US4502490A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Patient monitoring equipment, probe for use therewith, and method of measuring anesthesia based on oesophagal contractions
Assignee: Antec Systems Ltd
•
Filing: 1981-10-23
•
Granted: 1985-03-05
•
Expires: 2001-10-23
Abstract
Abstract A method of monitoring the depth of anaesthesia of a patient, comprising stimulating contractions in the oesophagus of the patient, for example using an inflatable oesophageal balloon, obtaining signals indicative of the oesophageal contractions using a sensor, and deriving from the signals an output indicative of the rate of occurrence of signals having a magnitude greater than a preset threshold value, and apparatus for carrying out the method. An alternative aspect comprises assigning a score value to each of a plurality of different bodily functions of a patient, for example heart rate, blood pressure, degree of sweating, and formation of tears, the said score values being indicative of a depth of anaesthesia or sedation, summing the score values, and producing an output from the summed score values indicative of the amount of anaesthetic to be fed to the patient.
Inventors
- 👤 John M. Evans
- 👤 Colin C. Wise
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:38
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/03; A61B5/036; A61B5/037; A61M; A61M16/00; A61M16/04; A61M16/0402; A61M16/0415; A61M16/0434; A61M16/0436; A61M16/0438; A61M16/10; A61M16/104; A61M25/00; A61M25/10; A61M25/1018; A61M25/10181; A61M25/10184; A61M25/10185; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/05; A61N1/0517; A61N1/0519; A61N1/18; A61N1/32; A61N1/36; A61N1/36014; A61N1/36021; A61B5/42; A61M16/0003; A61M2016/0027; A61M2205/00; A61M2205/33; A61M2205/3368; A61N1/36017
Claims Analysis
Total Claims: 58
Claim 1
Independent Claim
58 words
Patient monitoring apparatus, comprising a sensor for providing signals indicative of smooth muscle contractions in the oesophagus of a patient, means for deriving from the said signals an output indicative of the depth of anaesthesia of a patient, and means adapted to connect said output deriving means to a device which operates in response to said derived output.
Claim 2
Dependent Claim
58 words
Patient monitoring apparatus, comprising a sensor for providing signals indicative of smooth muscle contractions in the oesophagus of a patient, means for deriving from the said signals an output indicative of the depth of anaesthesia of a patient, and means adapted to connect said output deriving means to a device which operates in response to said derived output.
Claim 3
Dependent Claim
28 words
Apparatus as claimed in claim 1, including discriminating means for accepting only signals of more than a desired threshold magnitude to eliminate signals arising out of non-oesophageal activities.
Claim 4
Dependent Claim
28 words
Apparatus as claimed in claim 2, wherein the said threshold magnitude is greater than the magnitude of signals produced by forced ventilation of the lungs of the patient.
Claim 5
Dependent Claim
44 words
Apparatus as claimed in claim 2, further including means for defining a preset time window during which oesophageal contractions are measured, and means for continuously measuring the number of oesophageal contractions greater than said desired threshold magnitude which occur within said preset time window.
Claim 6
Dependent Claim
17 words
Apparatus as claimed in claim 1, including means for stimulating contractions in the oesophagus of the patient.
Claim 7
Dependent Claim
33 words
Apparatus as claimed in claim 5, wherein the means for stimulating contractions in the oesophagus comprise a balloon insertable into the oesophagus or the trachea and means for applying pressure to the balloon.
Claim 8
Dependent Claim
23 words
Apparatus as claimed in claim 4, including means for supressing stimulation of the oesophagus on detection of spontaneous oesophageal contractions by the sensor.
Claim 9
Dependent Claim
32 words
Apparatus as claimed in claim 1 wherein said means deriving an output indicative of the anaethesia depth includes means for producing an output indicative of the rate of occurrence of oesophageal contractions.
Claim 10
Dependent Claim
24 words
Apparatus as claimed in claim 1, which apparatus includes means for selectively rejecting any signal at the discretion of the operator of the apparatus.
