US4518589A
Expired / Lapsed
US
⏱️ 0.0 years remaining
BBM-2478 Antibiotic complex
Assignee: Bristol Myers Co
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Filing: 1983-10-03
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Granted: 1985-05-21
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Expires: 2003-10-03
Abstract
Abstract A novel antibiotic complex designated BBM-2478 is produced by fermentation of an actinomycete strain J907-21 (ATCC 39417). The complex may be separated chromatographically into two bioactive components designated BBM-2478A and BBM-2478B. The BBM-2478A component displays both antibacterial and antitumor activity while the BBM-2478B component has antibacterial activity.
Inventors
- 👤 Masataka Konishi
- 👤 Koko Sugawara
- 👤 Takeo Miyaki
- 👤 Hiroshi Kawaguchi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 10:27
CPC Classifications
C; C07; C07H; C07H17/00; C07H17/04; A; A61; A61P; A61P31/00; A61P31/04; A61P35/00; C12; C12N; C12N1/00; C12N1/20; C12N1/205; C12P; C12P19/00; C12P19/44; C12P19/60; C12R; C12R2001/00; C12R2001/01; C12R2001/465
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
7 words
The antibiotic BBM-2478A having the formula ##STR9##
Claim 2
Dependent Claim
7 words
The antibiotic BBM-2478A having the formula ##STR9##
Claim 3
Dependent Claim
7 words
The antibiotic BBM-2478B having the formula ##STR10##
Claim 4
Dependent Claim
7 words
The antibiotic BBM-2478B having the formula ##STR10##
Claim 5
Dependent Claim
30 words
A method for therapeutically treating an animal host affected by a bacterial infection which comprises administering to said host an effective antibacterial dose of BBM-2478A as defined in claim 1.
Claim 6
Dependent Claim
30 words
A method for therapeutically treating an animal host affected by a bacterial infection which comprises administering to said host an effective antibacterial dose of BBM-2478B as defined in claim 2.
Claim 7
Dependent Claim
39 words
A method for therapeutically treating a mammalian host affected by a malignant tumor selected from P388 leukemia, L1210 leukemia or B16 melanoma which comprises administering to said host an effective tumor-inhibiting dose of BBM-2478A as defined in claim 1.
Claim 8
Dependent Claim
23 words
A pharmaceutical composition comprising an effective antibacterial amount of BBM-2478A as defined in claim 1 in combination with a pharmaceutical carrier or diluent.
Claim 9
Dependent Claim
23 words
A pharmaceutical composition comprising an effective antibacterial amount of BBM-2478B as defined in claim 2 in combination with a pharmaceutical carrier or diluent.
Claim 10
Dependent Claim
43 words
A pharmaceutical composition for treatment of a mammalian host affected by a malignant tumor selected from P388 leukemia, L1210 leukemia or B16 melanoma comprising an effective tumor-inhibiting amount of BBM-2478A as defined in claim 1 in combination with a pharmaceutical carrier or diluent.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-05-20 | 1988-11-19 | 1989-05-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-05-20 | 1992-11-19 | 1993-05-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-05-20 | 1996-11-19 | 1997-05-21 | $7700.00 | Window Closed / Lapsed |