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US4520249A Expired / Lapsed US ⏱️ 0.0 years remaining

Method of and apparatus for selective localized differential hyperthermia of a medium

Assignee: SUBMICRON Inc A CORP OF
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Filing: 1982-09-16
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Granted: 1985-05-28
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Expires: 2002-09-16
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Abstract

Abstract Apparatus generates a pulsed, alternating magnetic field which is coupled to magnetizable particles of submicron size dispersed in colloidal suspension in a medium. The frequency of the applied magnetic field is related to the size of the particles in such a manner as to maximize dissipative heat coupling to the medium. The differential temperature rise in the area of the medium surrounding the particles may be controlled by the concentration of the particles. Thus, defined temperature rises may be selectively produced in highly localized areas.

Inventors

  • 👤 George H. Czerlinski

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 06:26
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/40; A61N1/403; H; H05; H05B; H05B6/00; H05B6/64

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 131 words
Apparatus for inducing a localized temperature rise in a medium comprising: means for generating an alternating magnetic field applied to at least a portion of said medium, said field having a predetermined frequency; a quantity of magnetizable particles dispersed in said portion of said medium at a known concentration, said particles being selected to have a Curie point approximately one-half the desired temperature rise above the ambient temperature of said medium, said portion of said medium being the region of desired temperature rise, said particles having a mean radius the square of which radius being inversely related to said frequency of said magnetic field, thereby to maximize the coupling of magnetocaloric heating of particles to the dissipative, irreversible heat loss from said particles to the neighboring local areas of said medium.
Claim 2
Dependent Claim 131 words
Apparatus for inducing a localized temperature rise in a medium comprising: means for generating an alternating magnetic field applied to at least a portion of said medium, said field having a predetermined frequency; a quantity of magnetizable particles dispersed in said portion of said medium at a known concentration, said particles being selected to have a Curie point approximately one-half the desired temperature rise above the ambient temperature of said medium, said portion of said medium being the region of desired temperature rise, said particles having a mean radius the square of which radius being inversely related to said frequency of said magnetic field, thereby to maximize the coupling of magnetocaloric heating of particles to the dissipative, irreversible heat loss from said particles to the neighboring local areas of said medium.
Claim 3
Dependent Claim 24 words
The apparatus of claim 1 wherein the differential temperature rise of said medium is related to the concentration of said particles in said medium.
Claim 4
Dependent Claim 19 words
The apparatus of claim 1 wherein the median radius of said particles is in the range of 0.05-1.0 microns.
Claim 5
Dependent Claim 16 words
The apparatus of claim 1 wherein said medium is heterogeneous and is at least partially fluid.
Claim 6
Dependent Claim 25 words
The apparatus of claim 4 wherein said magnetic field is characterized in having a high magnetic field strength and a relatively low electric field strength.

References Cited (Backward Citations)

US3718804A Cited
US4035547A Cited
US4003840A Cited
US4136683A Cited
US4190053A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-05-27 1988-11-26 1989-05-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-05-27 1992-11-26 1993-05-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-05-27 1996-11-26 1997-05-28 $7700.00 Window Closed / Lapsed

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