Patent US3181117A successfully refreshed from Google Patents.
US4500676A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Hyaluronate modified polymeric articles
Assignee: Sanofi Biosurgery Inc
•
Filing: 1983-12-15
•
Granted: 1985-02-19
•
Expires: 2003-12-15
Abstract
Abstract Polymeric materials (and articles made therefrom) including polyurethanes, polyesters, polyolefins, polyamides, polysiloxanes, vinylic and acrylic polymers are rendered biocompatible by including with the polymeric material hyaluronic acid or a salt thereof. The hyaluronic acid may be coated onto the surface of the polymeric material, dispersed throughout the body of the polymeric material, or both. The hyaluronic acid on the surface of the polymeric material may optionally be cross-linked. The biocompatible polymeric materials are used in the making of various prosthetic devices including heart valves, intraocular lenses, vascular grafts, pacemaker leads and the like.
Inventors
- 👤 Endre A. Balazs
- 👤 Adolf Leshchiner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:42
CPC Classifications
C; C08; C08G; C08G85/00; C08G85/004; A; A61; A61L; A61L27/00; A61L27/14; A61L27/26; A61L33/00; A61L33/06; A61L33/062; C08F; C08F8/00; C08K; C08K5/00; C08K5/0008; C08K5/0025; C08L; C08L5/00; C08L83/00; C08L83/04; C08L83/08; A61F; A61F2/00; A61F2/02; A61F2/14; A61F2/16; Y; Y10; Y10T; Y10T428/00; Y10T428/31504; Y10T428/31551; Y10T428/31591; Y10T428/31652; Y10T428/31663; Y10T428/31725; Y10T428/31768; Y10T428/31772; Y10T428/31786; Y10T428/3179; Y10T428/31855; Y10T428/3188
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
20 words
A composition of matter comprising a polymeric material modified by the inclusion therein of hyaluronic acid or a salt thereof.
Claim 2
Dependent Claim
20 words
A composition of matter comprising a polymeric material modified by the inclusion therein of hyaluronic acid or a salt thereof.
Claim 3
Dependent Claim
31 words
A composition according to claim 1 wherein the polymeric material is a polyurethane, polyolefin, a vinylic polymer or copolymer, an acrylic polymer or copolymer, a polyamide, a polyester or a polysiloxane.
Claim 4
Dependent Claim
13 words
A composition according to claim 2 wherein the polymeric material is a polyurethane.
Claim 5
Dependent Claim
18 words
A composition according to claim 3 wherein the polyurethane is an aliphatic, aromatic or araliphatic polyetherurethane or polyesterurethane.
Claim 6
Dependent Claim
23 words
A composition according to claim 3 wherein the included hyaluronic acid or salt thereof is coated onto the surface of the polymeric material.
Claim 7
Dependent Claim
21 words
A composition according to claim 3 wherein the included hyaluronic acid is covalently bonded to the surface of the polymeric material.
Claim 8
Dependent Claim
23 words
A composition according to claim 3 wherein the hyaluronic acid is distributed throughout the body and on the surface of the polymeric material.
Claim 9
Dependent Claim
19 words
A composition according to claim 5 wherein the hyaluronic acid on the surface of the polymeric material is cross-linked.
Claim 10
Dependent Claim
19 words
A composition according to claim 6 wherein the hyaluronic acid on the surface of the polymeric material is cross-linked.
Claim 11
Dependent Claim
19 words
A composition according to claim 7 wherein the hyaluronic acid on the surface of the polymeric material is cross-linked.
Claim 12
Dependent Claim
11 words
A formed article made from the composition according to claim 3.
Claim 13
Dependent Claim
17 words
An article according to claim 11 which is a casting, a film, a fiber or a fabric.
Claim 14
Dependent Claim
13 words
A composition according to claim 2 wherein the polymeric material is a polyester.
Claim 15
Dependent Claim
23 words
A composition according to claim 13 wherein the included hyaluronic acid or salt thereof is coated onto the surface of the polymeric material.
Claim 16
Dependent Claim
19 words
A composition according to claim 14 wherein the hyaluronic acid on the surface of the polymeric material is cross-linked.
Claim 17
Dependent Claim
11 words
A formed article made from the composition according to claim 13.
Claim 18
Dependent Claim
17 words
An article according to claim 16 which is a casting, a film, a fiber or a fabric.
Claim 19
Dependent Claim
14 words
A composition according to claim 2 wherein the polymeric material is a vinylic polymer.
Claim 20
Dependent Claim
14 words
A composition according to claim 18 wherein the vinylic polymer is a polyvinyl chloride.
Claim 21
Dependent Claim
23 words
A composition according to claim 19 wherein the included hyaluronic acid or salt thereof is coated onto the surface of the polymeric material.
Claim 22
Dependent Claim
19 words
A composition according to claim 20 wherein the hyaluronic acid on the surface of the polymeric material is cross-linked.
Claim 23
Dependent Claim
11 words
A formed article made from the composition according to claim 18.
Claim 24
Dependent Claim
17 words
An article according to claim 22 which is a casting, a film, a fiber or a fabric.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-02-19 | 1988-08-20 | 1989-02-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-02-19 | 1992-08-20 | 1993-02-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-02-19 | 1996-08-20 | 1997-02-19 | $7700.00 | Window Closed / Lapsed |