US4532937A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sebum collection and monitoring means and method
Assignee: CUDERM Corp A NJ CORP
•
Filing: 1983-11-28
•
Granted: 1985-08-06
•
Expires: 2003-11-28
Abstract
Abstract Means for absorbing sebum screted by sebacious glands of a subject as well as providing semi-quantitative estimation of the rate of sebum production at various sites on the subject's skin and a record of excretion patterns on the skin, said means comprising a microporous hydrophobic polymeric film substrate coated on a major surface with a high molecular weight adhesive that is resistant to migration into the pores of the polymeric film. Said means may also be used to provide therapy by absorbing excess sebum or delivering medication to sites or abnormal sebum secretion. Method for ascertaining secretion patterns on the skin by applying to the skin for a preselected time a microporous, hydrophobic, polymeric film.
Inventors
- 👤 David L. Miller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 13:43
CPC Classifications
A; A61; A61B; A61B10/00; A61B10/0035; A61B10/0045; A61B10/0064; A61K; A61K9/00; A61K9/70
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
192 words
A device for collecting sebum as it is secreted from the sebaceous glands of a subject which comprises (a) an open-celled, microporous, hydrophobic polymeric film having coated on a major surface thereof (b) a layer of synthetic, pressure-sensitive adhesive consisting essentially of high molecular weight components that are resistant to migration into the pores of said microporous film, said layer of adhesive being sufficiently thick and continous to hold said microporous film in close proximity with the openings of said sebaceous glands, yet sufficiently thin to permit passage therethrough, and into said pores of said microporous film, of substantially all of the sebum secreted by said glands during a period of contact between said device and said sebaceous glands, said microporous film having a pore volume of from about 25% to about 50%, a film thickness of from about 0.01 mm to about 0.05 mm, the pores of said film having a mean effective diameter of less than about 0.1 micron, and said film being opaque to light or opolescent when its pores are filled with gaseous material but substantially translucent when said pores are filled with sebum or another hydrophobic substance.
Claim 2
Independent Claim
192 words
A device for collecting sebum as it is secreted from the sebaceous glands of a subject which comprises (a) an open-celled, microporous, hydrophobic polymeric film having coated on a major surface thereof (b) a layer of synthetic, pressure-sensitive adhesive consisting essentially of high molecular weight components that are resistant to migration into the pores of said microporous film, said layer of adhesive being sufficiently thick and continous to hold said microporous film in close proximity with the openings of said sebaceous glands, yet sufficiently thin to permit passage therethrough, and into said pores of said microporous film, of substantially all of the sebum secreted by said glands during a period of contact between said device and said sebaceous glands, said microporous film having a pore volume of from about 25% to about 50%, a film thickness of from about 0.01 mm to about 0.05 mm, the pores of said film having a mean effective diameter of less than about 0.1 micron, and said film being opaque to light or opolescent when its pores are filled with gaseous material but substantially translucent when said pores are filled with sebum or another hydrophobic substance.
Claim 3
Dependent Claim
29 words
The device of claim 1 wherein said microporous film has a pore volume of about 40% and a film thickness of from about 0.01 mm to abut 0.03 mm.
Claim 4
Dependent Claim
11 words
The device of claim 1 wherein said film is microporous polypropylene.
Claim 5
Dependent Claim
25 words
The device of claim 1 wherein said film is a non-woven material comprising fibers selected from the group consisting of polyester, polyether and polyolefin fibers.
Claim 6
Dependent Claim
57 words
The device of claim 3 wherein said adhesive consists essentially of a high molecular weight polymer selected from the group consisting of the homopolymers and heteropolymers of monomers selected from the C 2 to C 10 aliphatic esters of acrylic and methacrylic acid, the C 2 to C 10 aliphatic vinyl ethers and esters, acrylamides and urethanes.
Claim 7
Dependent Claim
19 words
The device of claim 5 wherein said heteropolymer is a terpolymer of 2-ethylhexyl acrylate, vinyl acetate and tert.-butyl acrylamide.
Claim 8
Independent Claim
222 words
A method for determining the location and approximate rate of sebum secretion of sebaceous glands of a subject which comprises (a) applying to the skin of said subject for a predetermined time a device which comprises (i) an open-celled, microporous, hydrophobic polymeric film having coated on a major surface thereof (ii) a layer of synthetic, pressure-sensitive adhesive consisting essentially of high molecular weight components that are resistant to migration into the pores of said microporous film, said layer of adhesive being sufficiently thick and continuous to hold said microporous film in close proximity with the openings of said sebaceous glands, yet sufficiently thin to permit passage therethrough, and into said pores of said microporous film, of substantially all of the sebum secreted by said glands during a period of contact between said device and said sebaceous glands, said microporous film having a pore volume of from about 25% to about 50%, a film thickness of from about 0.01 mm to about 0.05 mm, the pores of said film having a mean effective diameter of less than about 0.1 micron, and said film being opaque to light or opalescent when its pores are filled with gaseous material but substantially translucent when said pores are filled with sebum or another hydrophobic substance, and (b) removing said device upon the expiration of said time period.
