US4523005A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Extrudable polyurethane for prosthetic devices prepared from a diisocyanate, a polytetramethylene ether polyol, and 1,4-butane diol
Assignee: Thermo Fisher Scientific Inc
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Filing: 1984-04-17
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Granted: 1985-06-11
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Expires: 2004-04-17
Abstract
Abstract Reaction product of an aliphatic organic diisocyanate, a high molecular weight polyether polyol (poly tetra methylene ether glycol) and 1,4 butane diol. The resulting polymers have thromboresistant properties, a long flexural life and are extrudable. The polyurethane polymer is ideal for forming transvenous cardiac pacemaker leads, blood bags, intravenous and intra-arterial catheters and tubing, and other shaped devices which must be formed of a blood compatible material.
Inventors
- 👤 Michael Szycher
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 15:32
CPC Classifications
C; C08; C08G; C08G18/00; C08G18/06; C08G18/28; C08G18/65; C08G18/66; C08G18/6666; C08G18/667; C08G18/6674; C08G18/40; C08G18/48; C08G18/4854; C08G18/6603; C08G18/6607; C08G18/70; C08G18/72; C08G18/73; C08G18/74; C08G18/75
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
128 words
A polymer for use in extruding and molding devices requiring a high degree of blood compatibility, said polymer consisting essentially of a polyurethane elastomer which is the reaction product of: (a) dicyclohexyl methane diisocyanate; (b) a polytetramethylene ether polyol having a molecular weight in the range of 1000-3000; and (c) 1,4 butane diol, wherein the number of moles of dicylohexyl methane diisocyanate molecules is equal to the sum of the number of moles of polytetramethylene ether polyol and the number of moles of 1,4 butane diol; the molar ratio of 1,4 butane diol to polytetramethylene ether glycol is between 1.1 to 0.9 and 1.5 to 0.5; and the average molecular weight of the polymer is 120,000-180,000 units, and a weight average molecular weight of 285,000-335,000 molecular weight units.
Claim 2
Dependent Claim
128 words
A polymer for use in extruding and molding devices requiring a high degree of blood compatibility, said polymer consisting essentially of a polyurethane elastomer which is the reaction product of: (a) dicyclohexyl methane diisocyanate; (b) a polytetramethylene ether polyol having a molecular weight in the range of 1000-3000; and (c) 1,4 butane diol, wherein the number of moles of dicylohexyl methane diisocyanate molecules is equal to the sum of the number of moles of polytetramethylene ether polyol and the number of moles of 1,4 butane diol; the molar ratio of 1,4 butane diol to polytetramethylene ether glycol is between 1.1 to 0.9 and 1.5 to 0.5; and the average molecular weight of the polymer is 120,000-180,000 units, and a weight average molecular weight of 285,000-335,000 molecular weight units.
Claim 3
Dependent Claim
21 words
The polymer of claim 1 wherein the molar ratio of 1,4 butane diol to polytetramethylene ether polyol is 1.3 to 0.7.
Claim 4
Dependent Claim
15 words
The polymer of claim 2 wherein the molecular weight of the polytetramethylene ether is 1000.
Claim 5
Dependent Claim
32 words
The polymer as set forth in claim 1 wherein the polymer has incorporated therein one or more of the following components: (1) a catalyst; (2) an anti-oxidant; and (3) an extrusion lubricant.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-06-10 | 1988-12-10 | 1989-06-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-06-10 | 1992-12-10 | 1993-06-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-06-10 | 1996-12-10 | 1997-06-11 | $7700.00 | Window Closed / Lapsed |