US4540408A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Applicators for pharmacologically active agents, their preparation and use
Assignee: Chauvin Pharmaceuticals Ltd
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Filing: 1982-04-29
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Granted: 1985-09-10
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Expires: 2002-04-29
Abstract
Abstract A disposable applicator for placing a pharmacologically active agent in contact with a moist body surface, especially the eye is in the form of an elongate strip disposed at one end of which is a soluble matrix element containing the pharmacologically active agent so that on contact with the moist body surface the matrix element separates from the remainder of the strip. In a preferred form the matrix element is attached to the remainder of the strip by a thin water soluble membrane which rapidly dissolves in body fluid thereby releasing the matrix element to the body surface. Processes for the preparation of the disposable applicators are also described.
Inventors
- 👤 Ronald Lloyd
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 23:21
CPC Classifications
A; A61; A61F; A61F9/00; A61F9/0008; A61M; A61M35/00; A61M35/003
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
88 words
A disposable applicator for placing a pharmacologically active agent in contact with a moist body surface which applicator is in the form of an elongate strip with a pharmacologically active agent disposed at one end thereof said pharmacologically active agent being in a soluble matrix element which is attached to the rest of the strip by a rapidly soluble water activated membrane along which the soluble matrix element will separate from the remainder of the strip when the soluble matrix element is applied to a moist body surface.
Claim 2
Dependent Claim
88 words
A disposable applicator for placing a pharmacologically active agent in contact with a moist body surface which applicator is in the form of an elongate strip with a pharmacologically active agent disposed at one end thereof said pharmacologically active agent being in a soluble matrix element which is attached to the rest of the strip by a rapidly soluble water activated membrane along which the soluble matrix element will separate from the remainder of the strip when the soluble matrix element is applied to a moist body surface.
Claim 3
Dependent Claim
85 words
A disposable applicator for placing an ophthalmic agent into the eye which applicator is in the form of an elongate strip with an ophthalmic agent disposed at one end thereof said ophthalmic agent being in a water soluble matrix element which is attached to the rest of the strip by a rapidly soluble water activated membrane line along which the soluble matrix element will separate from the remainder of the strip when the soluble matrix element is applied to the moist surface of the eye.
Claim 4
Dependent Claim
85 words
A disposable applicator for placing an ophthalmic agent into the eye which applicator is in the form of an elongate strip with an ophthalmic agent disposed at one end thereof said ophthalmic agent being in a water soluble matrix element which is attached to the rest of the strip by a rapidly soluble water activated membrane line along which the soluble matrix element will separate from the remainder of the strip when the soluble matrix element is applied to the moist surface of the eye.
Claim 5
Dependent Claim
28 words
A disposable applicator according to claim 2 in which the soluble matrix element is in the form of a soluble film portion comprising a non-toxic water soluble polymer.
Claim 6
Dependent Claim
17 words
A disposable applicator according to claim 3 in which the non-toxic water soluble polymer is polyvinyl alcohol.
Claim 7
Dependent Claim
19 words
A disposable applicator according to claim 3, in which the soluble film portion is rectangular, including square, in shape.
Claim 8
Dependent Claim
44 words
A disposable applicator according to claim 3 in which the soluble film portion is in the shape of a rectangle or square having dimensions of from 3 to 20 mm long, from 2 to 7.5 mm wide and from 12.5 to 125 microns thick.
Claim 9
Dependent Claim
21 words
A disposable applicator according to claim 3 in which the soluble film portion has a pattern of thicker and thinner areas.
Claim 10
Dependent Claim
27 words
A disposable applicator according to claim 2 in which the weight of ophthalmic agent present in the soluble matrix element is between 1 microgramme to 2.5 milligrams.
Claim 11
Dependent Claim
61 words
A disposable applicator according to claim 2 in which the elongate strip has a handle portion, an intermediate flexible portion and a soluble matrix element containing an ophthalmic agent which soluble matrix element is attached to the intermediate flexible portion by a membrane of thickness less than 15 microns which dissolves rapidly in contact with the moist surface of the eye.
References Cited (Backward Citations)
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Cited
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Cited
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-09-09 | 1989-03-11 | 1989-09-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-09-09 | 1993-03-11 | 1993-09-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-09-09 | 1997-03-11 | 1997-09-10 | $7700.00 | Window Closed / Lapsed |