US4490407A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for preparing galenic formulations particularly for pharmaceutical, dietetical, cosmetic and diagnostic uses
Assignee: Cephalon France SAS
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Filing: 1983-04-07
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Granted: 1984-12-25
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Expires: 2003-04-07
Abstract
Abstract A method for preparing a galenic formulation for pharmaceutical, dietetic, cosmetic or diagnostic use, comprising forming a liquid mixture containing at least one active ingredient and at least one film-forming substance, spraying the mixture at a temperature between 50° and 150° C. to form droplets, drying the droplets in a current of drying gas at a temperature between 100° and 150° C. to obtain coated granules with a diameter comprised between 10 and 20μ, collecting the coated granules, and subjecting the collected granules to lyophilization.
Inventors
- 👤 Louis Lafon
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 04:34
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/02; A61K8/11; A61K8/18; A61K8/30; A61K8/31; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1617; A61K9/1623; A61K9/1629; A61K9/1635; A61K9/1641; A61K9/1682; A61K9/1694; A61Q; A61Q19/00; A61K2800/00; A61K2800/40; A61K2800/41; A61K2800/412
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
85 words
A method for preparing a galenic formulation for pharmaceutical, dietetic, cosmetic or diagnostic use, comprising forming a liquid mixture containing at least one active ingredient and at least one film-forming substance, spraying said mixture at a temperature between 50° and 150° C. to form droplets, drying said droplets in a current of drying gas at a temperature between 100° and 150° C. to obtain coated granules with a diameter comprised between 10 and 120μ, collecting said coated granules, and subjecting said collected granules to lyophilization.
Claim 2
Independent Claim
85 words
A method for preparing a galenic formulation for pharmaceutical, dietetic, cosmetic or diagnostic use, comprising forming a liquid mixture containing at least one active ingredient and at least one film-forming substance, spraying said mixture at a temperature between 50° and 150° C. to form droplets, drying said droplets in a current of drying gas at a temperature between 100° and 150° C. to obtain coated granules with a diameter comprised between 10 and 120μ, collecting said coated granules, and subjecting said collected granules to lyophilization.
Claim 3
Dependent Claim
35 words
A method according to claim 1, wherein the film-forming substance is selected from the group consisting of: ethylcellulose, cellulose acetophthalate, polyvinylacetate-diethylaminoacetate, copolymers of 2-methyl-5-vinylpyridine, methacrylic acid, methacrylates and the polymers or copolymers of dimethylaminoethyl methacrylate.
Claim 4
Dependent Claim
41 words
A method according to claim 1, wherein the film-forming substance is selected from the group consisting of (i) glycerides and polyglycerides of fatty acids, (ii) polyethyleneglycol, (iii) polyoxyethylene copolymers and polyoxypropylene copolymers, (iv) urea and urethane, and (v) a mixture thereof.
Claim 5
Dependent Claim
23 words
A method according to claim 3 wherein the glycerides are selected from the group consisting of glycerol monostearate, glycerol distearate and glycerol palmitostearate.
Claim 6
Dependent Claim
35 words
A method according to claim 1, wherein the mixture of film-forming substances with at least one active ingredient comprises at least an alcohol selected from the group consisting of limonene, cineol, menthol, eugenol and vanillin.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-25 | 1988-06-25 | 1988-12-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-25 | 1992-06-25 | 1992-12-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-25 | 1996-06-25 | 1996-12-25 | $7700.00 | Window Closed / Lapsed |