US4533348A
Expired / Lapsed
US
⏱️ 0.0 years remaining
In-line drug dispenser for use in intravenous therapy
Assignee: Alza Corp
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Filing: 1984-09-12
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Granted: 1985-08-06
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Expires: 2004-09-12
Abstract
Abstract A formulation dispenser is disclosed for use in a parenteral delivery system. The dispenser comprises an inlet for admitting fluid into the dispenser and an outlet for letting fluid leave the dispenser. A beneficial agent is housed in a formulation chamber in the dispenser and a membrane permeable to fluid and agent defines one boundary of the formulation chamber. A piston is slideably disposed in the dispenser for governing the flow of fluid through the dispenser, or for permitting fluid to contact the membrane and enter the formulation chamber for forming a solution containing agent that flows through the outlet into the parenteral system.
Inventors
- 👤 Allan M. Wolfe
- 👤 James M. Davenport
- 👤 Felix Theeuwes
- 👤 Su I. Yum
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:29
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/1407; A61M5/1409; Y; Y10; Y10T; Y10T137/00; Y10T137/4891
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
175 words
An intravenous system for delivering a drug formulation, wherein the intravenous system comprises: (a) a reservoir of an intravenously acceptable fluid; (b) a formulation dispenser in fluid communication with the reservoir, the formulation dispenser comprising: (1) a housing surrounding an internal lumen, the housing having openings at its opposite ends; (2) piston means disposed in one opening of the housing; (3) a beneficial drug in the housing present in an effective amount for producing a therapeutic effect, said drug a member selected from the group consisting of solid, crystalline, granule, power, tablet, dried and lyophilized pharmaceutically acceptable forms that produce an intravenously administrable drug formulation when contacted by fluid that enters the dispenser; (4) a fluid permeable membrane in the housing positioned between the drug and the piston; (5) a closure disposed at the other opening of the housing facing the drug; (6) inlet means in the housing for letting fluid enter the housing and contact the beneficial drug; and, (7) outlet means in the housing for letting intravenously administrable drug formulation leave the housing.
Claim 2
Dependent Claim
175 words
An intravenous system for delivering a drug formulation, wherein the intravenous system comprises: (a) a reservoir of an intravenously acceptable fluid; (b) a formulation dispenser in fluid communication with the reservoir, the formulation dispenser comprising: (1) a housing surrounding an internal lumen, the housing having openings at its opposite ends; (2) piston means disposed in one opening of the housing; (3) a beneficial drug in the housing present in an effective amount for producing a therapeutic effect, said drug a member selected from the group consisting of solid, crystalline, granule, power, tablet, dried and lyophilized pharmaceutically acceptable forms that produce an intravenously administrable drug formulation when contacted by fluid that enters the dispenser; (4) a fluid permeable membrane in the housing positioned between the drug and the piston; (5) a closure disposed at the other opening of the housing facing the drug; (6) inlet means in the housing for letting fluid enter the housing and contact the beneficial drug; and, (7) outlet means in the housing for letting intravenously administrable drug formulation leave the housing.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-08-05 | 1989-02-04 | 1989-08-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-08-05 | 1993-02-04 | 1993-08-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-08-05 | 1997-02-04 | 1997-08-06 | $7700.00 | Window Closed / Lapsed |