent Claim 55 words
An adhesive composition of claim 1 wherein said water soluble hydrocolloid is selected from the group consisting of sodium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, gum karaya, and mixtures thereof and said water swellable cohesive strengthening agent is selected from the group consisting of cross-linked sodium carboxymethylcellulose, starch-acrylonitrile graft copolymers, and cross-linked dextran.
Claim 4
Dependent Claim 18 words
An adhesive composition of claim 2 wherein said styrene copolymer is a styrene-isoprene-styrene or a styrene-butadiene-styrene block polymer.
Claim 5
Dependent Claim 15 words
An adhesive composition of claim 3 wherein said styrene copolymer is a styrene-isoprene-styrene block copolymer.
Claim 6
Dependent Claim 17 words
An adhesive composition of claim 4 wherein said polyisobutylenes are one or more low molecular weight polyisobutylenes.
Claim 7
Dependent Claim 207 words
A pressure sensitive adhesive composition particularly suited for use in attaching a male incontinence device to a patient consisting essentially of a substantially homogeneous mixture on a percent weight basis of from about 5% to about 15% by weight of one or more low molecular weight polyisobutylenes or a blend of one or more low molecular weight polyisobutylenes and butyl rubber, from about 10% to about 20% by weight of a styrene block type copolymer selected from the group consisting of styrene-isoprene-styrene and styrene-butadiene-styrene block copolymers, from about 20% to about 40% by weight of mineral oil, from about 25% to about 65% by weight of a water soluble hydrocolloid selected from the group consisting of sodium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, gum karaya, and mixtures thereof, up to about 15% by weight of a water swellable cohesive strengthening agent selected from the group consisting of cross-linked sodium carboxymethylcellulose, starch-acrylonitrile graft copolymer, and cross-linked dextran provided that said water soluble hydrocolloids and said water swellable cohesive strengthening agents are together present at from about 25% to about 65% by weight of said composition, from about 7.5% to about 15% by weight of a tackifier, and up to about 0.5% by weight of an antioxidant.
Claim 8
Dependent Claim 207 words
A pressure sensitive adhesive composition particularly suited for use in attaching a male incontinence device to a patient consisting essentially of a substantially homogeneous mixture on a percent weight basis of from about 5% to about 15% by weight of one or more low molecular weight polyisobutylenes or a blend of one or more low molecular weight polyisobutylenes and butyl rubber, from about 10% to about 20% by weight of a styrene block type copolymer selected from the group consisting of styrene-isoprene-styrene and styrene-butadiene-styrene block copolymers, from about 20% to about 40% by weight of mineral oil, from about 25% to about 65% by weight of a water soluble hydrocolloid selected from the group consisting of sodium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, gum karaya, and mixtures thereof, up to about 15% by weight of a water swellable cohesive strengthening agent selected from the group consisting of cross-linked sodium carboxymethylcellulose, starch-acrylonitrile graft copolymer, and cross-linked dextran provided that said water soluble hydrocolloids and said water swellable cohesive strengthening agents are together present at from about 25% to about 65% by weight of said composition, from about 7.5% to about 15% by weight of a tackifier, and up to about 0.5% by weight of an antioxidant.
Claim 9
Dependent Claim 15 words
An adhesive composition of claim 6 wherein said styrene copolymer is a stryene-isoprene-styrene block copolymer.
Claim 10
Dependent Claim 34 words
An adhesive composition of claim 7 wherein said water soluble hydrocolloid and said water swellable cohesive strengthening agent together are present at from about 25% to about 50% by weight of said adhesive composition.
Claim 11
Dependent Claim 25 words
An adhesive composition of claim 8 wherein said water soluble hydrocolloid is sodium carboxymethylcellulose and said water swellable cohesive strengthening agent is cross-linked sodium carboxymethylcellulose.
Claim 12
Dependent Claim 15 words
An adhesive composition of claim 6 wherein said tackifier is a pentaerythritol ester of rosin.
Claim 13
Dependent Claim 12 words
An adhesive composition of claim 6 wherein said antioxidant is zinc dibutyldithiocarbamate.
