US4507277A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Composition and method for stimulating the synthesis of the melanotic pigment of the skin
Assignee: EMPRESA CUBANA IMPORTADORA Y EXPORTADORA DE PRODUCTOS MEDICOS MAXIMO GOMEZ
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Filing: 1983-04-08
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Granted: 1985-03-26
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Expires: 2003-04-08
Abstract
Abstract A composition useful in the treatment of vitiligo, a method for preparing said composition and a method of treating vitiligo with said composition wherein said composition comprises a placental alpha lipoprotein component extracted from placental cotyledons.
Inventors
- 👤 Carlos M. M. Cao
- 👤 Manuel T. Gonzalez
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 17:10
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/64; A61K8/96; A61K8/98; A61K8/981; A61K8/982; A61Q; A61Q19/00; A61Q19/04; C; C07; C07K; C07K14/00; C07K14/435; C07K14/46; C07K14/47; C07K14/4701; C07K14/4715; A61K2800/00; A61K2800/80; A61K2800/81; A61K38/00; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/85; Y10S530/851
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
61 words
A method for the treatment of vitiligo comprising: (a) isolating protein consisting essentially of alpha-lipoprotein from placental cotyledons, said alpha-lipoprotein having a spectrophotometric protein peak from 20 to 150 mcg./ml.; (b) applying the alpha-lipoprotein to the non-pigmented skin areas of a person afflicted with vitiligo; and (c) exposing the applied areas to a UV source to effect pigmentation in said areas.
Claim 2
Independent Claim
61 words
A method for the treatment of vitiligo comprising: (a) isolating protein consisting essentially of alpha-lipoprotein from placental cotyledons, said alpha-lipoprotein having a spectrophotometric protein peak from 20 to 150 mcg./ml.; (b) applying the alpha-lipoprotein to the non-pigmented skin areas of a person afflicted with vitiligo; and (c) exposing the applied areas to a UV source to effect pigmentation in said areas.
Claim 3
Dependent Claim
19 words
The method of claim 1, wherein step (b) further comprises rubbing onto the skin until the skin is reddened.
Claim 4
Dependent Claim
15 words
The method of claim 2, wherein the alpha-lipoprotein is an ethanolic solution for step (b).
Claim 5
Dependent Claim
25 words
The method of claim 3, wherein the alpha-lipoprotein is present in the solution in an amount of 30% to 50% by weight of the solution.
Claim 6
Dependent Claim
36 words
A treatment composition for providing pigmentation to non-pigmented areas of the skin of a person afflicted with vitiligo, said composition consisting essentially of a placental alpha-lipoprotein having a spectrophotometric protein peak of 20 to 150 mcg./ml.
Claim 7
Dependent Claim
36 words
A treatment composition for providing pigmentation to non-pigmented areas of the skin of a person afflicted with vitiligo, said composition consisting essentially of a placental alpha-lipoprotein having a spectrophotometric protein peak of 20 to 150 mcg./ml.
Claim 8
Dependent Claim
24 words
The composition of claim 5, wherein the alpha-lipoprotein is present in an amount of about 30% to 50% by weight in the treatment composition.
References Cited (Backward Citations)
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US4108849A
Cited
DE2540971A1
Cited
JPS53142515A
Cited
US4219467A
Cited
FR2498451A1
Cited
US4423036A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-03-25 | 1988-09-24 | 1989-03-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-03-25 | 1992-09-24 | 1993-03-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-03-25 | 1996-09-24 | 1997-03-26 | $7700.00 | Window Closed / Lapsed |