Claim 11
Dependent Claim
38 words
Apparatus as claimed in claim 1, wherein the sensor includes a balloon insertable into the oesophagus of the patient, and transducer means for producing an electrical signal in response to pressure changes in said space in the balloon.
Claim 12
Dependent Claim
19 words
Apparatus as claimed in claim 1 further including means for automatically rejecting signals of less than a predetermined duration.
Claim 13
Dependent Claim
84 words
Patient monitoring apparatus as in claim 1, which further comprises means for assigning a score value to each of a plurality of different bodily functions of a patient, the said score values being indicative of a depth of anaesthesia or sedation and one of the said score values being indicative of contractions in the oesophagus, means for summing the score values, and means for producing an output from the summed score values indicative of the amount of anaesthetic to be fed to the patient.
Claim 14
Dependent Claim
19 words
Apparatus as claimed in claim 12, including means for prompting the entry by a clinician of a score value.
Claim 15
Dependent Claim
22 words
Apparatus as claimed in claim 12, wherein the bodily functions include heart rate, blood pressure, degree of sweating, and formation of tears.
Claim 16
Dependent Claim
71 words
Apparatus for controlling the amount of an anaesthetic administered to a patient comprising sensor means for providing signals indicative of contractions in the oesophagus of a patient, means for deriving from said signals an output indicative of the depth of anaesthesia of a patient, and means for automatically controlling the amount of an anaesthetic administered to a patient in response to variation in the output indicative of the depth of anaesthesia.
Claim 17
Dependent Claim
71 words
Apparatus for controlling the amount of an anaesthetic administered to a patient comprising sensor means for providing signals indicative of contractions in the oesophagus of a patient, means for deriving from said signals an output indicative of the depth of anaesthesia of a patient, and means for automatically controlling the amount of an anaesthetic administered to a patient in response to variation in the output indicative of the depth of anaesthesia.
Claim 18
Dependent Claim
79 words
Apparatus for monitoring the depth of anaesthesia of a patient, which apparatus comprises means for stimulating contractions in the oesophagus of the patient, a sensor for providing signals indicative of the oesophageal contractions, discriminating means for accepting only signals of more than a preset threshold magnitude to eliminate signals arising from non-aesophageal activities, and means for deriving from the signals an output indicative of the rate of occurrence of signals having a magnitude greater than said preset threshold magnitude.
Claim 19
Dependent Claim
79 words
Apparatus for monitoring the depth of anaesthesia of a patient, which apparatus comprises means for stimulating contractions in the oesophagus of the patient, a sensor for providing signals indicative of the oesophageal contractions, discriminating means for accepting only signals of more than a preset threshold magnitude to eliminate signals arising from non-aesophageal activities, and means for deriving from the signals an output indicative of the rate of occurrence of signals having a magnitude greater than said preset threshold magnitude.
Claim 20
Independent Claim
47 words
A method of monitoring the depth of anaesthesia in a patient, which method comprises the steps of (a) deriving signals indicative of contraction in the oesophagus of the patient, and (b) deriving from the said signals an output indicative of the depth of anaesthesia of the patient.
Claim 21
Independent Claim
47 words
A method of monitoring the depth of anaesthesia in a patient, which method comprises the steps of (a) deriving signals indicative of contraction in the oesophagus of the patient, and (b) deriving from the said signals an output indicative of the depth of anaesthesia of the patient.
Claim 22
Dependent Claim
30 words
A method as claimed in claim 17, wherein step (b) further includes the step of deriving the output only from signals having a magnitude greater than a desired threshold value.
Claim 23
Dependent Claim
28 words
A method as claimed in claim 17, wherein step (b) further includes the step of deriving the output from the rate of occurrence of the said oesophageal contractions.
Claim 24
Dependent Claim
25 words
A method as claimed in claim 17 further comprising the step of (c) applying a stimulus to the patient to provoke contractions in the oesophagus.