Claim 14
Dependent Claim 202 words
A pressure sensitive adhesive composition particularly suited for use as an ostomy skin barrier consisting essentially of a substantially homogeneous mixture on a percent weight basis of from about 20% to about 30% by weight of one or more low molecular weight polyisobutylenes or a blend of one or more low molecular weight polyisobutylenes and butyl rubber, from about 3% to about 10% by weight of a styrene block type copolymer selected from the group consisting of styrene-isoprene-styrene and styrene-butadiene-styrene block copolymers, from about 9% to about 25% by weight of mineral oil, from about 30% to about 65% by weight of a water soluble hydrocolloid selected from the group consisting of sodium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, gum karaya, and mixtures thereof, up to about 15% by weight of a water swellable cohesive strengthening agent selected from the group consisting of cross-linked sodium carboxymethylcellulose, starch-acrylonitrile graft copolymer, and cross-linked dextran provided that said water soluble hydrocolloids and said water swellable cohesive strengthening agents are together present at from 30% to about 65% by weight of said composition, from about 7.5% to about 15% by weight of a tackifier, and up to about 0.5% by weight of an antioxidant.
Claim 15
Dependent Claim 202 words
A pressure sensitive adhesive composition particularly suited for use as an ostomy skin barrier consisting essentially of a substantially homogeneous mixture on a percent weight basis of from about 20% to about 30% by weight of one or more low molecular weight polyisobutylenes or a blend of one or more low molecular weight polyisobutylenes and butyl rubber, from about 3% to about 10% by weight of a styrene block type copolymer selected from the group consisting of styrene-isoprene-styrene and styrene-butadiene-styrene block copolymers, from about 9% to about 25% by weight of mineral oil, from about 30% to about 65% by weight of a water soluble hydrocolloid selected from the group consisting of sodium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, gum karaya, and mixtures thereof, up to about 15% by weight of a water swellable cohesive strengthening agent selected from the group consisting of cross-linked sodium carboxymethylcellulose, starch-acrylonitrile graft copolymer, and cross-linked dextran provided that said water soluble hydrocolloids and said water swellable cohesive strengthening agents are together present at from 30% to about 65% by weight of said composition, from about 7.5% to about 15% by weight of a tackifier, and up to about 0.5% by weight of an antioxidant.
Claim 16
Dependent Claim 15 words
An adhesive composition of claim 12 wherein said styrene copolymer is a styrene-isoprene-styrene block polymer.
Claim 17
Dependent Claim 34 words
An adhesive composition of claim 13 wherein said water soluble hydrocolloid and said water swellable cohesive strengthening agent together are present at from about 35% to about 55% by weight of said adhesive composition.
Claim 18
Dependent Claim 24 words
An adhesive composition of claim 14 wherein said water soluble hydrocolloid is a mixture of more than one of pectin, gelatin, and sodium carboxymethylcellulose.
Claim 19
Dependent Claim 15 words
An adhesive composition of claim 12 wherein said tackifier is a pentaerythritol ester of rosin.
Claim 20
Dependent Claim 12 words
An adhesive composition of claim 12 wherein said antioxidant is zinc dibutyldithiocarbamate.
Claim 21
Dependent Claim 201 words
A pressure sensitive adhesive composition particularly suited for use in a wound or burn dressing consisting essentially of a substantially homogeneous mixture on a percent weight basis of from about 5% to about 15% by weight of one or more low molecular weight polyisobutylenes or a blend of one or more low molecular weight polyisobutylenes and butyl rubber, from about 10% to about 20% by weight of a styrene block copolymer selected from the group consisting of styrene-isoprene-styrene and styrene-butadiene-styrene block copolymers, from about 20% to about 40% by weight of mineral oil, from about 30% to about 60% by weight of a water soluble hydrocolloid selected from the group consisting of sodium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, gum karaya, and mixture thereof, up to about 15% by weight of a water swellable cohesive strengthening agent selected from the group consisting of cross-linked sodium carboxymethylcellulose, starch-acrylonitrile graft copolymer, and cross-linked dextran provided that said water soluble hydrocolloids and said water swellable cohesive strengthening agents are together present at from about 30% to about 65% by weight of said composition, from about 7.5% to about 10% by weight of a tackifier, and up to about 0.5% of an antioxidant.
