US4516276A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bone substitute and a method of production thereof
Assignee: Oscobal AG
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Filing: 1984-03-26
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Granted: 1985-05-14
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Expires: 2004-03-26
Abstract
Abstract A bone substitute comprised of collagen material in the form of fleece or a spatial meshwork having apatite, the mineral component of bone material, admixed therewith. The structure of the collagen material may be strengthened by carbohydrate or starch or may be applied, in the form of a coating, to a honeycomb-like basic structure made from a variety of materials. Such a bone substitute has a good support quality, promotes bone growth and also has a good styptic or haemostatic effect.
Inventors
- 👤 Heinz Mittelmeier
- 👤 Heinz Moser
- 👤 Beat Leu
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 04:18
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/54; A61L27/14; A61L27/26; A61L27/40; A61L27/44; A61L27/46; A61L2300/00; A61L2300/40; A61L2300/404; A61L2300/406; A61L2430/00; A61L2430/02
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
38 words
A bone substitute consisting essentially of a mixture of collagen fleece with apatite in the form of powder or granules, wherein the collagen is present in the form of an enzymatically treated, cleansed, lyophilized and sterilized collagen fleece.
Claim 2
Dependent Claim
38 words
A bone substitute consisting essentially of a mixture of collagen fleece with apatite in the form of powder or granules, wherein the collagen is present in the form of an enzymatically treated, cleansed, lyophilized and sterilized collagen fleece.
Claim 3
Dependent Claim
18 words
A bone substitute according to claim 1, additionally containing fibrin as a strengthening agent for said collagen fleece.
Claim 4
Dependent Claim
19 words
A bone substitute according to claim 1, in the form of a coating applied to a honeycomb-like basic structure.
Claim 5
Dependent Claim
36 words
A bone substitute according to claim 3, wherein the honeycomb-like basic structure is made from a material selected from the group consisting of plastics materials, textiles, metals, ceramics, carbon fibre fabrics and carbon or bone cement.
Claim 6
Dependent Claim
13 words
A bone substitute according to claim 1 having the shape of natural bones.
Claim 7
Dependent Claim
10 words
A bone substitute according to claim 1 additionally containing antibiotics.
Claim 8
Independent Claim
78 words
A method of producing a bone substitute material, wherein said material consists essentially of a mixture of collagen fleece and apatite, and wherein said collagen fleece is present in the form of enzymatically treated, cleansed, lyophilized and sterilized collagen fleece, comprising the steps of forming a thin layer of collagen fleece, dusting said collagen fleece with apatite powder or granules, and subsequently pressing the apatite-dusted collagen fleece to cause the apatite to be pressed into said collagen fleece.
Claim 9
Independent Claim
78 words
A method of producing a bone substitute material, wherein said material consists essentially of a mixture of collagen fleece and apatite, and wherein said collagen fleece is present in the form of enzymatically treated, cleansed, lyophilized and sterilized collagen fleece, comprising the steps of forming a thin layer of collagen fleece, dusting said collagen fleece with apatite powder or granules, and subsequently pressing the apatite-dusted collagen fleece to cause the apatite to be pressed into said collagen fleece.
Claim 10
Independent Claim
65 words
A method of producing a bone substitute material, wherein said material consists essentially of a mixture of collagen fleece and apatite, and wherein said collagen fleece is present in the form of enzymatically treated, cleansed, lyophilized and sterilized collagen fleece, comprising the steps of mixing said collagen fleece with apatite powder or granules, forming said mixture into a predetermined configuration and drying said formed mixture.
Claim 11
Independent Claim
65 words
A method of producing a bone substitute material, wherein said material consists essentially of a mixture of collagen fleece and apatite, and wherein said collagen fleece is present in the form of enzymatically treated, cleansed, lyophilized and sterilized collagen fleece, comprising the steps of mixing said collagen fleece with apatite powder or granules, forming said mixture into a predetermined configuration and drying said formed mixture.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-05-13 | 1988-11-12 | 1989-05-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-05-13 | 1992-11-12 | 1993-05-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-05-13 | 1996-11-12 | 1997-05-14 | $7700.00 | Window Closed / Lapsed |