Claim 25
Independent Claim
64 words
A method of controlling the depth of anaesthesia of a patient, which method comprises the steps of (a) deriving signals indicative of contractions in the oesophagus of the patient, (b) deriving from the signals an output indicative of the depth of anaesthesia of the patient, and (c) controlling the administration of anaesthetic or sedative drugs to the patient in response to the said output.
Claim 26
Independent Claim
64 words
A method of controlling the depth of anaesthesia of a patient, which method comprises the steps of (a) deriving signals indicative of contractions in the oesophagus of the patient, (b) deriving from the signals an output indicative of the depth of anaesthesia of the patient, and (c) controlling the administration of anaesthetic or sedative drugs to the patient in response to the said output.
Claim 27
Independent Claim
28 words
A method as claimed 21, wherein step (b) further includes the step of deriving the output only from signals having a magnitude greater than a desired threshold value.
Claim 28
Dependent Claim
18 words
A method as claimed in claim 21, wherein step (b) further includes the step of deriving the output.
Claim 29
Dependent Claim
25 words
A method as claimed in claim 21 further comprising the step of (d) applying a stimulus to the patient to provoke contractions in the oesophagus.
Claim 30
Dependent Claim
99 words
An elongate probe for measuring oesophogeal contractions, having a distal end adapted to pass downwardly through the oesophagus of the patient, and a proximal end adapted in use to lie externally of the mouth of the patient, the probe including stimulating means adapted in use to lie within the oesophagus of a patient and operable by means external to the patient for stimulating the oesophagus, to cause contractions therein, pressure sensing means adapted in use to lie within the oesophagus of the patient for enabling the measurement of pressure within the oesophagus, thereby to sense contractions of the oesophagus.
Claim 31
Dependent Claim
99 words
An elongate probe for measuring oesophogeal contractions, having a distal end adapted to pass downwardly through the oesophagus of the patient, and a proximal end adapted in use to lie externally of the mouth of the patient, the probe including stimulating means adapted in use to lie within the oesophagus of a patient and operable by means external to the patient for stimulating the oesophagus, to cause contractions therein, pressure sensing means adapted in use to lie within the oesophagus of the patient for enabling the measurement of pressure within the oesophagus, thereby to sense contractions of the oesophagus.
Claim 32
Dependent Claim
35 words
A probe as claimed in claim 25 wherein the stimulating means comprises a sealed inflatable balloon, and the probe comprises a lumen in fluid communication between the balloon and the proximal end of the probe.
Claim 33
Dependent Claim
19 words
A probe as claimed in claim 26 wherein the maximum diameter of the inflatable balloon is about 2 cm.
Claim 34
Dependent Claim
19 words
A probe as claimed in claim 27 wherein the stimulating means comprises two inflatable balloons spaced along the probe.
Claim 35
Dependent Claim
21 words
A probe as claimed in claim 28 including means to cause the two inflatable stimulating balloons to expand at differing rates.
Claim 36
Dependent Claim
29 words
A probe as claimed in claim 25 wherein the stimulating means includes a pair of electrodes on the probe, and means for supplying an electrical voltage to the electrodes.
Claim 37
Dependent Claim
21 words
A probe as claimed in claim 30 wherein the pressure sensing balloon includes a foam insert to maintain the balloon volume.
Claim 38
Dependent Claim
17 words
A probe as claimed in claim 25 wherein the pressure sensing means includes an inflatable sensing balloon.
Claim 39
Dependent Claim
33 words
A probe as claimed claim 32 including a lumen in fluid communication between the said sensing ballon and means on the proximal end of the tube for the connection of a pressure transducer.
Claim 40
Dependent Claim
19 words
A probe as claimed in claim 32 wherein the maximum diameter of the sensing balloon is about 2 cm.
Claim 41
Dependent Claim
20 words
A probe as claimed in claim 32 wherein the sensing balloon has a length of from 3 to 5 cm.
Claim 42
Dependent Claim
25 words
A probe as claimed in claim 32 wherein a small leak is provided to permit the equalisation of permanent pressure changes in the sensing balloon.