Claim 22
Dependent Claim 201 words
A pressure sensitive adhesive composition particularly suited for use in a wound or burn dressing consisting essentially of a substantially homogeneous mixture on a percent weight basis of from about 5% to about 15% by weight of one or more low molecular weight polyisobutylenes or a blend of one or more low molecular weight polyisobutylenes and butyl rubber, from about 10% to about 20% by weight of a styrene block copolymer selected from the group consisting of styrene-isoprene-styrene and styrene-butadiene-styrene block copolymers, from about 20% to about 40% by weight of mineral oil, from about 30% to about 60% by weight of a water soluble hydrocolloid selected from the group consisting of sodium carboxymethylcellulose, pectin, gelatin, guar gum, locust bean gum, gum karaya, and mixture thereof, up to about 15% by weight of a water swellable cohesive strengthening agent selected from the group consisting of cross-linked sodium carboxymethylcellulose, starch-acrylonitrile graft copolymer, and cross-linked dextran provided that said water soluble hydrocolloids and said water swellable cohesive strengthening agents are together present at from about 30% to about 65% by weight of said composition, from about 7.5% to about 10% by weight of a tackifier, and up to about 0.5% of an antioxidant.
Claim 23
Dependent Claim 15 words
An adhesive composition of claim 18 wherein said styrene copolymer is a styrene-isoprene-styrene block copolymer.
Claim 24
Dependent Claim 15 words
An adhesive composition of claim 18 wherein said tackifier is a pentaerythritol ester of rosin.
Claim 25
Dependent Claim 12 words
An adhesive composition of claim 18 wherein said antioxidant is zinc dibutyldithiocarbamate.
Claim 26
Dependent Claim 149 words
A pressure sensitive adhesive composition particularly suited for use as an ostomy skin barrier consisting essentially of a substantially homogeneous mixture on a percent weight basis of from about 5% to about 30% by weight of a blend of one or more low molecular weight polyisobutylenes and butyl rubber, said polyisobutylenes and butyl rubber blended together on a weight basis of from about 4 parts polyisobutylene to about 1 part butyl rubber to about 1 part polyisobutylene to about 4 parts butyl rubber, from about 3% to about 10% by weight of a styrene-isoprene-styrene block copolymer, from about 9% to about 25% by weight of mineral oil, from about 35% to about 55% by weight of a mixture of more than one of pectin, gelatin, and sodium carboxymethylcellulose, from about 7.5% to about 15% by weight of a tackifier, and up to about 0.5% by weight of an antioxidant.
Claim 27
Dependent Claim 149 words
A pressure sensitive adhesive composition particularly suited for use as an ostomy skin barrier consisting essentially of a substantially homogeneous mixture on a percent weight basis of from about 5% to about 30% by weight of a blend of one or more low molecular weight polyisobutylenes and butyl rubber, said polyisobutylenes and butyl rubber blended together on a weight basis of from about 4 parts polyisobutylene to about 1 part butyl rubber to about 1 part polyisobutylene to about 4 parts butyl rubber, from about 3% to about 10% by weight of a styrene-isoprene-styrene block copolymer, from about 9% to about 25% by weight of mineral oil, from about 35% to about 55% by weight of a mixture of more than one of pectin, gelatin, and sodium carboxymethylcellulose, from about 7.5% to about 15% by weight of a tackifier, and up to about 0.5% by weight of an antioxidant.
Claim 28
Dependent Claim 37 words
An adhesive composition of claim 22 wherein said low molecular weight polyisobutylene and said butyl rubber are blended on a weight basis of from about 1 part low molecular weight polyisobutylene to about 2 parts butyl rubber.
Claim 29
Dependent Claim 15 words
An adhesive composition of claim 23 wherein said tackifier is a pentaerythritol ester of rosin.
Claim 30
Dependent Claim 12 words
An adhesive composition of claim 23 wherein said antioxidant is zinc dibutyldithiocarbamate.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-11-04 1989-05-06 1989-11-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-11-04 1993-05-06 1993-11-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-11-04 1997-05-06 1997-11-05 $7700.00 Window Closed / Lapsed

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