US4489080A
Expired / Lapsed
US
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Process for analgesic treatment
Assignee: Pharmacia and Upjohn Co
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Filing: 1982-12-06
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Granted: 1984-12-18
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Expires: 2002-12-06
Abstract
Abstract An improved process for the management of pain by concommittant administration of narcotic analgesics and flurbiprofen or salt or ester thereof. Process for reducing dosage and dosage forms are disclosed.
Inventors
- 👤 Pavel L. Lomen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 04:33
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61K31/485
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
50 words
In the process of treating pain by the systemic administration of analgetic amounts of narcotic analgesics the improvement comprising the step of concomitant systemic administration of an analgetic amount of 3-fluro-4-phenylhydratropic acid or an alkyl ester of from one to eight carbon atoms, inclusive, or a pharmacologically acceptable salt, thereof.
Claim 2
Dependent Claim
50 words
In the process of treating pain by the systemic administration of analgetic amounts of narcotic analgesics the improvement comprising the step of concomitant systemic administration of an analgetic amount of 3-fluro-4-phenylhydratropic acid or an alkyl ester of from one to eight carbon atoms, inclusive, or a pharmacologically acceptable salt, thereof.
Claim 3
Dependent Claim
48 words
A process for treating moderate to severe pain in humans comprising the concomitant systemic administration of an analgetic amount of a narcotic analgesic and an analgetic amount of 3-fluoro-4-phenylhydratropic acid or an alkyl ester of from one to eight carbon atoms, inclusive, or a pharmacologically acceptable salt, thereof.
Claim 4
Dependent Claim
48 words
A process for treating moderate to severe pain in humans comprising the concomitant systemic administration of an analgetic amount of a narcotic analgesic and an analgetic amount of 3-fluoro-4-phenylhydratropic acid or an alkyl ester of from one to eight carbon atoms, inclusive, or a pharmacologically acceptable salt, thereof.
Claim 5
Dependent Claim
37 words
An analgesic composition, in unit dosage form, comprising a synergistic analgetic amount of a narcotic analgesic and 3-fluoro-4-phenylhydratropic acid or an alkyl ester of from one to eight carbon atoms, inclusive, or a pharmacologically acceptable salt, thereof.
Claim 6
Dependent Claim
37 words
An analgesic composition, in unit dosage form, comprising a synergistic analgetic amount of a narcotic analgesic and 3-fluoro-4-phenylhydratropic acid or an alkyl ester of from one to eight carbon atoms, inclusive, or a pharmacologically acceptable salt, thereof.
Claim 7
Dependent Claim
27 words
The process of claim 1 wherein the narcotic analgesic is selected from the group consisting of morphine, hydromorphone, oxymorphone, levorphanol, methadone, meperidine, anileridine, alphaprodine, fentanol, or codeine.
Claim 8
Dependent Claim
21 words
The process of claim 1 wherein the narcotic analgesic is selected from the group consisting of morphine, hydromorphone, oxymorphone or codeine.
Claim 9
Dependent Claim
27 words
The process of claim 2 wherein the narcotic analgesic is selected from the group consisting of morphine, hydromorphone, oxymorphone, levorphanol, methadone, meperidine, anileridine, alphaprodine, fentanol, or codeine.
Claim 10
Dependent Claim
21 words
The process of claim 2 wherein the narcotic analgesic is selected from the group consisting of morphine, hydromorphone, oxymorphone or codeine.
Claim 11
Dependent Claim
27 words
The composition of claim 3 wherein the narcotic analgesic is selected from the group consisting of morphine, hydromorphine, oxymorphone, levorphanol, methadone, meperidine, anileridine, alphaprodine, fentanol, or codeine.
Claim 12
Dependent Claim
21 words
The composition of claim 3 wherein the narcotic analgesic is selected from the group consisting of morphine, hydromorphone, oxymorphone or codeine.
Claim 13
Dependent Claim
11 words
The composition of claim 3 wherein the narcotic analgesic is codeine.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-18 | 1988-06-18 | 1988-12-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-18 | 1992-06-18 | 1992-12-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-18 | 1996-06-18 | 1996-12-18 | $7700.00 | Window Closed / Lapsed |