US4512992A
Expired / Lapsed
US
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Treatment with dialkoxy pyridopyrimidine compounds
Assignee: SmithKline Beecham Corp
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Filing: 1981-02-06
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Granted: 1985-04-23
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Expires: 2001-02-06
Abstract
Abstract This application is directed to treatment of psoriasis with a pyrido pyrimidine compound such as 2,4-diamino-6-(3,4-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine.
Inventors
- 👤 David S. Duch
- 👤 Charles A. Nichol
- 👤 Carl W. Sigel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 13:17
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/02; C07D471/04
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
49 words
A method of treating psoriasis in a mammal suffering from psoriasis comprising the administration of a non-toxic, effective antipsoriasis amount of a compound of formula (II): ##STR25## wherein R and R' are lower (C 1 -C 6 ) alkyl, or pharmaceutically acceptable acid addition salt thereof to said mammal.
Claim 2
Independent Claim
49 words
A method of treating psoriasis in a mammal suffering from psoriasis comprising the administration of a non-toxic, effective antipsoriasis amount of a compound of formula (II): ##STR25## wherein R and R' are lower (C 1 -C 6 ) alkyl, or pharmaceutically acceptable acid addition salt thereof to said mammal.
Claim 3
Dependent Claim
12 words
A method according to claim 1 in which said compound is 2,4-diamino-6-(3,4-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine.
Claim 4
Dependent Claim
20 words
The method of claim 1 or 2 in which the compound or salt is administered in a pharmaceutically acceptable carrier.
Claim 5
Dependent Claim
22 words
The method of claim 1 or 2 in which the compound or salt is administered as a part of a topical formulation.
Claim 6
Dependent Claim
37 words
The method of claim 1 or 2 in which the compound or salt is administered as a part of a topical formulation in which the compound or salt is at a concentration of 0.05 to 2% w/w.
Claim 7
Dependent Claim
24 words
The method of claim 1 or 2 in which the compound or salt is administered as part of an oral preparation or parenteral preparation.
Claim 8
Dependent Claim
30 words
The method of claim 1 or 2 in which the compound or salt is administered in a pharmaceutically acceptable carrier in a form suitable for topical, parenteral or oral administration.
Claim 9
Dependent Claim
20 words
The method of claim 7 in which the amount of the compound or salt is 50 mg to 1 gram.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-04-22 | 1988-10-22 | 1989-04-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-04-22 | 1992-10-22 | 1993-04-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-04-22 | 1996-10-22 | 1997-04-23 | $7700.00 | Window Closed / Lapsed |