US4490379A
Expired / Lapsed
US
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Method of reducing intraocular pressure and treating glaucoma using corynanthine
Assignee: MT SINAI SCHOOL OF MEDICINE OF CITY UNIVERSITY OF NEW YORK ONE GUSTAVE L LEVY PLACE NEW YORK NY 10029 A CORP OF NEW YORK
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Filing: 1984-04-04
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Granted: 1984-12-25
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Expires: 2004-04-04
Abstract
Abstract This invention relates to a method of reducing intraocular pressure and treating glaucoma in mammals which comprises administering topically to the eye a pharmaceutically acceptable salt isomeric to yohimbine and stereochemically similar to corynanthine in an amount effective to reduce intraocular pressure.
Inventors
- 👤 Steven Podos
- 👤 Janet B. Serle
- 👤 Thomas Mittag
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 23:19
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61K31/475
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
30 words
A method of reducing intraocular pressure in mammals which comprises applying topically to the eye corynanthine or a pharmaceutically acceptable salt thereof in an amount effective to reduce intraocular pressure.
Claim 2
Independent Claim
30 words
A method of reducing intraocular pressure in mammals which comprises applying topically to the eye corynanthine or a pharmaceutically acceptable salt thereof in an amount effective to reduce intraocular pressure.
Claim 3
Dependent Claim
17 words
A method of reducing intraocular pressure as described in claim 1 wherein the salt is corynanthine tartrate.
Claim 4
Independent Claim
29 words
A method of treating glaucoma in mammals which comprises applying topically to the eye corynanthine or a pharmaceutically acceptable salt thereof in an amount effective to reduce intraocular pressure.
Claim 5
Independent Claim
29 words
A method of treating glaucoma in mammals which comprises applying topically to the eye corynanthine or a pharmaceutically acceptable salt thereof in an amount effective to reduce intraocular pressure.
Claim 6
Dependent Claim
16 words
A method of treating glaucoma as described in claim 3 wherein the salt is corynanthine tartrate.
Claim 7
Dependent Claim
28 words
A method of treating glaucoma as described in claim 4 wherein the corynanthine tartrate is applied topically as an aqueous solution containing about 2-5% by weight corynanthine tartrate.
Claim 8
Dependent Claim
29 words
A method of reducing intraocular pressure as described in claim 2 wherein the corynanthine tartrate is applied topically as an aqueous solution containing about 2-5% by weight corynanthine tartrate.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-25 | 1988-06-25 | 1988-12-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-25 | 1992-06-25 | 1992-12-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-25 | 1996-06-25 | 1996-12-25 | $7700.00 | Window Closed / Lapsed |