Claim 43
Dependent Claim
20 words
A probe as claimed in claim 32 which also incorporate a sealed inflatable stimulating balloon as defined in claim 26.
Claim 44
Dependent Claim
17 words
A probe as claimed in claim 37 wherein the stimulating balloon and the sensing balloon are concentric.
Claim 45
Dependent Claim
22 words
A probe as claimed in claim 25 including a pressure transducer adapted in use to lie in the oesophagus of the patient.
Claim 46
Dependent Claim
20 words
A probe as claimed in claim 25 including means for sensing the pressure at two points spaced along the oesophagus.
Claim 47
Dependent Claim
22 words
A probe as claimed in claim 4 wherein the said points are spaced from each other by from 10 to 15 cm.
Claim 48
Dependent Claim
14 words
A probe as claimed in claim 25 including a microphone or a temperature sensor.
Claim 49
Dependent Claim
84 words
A probe for measuring oesophogeal contractions, comprising an elongate body portion for insertion into the oesophagus and having at least first and second lumens sealed with respect to each other, the first lumen being in communication at its distal end with a sensing balloon for sensing oesophageal pressure, and being provided at its proximal end with means for connection to a pressure measuring device, and the second lumen being adapted to receive a fluid under pressure to stimulate the oesophagus to cause contractions therein.
Claim 50
Dependent Claim
84 words
A probe for measuring oesophogeal contractions, comprising an elongate body portion for insertion into the oesophagus and having at least first and second lumens sealed with respect to each other, the first lumen being in communication at its distal end with a sensing balloon for sensing oesophageal pressure, and being provided at its proximal end with means for connection to a pressure measuring device, and the second lumen being adapted to receive a fluid under pressure to stimulate the oesophagus to cause contractions therein.
Claim 51
Dependent Claim
65 words
Patient monitoring apparatus, which comprises means for assigning a score value to each of a plurality of different bodily functions of a patient, the said score values being indicative of a depth of anaesthesia or sedation, means for summing the score values, and means for producing an output from the summed score values indicative of the amount of anaesthetic to be fed to the patient.
Claim 52
Dependent Claim
65 words
Patient monitoring apparatus, which comprises means for assigning a score value to each of a plurality of different bodily functions of a patient, the said score values being indicative of a depth of anaesthesia or sedation, means for summing the score values, and means for producing an output from the summed score values indicative of the amount of anaesthetic to be fed to the patient.
Claim 53
Dependent Claim
18 words
Apparatus as claimed in claim 14, including means for measuring at least one of the said bodily functions.
Claim 54
Dependent Claim
19 words
Apparatus as claimed in claim 44, including means for prompting the entry by a clinician of a score value.
Claim 55
Dependent Claim
25 words
Apparatus as claimed in claim 44, including means for automatically controlling the amount of anaesthetic delivered to the patient in response to the said output.
Claim 56
Dependent Claim
22 words
Apparatus as claimed in claim 47, wherein the bodily functions include heart rate, blood pressure, degree of sweating, and formation of tears.
Claim 57
Independent Claim
57 words
A method of monitoring the depth of anaesthesia of a patient, which method comprises assigning a score value to each of a plurality of different bodily functions, the said score values being indicative of a depth of anaesthesia, and summing the score values to obtain a total score indicative of the depth of anaesthesia of the patient.
Claim 58
Independent Claim
57 words
A method of monitoring the depth of anaesthesia of a patient, which method comprises assigning a score value to each of a plurality of different bodily functions, the said score values being indicative of a depth of anaesthesia, and summing the score values to obtain a total score indicative of the depth of anaesthesia of the patient.
References Cited (Backward Citations)
FR790091A
Cited
US3171892A
Cited
US3898983A
Cited
US4231255A
Cited
US4214593A
Cited
US4235242A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-03-04 | 1988-09-03 | 1989-03-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-03-04 | 1992-09-03 | 1993-03-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-03-04 | 1996-09-03 | 1997-03-05 | $7700.00 | Window Closed / Lapsed |