Claim 9
Independent Claim
222 words
A method for determining the location and approximate rate of sebum secretion of sebaceous glands of a subject which comprises (a) applying to the skin of said subject for a predetermined time a device which comprises (i) an open-celled, microporous, hydrophobic polymeric film having coated on a major surface thereof (ii) a layer of synthetic, pressure-sensitive adhesive consisting essentially of high molecular weight components that are resistant to migration into the pores of said microporous film, said layer of adhesive being sufficiently thick and continuous to hold said microporous film in close proximity with the openings of said sebaceous glands, yet sufficiently thin to permit passage therethrough, and into said pores of said microporous film, of substantially all of the sebum secreted by said glands during a period of contact between said device and said sebaceous glands, said microporous film having a pore volume of from about 25% to about 50%, a film thickness of from about 0.01 mm to about 0.05 mm, the pores of said film having a mean effective diameter of less than about 0.1 micron, and said film being opaque to light or opalescent when its pores are filled with gaseous material but substantially translucent when said pores are filled with sebum or another hydrophobic substance, and (b) removing said device upon the expiration of said time period.
Claim 10
Dependent Claim
21 words
The method of claim 7 which further comprises (c) observing the location, number and size of translucent areas on said device.
Claim 11
Dependent Claim
23 words
The method of claim 7 which further comprises comparing the number and size of translucent areas on said device with a preselected standard.
Claim 12
Dependent Claim
22 words
The method of claim 7 which further comprises recovering said sebum from said device and determining the amount of said recovered sebum.
Claim 13
Dependent Claim
22 words
The method of claim 7 which further comprises recovering said sebum from said device and determining the composition of said recovered sebum.
Claim 14
Dependent Claim
22 words
The method of claim 7 wherein said predetermined time is in the range of from about 20 minutes to about 3 hours.
Claim 15
Dependent Claim
22 words
The method of claim 12 wherein said predetermined time is in the range of from about 30 minutes to about 90 minutes.
Claim 16
Dependent Claim
14 words
The method of claim 12 wherein said time is at least about 30 minutes.
Claim 17
Independent Claim
200 words
A method for removing excess sebum from the skin of a subject which comprises periodically, sequentially applying thereto and thereafter removing therefrom a device which comprises (a) an open-celled, microporous, hydrophobic polymeric film having coated on a major surface thereof (b) a layer of synthetic, pressure-sensitive adhesive consisting essentially of high molecular weight components that are resistant to migration into the pores of said microporous film, said layer of adhesive being sufficiently thick and continous to hold said microporous film in close proximity with the openings of said sebaceous glands, yet sufficiently thin to permit passage therethrough, and into said pores of said microporous film, of substantially all of the sebum secreted by said glands during a period of contact between said device and said sebaceous glands, said microporous film having a pore volume of from about 25% to about 50%, a film thickness of from about 0.01 mm to about 0.05 mm, the pores of said film having a mean effective diameter of less than about 0.1 micron, and said film being opaque to light or opalescent when its pores are filled with gaseous material but substantially translucent when said pores are filled with sebum or another hydrophobic substance.
Claim 18
Independent Claim
200 words
A method for removing excess sebum from the skin of a subject which comprises periodically, sequentially applying thereto and thereafter removing therefrom a device which comprises (a) an open-celled, microporous, hydrophobic polymeric film having coated on a major surface thereof (b) a layer of synthetic, pressure-sensitive adhesive consisting essentially of high molecular weight components that are resistant to migration into the pores of said microporous film, said layer of adhesive being sufficiently thick and continous to hold said microporous film in close proximity with the openings of said sebaceous glands, yet sufficiently thin to permit passage therethrough, and into said pores of said microporous film, of substantially all of the sebum secreted by said glands during a period of contact between said device and said sebaceous glands, said microporous film having a pore volume of from about 25% to about 50%, a film thickness of from about 0.01 mm to about 0.05 mm, the pores of said film having a mean effective diameter of less than about 0.1 micron, and said film being opaque to light or opalescent when its pores are filled with gaseous material but substantially translucent when said pores are filled with sebum or another hydrophobic substance.
References Cited (Backward Citations)
US3426754A
Cited
US3731683A
Cited
US3906933A
Cited
US4073291A
Cited
US4190056A
Cited
US4190060A
Cited
US4224950A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-08-05 | 1989-02-04 | 1989-08-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-08-05 | 1993-02-04 | 1993-08-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-08-05 | 1997-02-04 | 1997-08-06 | $7700.00 | Window Closed / Lapsed |